6RF2

Cryo-EM structure of the C-terminal DC repeat (CDC) of human doublecortin (DCX) bound to 13-protofilament GDP.Pi-microtubule

Summary for 6RF2

• Entry DOI: 10.2210/pdb6rf2/pdb
• EMDB information: 4861
• Descriptor: Tubulin alpha-1B chain, Tubulin beta-2B chain, Neuronal migration protein doublecortin, ... (7 entities in total)
• Functional Keywords: microtubule-associated protein, neuronal migration protein, microtubule nucleation and stabilisation, cytosolic protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 204825.26

Authors

Manka, S.W. (deposition date: 2019-04-12, release date: 2020-05-13, Last modification date: 2021-03-03)

• Primary citation: Manka, S.W.,Moores, C.A.; Pseudo-repeats in doublecortin make distinct mechanistic contributions to microtubule regulation.; Embo Rep., 21:e51534-e51534, 2020; PubMed: 33051979; DOI: 10.15252/embr.202051534

Experimental method

ELECTRON MICROSCOPY (4.2 Å)