7RSS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rss by Molmil](/molmil-images/mine/7rss) | Kod-RI incorporating DNA, n+2 | 分子名称: | DNA polymerase, Primer, Template | 著者 | Hajjar, M, Chim, N, Chaput, J.C. | 登録日 | 2021-08-11 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic Acids Res., 50, 2022
|
|
7RSR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rsr by Molmil](/molmil-images/mine/7rsr) | Kod-RI incorporating PMT, n+2 | 分子名称: | DNA polymerase, Primer, Template | 著者 | Hajjar, M, Chim, N, Chaput, J.C. | 登録日 | 2021-08-11 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic Acids Res., 50, 2022
|
|
8TJ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8tj5 by Molmil](/molmil-images/mine/8tj5) | Inner spoke ring of the yeast NPC | 分子名称: | Nucleoporin 59, Nucleoporin NIC96, Nucleoporin NSP1, ... | 著者 | Akey, C.W, Echeverria, I, Ouch, C, Fernandez-Martinez, J, Rout, M.P. | 登録日 | 2023-07-20 | 公開日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | 主引用文献 | Implications of a multiscale structure of the yeast nuclear pore complex. Mol.Cell, 83, 2023
|
|
1MNM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mnm by Molmil](/molmil-images/mine/1mnm) | |
3R1H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3r1h by Molmil](/molmil-images/mine/3r1h) | Crystal structure of the Class I ligase ribozyme-substrate preligation complex, C47U mutant, Ca2+ bound | 分子名称: | 5'-R(*UP*CP*CP*AP*GP*UP*A)-3', CALCIUM ION, Class I ligase ribozyme, ... | 著者 | Shechner, D.M, Bartel, D.P. | 登録日 | 2011-03-10 | 公開日 | 2011-08-31 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | The structural basis of RNA-catalyzed RNA polymerization. Nat.Struct.Mol.Biol., 18, 2011
|
|
3R1L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3r1l by Molmil](/molmil-images/mine/3r1l) | Crystal structure of the Class I ligase ribozyme-substrate preligation complex, C47U mutant, Mg2+ bound | 分子名称: | 5'-R(*UP*CP*CP*AP*GP*UP*A)-3', Class I ligase ribozyme, MAGNESIUM ION, ... | 著者 | Shechner, D.M, Bartel, D.P. | 登録日 | 2011-03-10 | 公開日 | 2011-08-31 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.125 Å) | 主引用文献 | The structural basis of RNA-catalyzed RNA polymerization. Nat.Struct.Mol.Biol., 18, 2011
|
|
1U7B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1u7b by Molmil](/molmil-images/mine/1u7b) | |
1YN6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yn6 by Molmil](/molmil-images/mine/1yn6) | Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a peptide from the influenza A acid polymerase | 分子名称: | 10-mer peptide from RNA-directed RNA polymerase subunit P2, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Turner, S.J, Kedzierska, K, Komodromou, H, La Gruta, N.L, Dunstone, M.A, Webb, A.I, Webby, R, Walden, H, Xie, W, McCluskey, J, Purcell, A.W, Rossjohn, J, Doherty, P.C. | 登録日 | 2005-01-23 | 公開日 | 2005-06-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations Nat.Immunol., 6, 2005
|
|
4N0O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4n0o by Molmil](/molmil-images/mine/4n0o) | |
6OTC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6otc by Molmil](/molmil-images/mine/6otc) | Synthetic Fab bound to Marburg virus VP35 interferon inhibitory domain | 分子名称: | CHLORIDE ION, GLYCEROL, Polymerase cofactor VP35, ... | 著者 | Amatya, P, Chen, G, Borek, D, Sidhu, S.S, Leung, D.W. | 登録日 | 2019-05-02 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Inhibition of Marburg Virus RNA Synthesis by a Synthetic Anti-VP35 Antibody. Acs Infect Dis., 5, 2019
|
|
4N0N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4n0n by Molmil](/molmil-images/mine/4n0n) | Crystal structure of Arterivirus nonstructural protein 10 (helicase) | 分子名称: | MAGNESIUM ION, Replicase polyprotein 1ab, SULFATE ION, ... | 著者 | Deng, Z, Chen, Z. | 登録日 | 2013-10-02 | 公開日 | 2014-01-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for the regulatory function of a complex zinc-binding domain in a replicative arterivirus helicase resembling a nonsense-mediated mRNA decay helicase. Nucleic Acids Res., 42, 2014
|
|
3GPQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gpq by Molmil](/molmil-images/mine/3gpq) | Crystal structure of macro domain of Chikungunya virus in complex with RNA | 分子名称: | Non-structural protein 3, RNA (5'-R(*AP*AP*A)-3') | 著者 | Malet, H, Jamal, S, Coutard, B, Canard, B. | 登録日 | 2009-03-23 | 公開日 | 2009-07-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket J.Virol., 83, 2009
|
|
2AJQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ajq by Molmil](/molmil-images/mine/2ajq) | |
4KL6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kl6 by Molmil](/molmil-images/mine/4kl6) | Crystal structure of dimeric form of NpuDnaE intein | 分子名称: | DNA-directed DNA polymerase,Nucleic acid binding, OB-fold, tRNA/helicase-type | 著者 | Aranko, A.S, Oeemig, J.S, Kajander, T, Iwai, H. | 登録日 | 2013-05-07 | 公開日 | 2013-09-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Intermolecular domain swapping induces intein-mediated protein alternative splicing. Nat.Chem.Biol., 9, 2013
|
|
