6OTC

Synthetic Fab bound to Marburg virus VP35 interferon inhibitory domain

Summary for 6OTC

Entry DOI	10.2210/pdb6otc/pdb
Descriptor	Polymerase cofactor VP35, sFab H3 heavy chain, sFab H3 light chain, ... (6 entities in total)
Functional Keywords	marburg virus, fab, viral protein-immune system complex, viral protein/immune system
Biological source	Lake Victoria marburgvirus (strain Popp-67) (MARV) More
Total number of polymer chains	3
Total formula weight	65360.52
Authors	Amatya, P.,Chen, G.,Borek, D.,Sidhu, S.S.,Leung, D.W. (deposition date: 2019-05-02, release date: 2019-06-05, Last modification date: 2023-10-11)
Primary citation	Amatya, P.,Wagner, N.,Chen, G.,Luthra, P.,Shi, L.,Borek, D.,Pavlenco, A.,Rohrs, H.,Basler, C.F.,Sidhu, S.S.,Gross, M.L.,Leung, D.W. Inhibition of Marburg Virus RNA Synthesis by a Synthetic Anti-VP35 Antibody. Acs Infect Dis., 5:1385-1396, 2019 Cited by PubMed: 31120240 DOI: 10.1021/acsinfecdis.9b00091 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation