6S8K
Structure, Thermodynamics, and Kinetics of Plinabulin Binding to two Tubulin Isotypes
Summary for 6S8K
Entry DOI | 10.2210/pdb6s8k/pdb |
Descriptor | Tubulin alpha-1B chain, Tubulin beta-2B chain, Designed ankyrin repeat protein (DARPIN) D1, ... (8 entities in total) |
Functional Keywords | tubulin, microtubules, microtubule targeting agents, cancer, structural protein |
Biological source | synthetic construct More |
Total number of polymer chains | 3 |
Total formula weight | 116427.63 |
Authors | Sharma, A.,Olieric, N.,Steinmetz, M. (deposition date: 2019-07-10, release date: 2019-11-27, Last modification date: 2024-05-15) |
Primary citation | La Sala, G.,Olieric, N.,Sharma, A. Structure, Thermodynamics, and Kinetics of Plinabulin Binding to Two Tubulin Isotypes Chem, 5:-, 2019 Cited by DOI: 10.1016/j.chempr.2019.08.022PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.52 Å) |
Structure validation
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