6OTC
Synthetic Fab bound to Marburg virus VP35 interferon inhibitory domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Polymerase cofactor VP35 | polymer | 129 | 14132.4 | 1 | UniProt (Q03039) Pfam (PF02097) In PDB | Lake Victoria marburgvirus (strain Popp-67) (MARV) | Marburg VP35, mVP35 |
| 2 | H | sFab H3 heavy chain | polymer | 240 | 25834.7 | 1 | synthetic construct | ||
| 3 | L | sFab H3 light chain | polymer | 232 | 25265.9 | 1 | synthetic construct | ||
| 4 | H | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | H | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | water | water | 18.0 | 623 | Chemie (HOH) |
Sequence modifications
A: 204 - 329 (UniProt: Q03039)
| PDB | External Database | Details |
|---|---|---|
| Gly 201 | - | expression tag |
| His 202 | - | expression tag |
| Met 203 | - | expression tag |
| Met 277 | Leu 277 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 65233.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 127.5 | |
| All* | Total formula weight | 65360.5 |
