6SES

Tubulin-B2 complex

Summary for 6SES

• Entry DOI: 10.2210/pdb6ses/pdb
• Descriptor: Tubulin alpha-1B chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (12 entities in total)
• Functional Keywords: cell cycle, tubulin fold, cytoskeleton, microtubule
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 6
• Total formula weight: 265609.71

Authors

Guo, B.,Rodriguez-Gabin, A.,Prota, A.E.,Muehlethaler, T.,Zhang, N.,Ye, K.,Steinmetz, M.O.,Band Horwitz, S.,Smith III, A.B.,McDaid, H.M. (deposition date: 2019-07-30, release date: 2020-07-08, Last modification date: 2024-01-24)

• Primary citation: Guo, B.,Rodriguez-Gabin, A.,Prota, A.E.,Muhlethaler, T.,Zhang, N.,Ye, K.,Steinmetz, M.O.,Horwitz, S.B.,Smith 3rd, A.B.,McDaid, H.M.; Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence.; Mol.Pharmacol., 98:156-167, 2020; PubMed: 32591477; DOI: 10.1124/mol.119.117457

Experimental method

X-RAY DIFFRACTION (2 Å)