6U0T
| Protofilament Ribbon Flagellar Proteins Rib43a-S | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Ichikawa, M, Khalifa, A.A.Z, Vargas, J, Basu, K, Bui, K.H. | 登録日 | 2019-08-14 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | 主引用文献 | Tubulin lattice in cilia is in a stressed form regulated by microtubule inner proteins. Proc.Natl.Acad.Sci.USA, 116, 2019
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6U0H
| Tubulin lattice of the ciliary doublet microtubule from Tetrahymena thermophila | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Ichikawa, M, Khalifa, A.A.Z, Vargas, J, Basu, K, Bui, K.H. | 登録日 | 2019-08-14 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Tubulin lattice in cilia is in a stressed form regulated by microtubule inner proteins. Proc.Natl.Acad.Sci.USA, 116, 2019
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6U0U
| Protofilament Ribbon Flagellar Proteins Rib43a-L | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Ichikawa, M, Khalifa, A.A.Z, Vargas, J, Basu, K, Bui, K.H. | 登録日 | 2019-08-14 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | 主引用文献 | Tubulin lattice in cilia is in a stressed form regulated by microtubule inner proteins. Proc.Natl.Acad.Sci.USA, 116, 2019
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6SI9
| FtsZ-refold | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Cell division protein FtsZ, ... | 著者 | Fernandez-Tornero, C, Andreu, J.M, Ruiz, F.M. | 登録日 | 2019-08-09 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus. Febs J., 287, 2020
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6KNZ
| Crystal structure of T2R-TTL-KXO1 complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[5-[4-(2-morpholin-4-ylethoxy)phenyl]pyridin-2-yl]-~{N}-(phenylmethyl)ethanamide, CALCIUM ION, ... | 著者 | Chen, Q, Yu, Y. | 登録日 | 2019-08-07 | 公開日 | 2019-10-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.475 Å) | 主引用文献 | Reversible binding of the anticancer drug KXO1 (tirbanibulin) to the colchicine-binding site of beta-tubulin explains KXO1's low clinical toxicity. J.Biol.Chem., 294, 2019
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6SES
| Tubulin-B2 complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Guo, B, Rodriguez-Gabin, A, Prota, A.E, Muehlethaler, T, Zhang, N, Ye, K, Steinmetz, M.O, Band Horwitz, S, Smith III, A.B, McDaid, H.M. | 登録日 | 2019-07-30 | 公開日 | 2020-07-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence. Mol.Pharmacol., 98, 2020
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6KIQ
| Complex of yeast cytoplasmic dynein MTBD-High and MT with DTT | 分子名称: | Alpha tubulin, Dynein heavy chain, cytoplasmic, ... | 著者 | Komori, Y, Nishida, N, Shimada, I, Kikkawa, M. | 登録日 | 2019-07-19 | 公開日 | 2020-03-04 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | 主引用文献 | Structural basis for two-way communication between dynein and microtubules. Nat Commun, 11, 2020
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6KIO
| Complex of yeast cytoplasmic dynein MTBD-High and MT without DTT | 分子名称: | Dynein heavy chain, cytoplasmic, Tubulin alpha-1A chain, ... | 著者 | Komori, Y, Nishida, N, Shimada, I, Kikkawa, M. | 登録日 | 2019-07-19 | 公開日 | 2020-03-04 | 最終更新日 | 2020-03-11 | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | 主引用文献 | Structural basis for two-way communication between dynein and microtubules. Nat Commun, 11, 2020
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6S9E
| Tubulin-GDP.AlF complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ALUMINUM FLUORIDE, CALCIUM ION, ... | 著者 | Oliva, M.A, Estevez-Gallego, J, Diaz, J.F, Prota, A.E, Steinmetz, M.O, Balaguer, F.A, Lucena-Agell, D. | 登録日 | 2019-07-12 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural model for differential cap maturation at growing microtubule ends. Elife, 9, 2020
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6S8M
| S. pombe microtubule decorated with Cut7 motor domain in the AMPPNP state | 分子名称: | 7,11-DIHYDROXY-8,8,10,12,16-PENTAMETHYL-3-[1-METHYL-2-(2-METHYL-THIAZOL-4-YL)VINYL]-4,17-DIOXABICYCLO[14.1.0]HEPTADECANE-5,9-DIONE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Moores, C.A, von Loeffelholz, O. | 登録日 | 2019-07-10 | 公開日 | 2019-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Cryo-EM Structure (4.5- angstrom ) of Yeast Kinesin-5-Microtubule Complex Reveals a Distinct Binding Footprint and Mechanism of Drug Resistance. J.Mol.Biol., 431, 2019
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6S8K