4KL5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kl5 by Molmil](/molmil-images/mine/4kl5) | Crystal structure of NpuDnaE intein | 分子名称: | CITRIC ACID, DNA polymerase III, alpha subunit, ... | 著者 | Aranko, A.S, Oeemig, J.S, Kajander, T, Iwai, H. | 登録日 | 2013-05-07 | 公開日 | 2013-09-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Intermolecular domain swapping induces intein-mediated protein alternative splicing. Nat.Chem.Biol., 9, 2013
|
|
4FRN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4frn by Molmil](/molmil-images/mine/4frn) | Crystal structure of the cobalamin riboswitch regulatory element | 分子名称: | BARIUM ION, Cobalamin riboswitch aptamer domain, Hydroxocobalamin | 著者 | Reyes, F.E, Johnson, J.E, Polaski, J.T, Batey, R.T. | 登録日 | 2012-06-26 | 公開日 | 2012-10-17 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.43 Å) | 主引用文献 | B12 cofactors directly stabilize an mRNA regulatory switch. Nature, 492, 2012
|
|
8C13
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c13 by Molmil](/molmil-images/mine/8c13) | Crystal structure of pVHL:ElonginC:ElonginB complex bound to PROTAC JW48 | 分子名称: | (2~{S},4~{R})-1-[(2~{S})-2-[3-[2-[2-[2-(acetamidomethyl)-4-(6,7-dihydro-5~{H}-pyrrolo[1,2-a]imidazol-2-yl)phenoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | 著者 | Kraemer, A, Weckesser, J, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2022-12-20 | 公開日 | 2022-12-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization. Cell Chem Biol, 30, 2023
|
|
4GMA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4gma by Molmil](/molmil-images/mine/4gma) | Crystal structure of the adenosylcobalamin riboswitch | 分子名称: | Adenosylcobalamin, Adenosylcobalamin riboswitch | 著者 | Reyes, F.E, Johnson, J.E, Polaski, J.T, Batey, R.T. | 登録日 | 2012-08-15 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.94 Å) | 主引用文献 | B12 cofactors directly stabilize an mRNA regulatory switch. Nature, 492, 2012
|
|
6JYJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jyj by Molmil](/molmil-images/mine/6jyj) | Crystal structure of FAM46B (TENT5B) | 分子名称: | CITRATE ANION, Terminal nucleotidyltransferase 5B | 著者 | Zhang, H, Hu, J.L, Gao, S. | 登録日 | 2019-04-26 | 公開日 | 2020-03-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.693199 Å) | 主引用文献 | FAM46B is a prokaryotic-like cytoplasmic poly(A) polymerase essential in human embryonic stem cells. Nucleic Acids Res., 48, 2020
|
|
5H0S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h0s by Molmil](/molmil-images/mine/5h0s) | EM Structure of VP1A and VP1B | 分子名称: | VP1 | 著者 | Li, X, Zhou, N, Xu, B, Chen, W, Zhu, B, Wang, X, Wang, J, Liu, H, Cheng, L. | 登録日 | 2016-10-06 | 公開日 | 2017-01-25 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Near-Atomic Resolution Structure Determination of a Cypovirus Capsid and Polymerase Complex Using Cryo-EM at 200kV J. Mol. Biol., 429, 2017
|
|
4FRG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4frg by Molmil](/molmil-images/mine/4frg) | Crystal structure of the cobalamin riboswitch aptamer domain | 分子名称: | Hydroxocobalamin, IRIDIUM (III) ION, MAGNESIUM ION, ... | 著者 | Reyes, F.E, Johnson, J.E, Polaski, J.T, Batey, R.T. | 登録日 | 2012-06-26 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | B12 cofactors directly stabilize an mRNA regulatory switch. Nature, 492, 2012
|
|
1U3K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1u3k by Molmil](/molmil-images/mine/1u3k) | |
6ZHC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zhc by Molmil](/molmil-images/mine/6zhc) | PROTAC6 mediated complex of VHL:EloB:EloC and Bcl-xL | 分子名称: | 1,2-ETHANEDIOL, 2-[8-(1,3-benzothiazol-2-ylcarbamoyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]-5-[3-[4-[3-[2-[2-[2-[2-[2-[3-[[(2~{S})-3,3-dimethyl-1-[(2~{S},4~{R})-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]-4-oxidanyl-pyrrolidin-1-yl]-1-oxidanylidene-butan-2-yl]amino]-3-oxidanylidene-propoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]prop-1-ynyl]phenoxy]propyl]-1,3-thiazole-4-carboxylic acid, Bcl-2-like protein 1, ... | 著者 | Chung, C. | 登録日 | 2020-06-22 | 公開日 | 2020-08-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structural Insights into PROTAC-Mediated Degradation of Bcl-xL. Acs Chem.Biol., 15, 2020
|
|
8BB5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bb5 by Molmil](/molmil-images/mine/8bb5) | Structure of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC with Aryl linker | 分子名称: | 1,2-ETHANEDIOL, Elongin-B, Elongin-C, ... | 著者 | Kraemer, A, Doelle, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2022-10-12 | 公開日 | 2022-11-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization. Cell Chem Biol, 30, 2023
|
|
8BB4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bb4 by Molmil](/molmil-images/mine/8bb4) | Structure of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC with C3 linker | 分子名称: | Elongin-B, Elongin-C, WD repeat-containing protein 5, ... | 著者 | Kraemer, A, Doelle, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2022-10-12 | 公開日 | 2022-11-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization. Cell Chem Biol, 30, 2023
|
|