| Structure, Thermodynamics, and Kinetics of Plinabulin Binding to two Tubulin Isotypes | 分子名称: | (3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]piperazine-2,5-dione, Designed ankyrin repeat protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Sharma, A, Olieric, N, Steinmetz, M. | 登録日 | 2019-07-10 | 公開日 | 2019-11-27 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Structure, Thermodynamics, and Kinetics of Plinabulin Binding to Two Tubulin Isotypes Chem, 5, 2019
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6S8L
| Structure, Thermodynamics, and Kinetics of Plinabulin Binding to two Tubulin Isotypes | 分子名称: | (3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]piperazine-2,5-dione, Designed ankyrin repeat protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Sharma, A, Olieric, N, Steinmetz, M. | 登録日 | 2019-07-10 | 公開日 | 2019-11-27 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Structure, Thermodynamics, and Kinetics of Plinabulin Binding to Two Tubulin Isotypes Chem, 2019
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6K9V
| Crystal structure of tubulin in complex with inhibitor D64 | 分子名称: | (5-methoxy-1H-indol-2-yl)-phenyl-methanone, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Yu, Y, Chen, Q. | 登録日 | 2019-06-18 | 公開日 | 2019-08-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.543 Å) | 主引用文献 | Structural insights into the design of indole derivatives as tubulin polymerization inhibitors. Febs Lett., 594, 2020
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6PC4
| Tubulin-RB3_SLD-TTL in complex with compound ABI-274 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Kumar, G, Wang, Y, Li, W, White, S.W. | 登録日 | 2019-06-15 | 公開日 | 2020-04-22 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | 主引用文献 | Structure-Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties. J.Med.Chem., 63, 2020
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6RZB
| Cryo-EM structure of mouse cytoplasmic dynein-1 microtubule binding domain bound to microtubules | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Lacey, S.E, He, S, Scheres, S.H.W, Carter, A.P. | 登録日 | 2019-06-13 | 公開日 | 2019-07-10 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule. Elife, 8, 2019
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6RZA
| Cryo-EM structure of the human inner arm dynein DNAH7 microtubule binding domain bound to microtubules | 分子名称: | Cytoplasmic dynein 1 heavy chain 1,Dynein heavy chain 7, axonemal,Cytoplasmic dynein 1 heavy chain 1, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Lacey, S.E, He, S, Scheres, S.H.W, Carter, A.P. | 登録日 | 2019-06-13 | 公開日 | 2019-07-10 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule. Elife, 8, 2019
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6RVM
| Cell division protein FtsZ from Staphylococcus aureus, apo form | 分子名称: | CHLORIDE ION, Cell division protein FtsZ, GLYCEROL, ... | 著者 | Fernandez-Tornero, C, Andreu, J.M, Canosa-Valls, A.J. | 登録日 | 2019-05-31 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.155 Å) | 主引用文献 | Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus. Febs J., 287, 2020
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6RVQ
| SaFtsz-GDP-EthGLy | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Cell division protein FtsZ, ... | 著者 | Fernandez-Tornero, C, Andreu, J.M. | 登録日 | 2019-05-31 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.136 Å) | 主引用文献 | Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus. Febs J., 287, 2020
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6RVP
| SaFtsz-GDP-MetPyr | 分子名称: | 1-methylpyrrolidin-2-one, CALCIUM ION, Cell division protein FtsZ, ... | 著者 | Fernandez-Tornero, C, Andreu, J.M. | 登録日 | 2019-05-31 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | 主引用文献 | Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus. Febs J., 287, 2020
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6RVN
| aFtsz-GDP-Wat | 分子名称: | CALCIUM ION, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE | 著者 | Fernandez-Tornero, C, Andreu, J.M. | 登録日 | 2019-05-31 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.242 Å) | 主引用文献 | Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus. Febs J., 287, 2020
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6RFD
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6OJQ
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6RF8
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6RF2
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6REV
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