PDB: 594 件ウェブページステータス検索Chemie searchBIRD

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2RVF	Solution NMR structure of Monosiga brevicollis CRK/CRKL homolog (crka1) SH2 domain 分子名称: Predicted protein 著者 Kasai, T, Pawlak, J, Imamoto, A, Kigawa, T. 登録日 2015-09-24 公開日 2016-09-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 A pre-metazoan origin of the CRK gene family and co-opted signaling network Sci Rep, 6, 2016
2RSY	Solution structure of the SH2 domain of Csk in complex with a phosphopeptide from Cbp 分子名称: Phosphoprotein associated with glycosphingolipid-enriched microdomains 1, Tyrosine-protein kinase CSK 著者 Tanaka, H, Akagi, K, Oneyama, C, Tanaka, M, Sasaki, Y, Kanou, T, Lee, Y, Yokogawa, D, Debenecker, M, Nakagawa, A, Okada, M, Ikegami, T. 登録日 2012-09-10 公開日 2013-04-10 最終更新日 2019-12-25 実験手法 SOLUTION NMR 主引用文献 Identification of a new interaction mode between the Src homology 2 domain of C-terminal Src kinase (Csk) and Csk-binding protein/phosphoprotein associated with glycosphingolipid microdomains. J.Biol.Chem., 288, 2013
2ROR	Solution structure of the VAV1 SH2 domain complexed with a tyrosine-phosphorylated peptide from SLP76 分子名称: 15-meric peptide from Lymphocyte cytosolic protein 2, Proto-oncogene vav 著者 Tanaka, M, Kasai, T, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2008-04-08 公開日 2009-04-21 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of the VAV1 SH2 domain complexed with a tyrosine-phosphorylated peptide from SLP76 To be Published
2RMX	Solution structure of the SHP-1 C-terminal SH2 domain complexed with a tyrosine-phosphorylated peptide from NKG2A 分子名称: NKG2-A/NKG2-B type II integral membrane protein, Tyrosine-protein phosphatase non-receptor type 6 著者 Kasai, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-11-30 公開日 2008-12-02 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Structural basis for the recognition of the two NKG2A immunoreceptor tyrosine-based inhibitory motifs (ITIMs) by the C-terminal SH2 domain of protein tyrosine phosphatase SHP-1 To be Published
2RD0	Structure of a human p110alpha/p85alpha complex 分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 著者 Huang, C, Gabelli, S.B, Amzel, L.M. 登録日 2007-09-20 公開日 2007-12-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations. Science, 318, 2007
2QMS	Crystal structure of a signaling molecule 分子名称: Growth factor receptor-bound protein 7, SULFATE ION 著者 Porter, C.J, Wilce, M.C, Wilce, J.A. 登録日 2007-07-16 公開日 2008-07-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation. Bmc Struct.Biol., 7, 2007
2PTK	CHICKEN SRC TYROSINE KINASE 分子名称: TYROSINE-PROTEIN KINASE TRANSFORMING PROTEIN SRC 著者 Williams, J.C, Wierenga, R. 登録日 1997-06-17 公開日 1997-12-24 最終更新日 2018-04-11 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The 2.35 A crystal structure of the inactivated form of chicken Src: a dynamic molecule with multiple regulatory interactions J.Mol.Biol., 274, 1997
2PNB	STRUCTURE OF AN SH2 DOMAIN OF THE P85 ALPHA SUBUNIT OF PHOSPHATIDYLINOSITOL-3-OH KINASE 分子名称: PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT N-TERMINAL SH2 DOMAIN 著者 Booker, G.W, Breeze, A.L, Downing, A.K, Panayotou, G, Gout, I, Waterfield, M.D, Campbell, I.D. 登録日 1992-06-30 公開日 1994-01-31 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structure of an SH2 domain of the p85 alpha subunit of phosphatidylinositol-3-OH kinase. Nature, 358, 1992
2PNA	STRUCTURE OF AN SH2 DOMAIN OF THE P85 ALPHA SUBUNIT OF PHOSPHATIDYLINOSITOL-3-OH KINASE 分子名称: PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT N-TERMINAL SH2 DOMAIN 著者 Booker, G.W, Breeze, A.L, Downing, A.K, Panayotou, G, Gout, I, Waterfield, M.D, Campbell, I.D. 登録日 1992-06-30 公開日 1994-01-31 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structure of an SH2 domain of the p85 alpha subunit of phosphatidylinositol-3-OH kinase. Nature, 358, 1992
2PLE	NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE 分子名称: PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF 著者 Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D. 登録日 1994-08-19 公開日 1995-01-26 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide. Cell(Cambridge,Mass.), 77, 1994
2PLD	NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE 分子名称: PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF 著者 Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D. 登録日 1994-08-19 公開日 1995-01-26 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide. Cell(Cambridge,Mass.), 77, 1994
2OZO	Autoinhibited intact human ZAP-70 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Tyrosine-protein kinase ZAP-70 著者 Deindl, S, Kadlecek, T.A, Brdicka, T, Cao, X, Weiss, A, Kuriyan, J. 登録日 2007-02-26 公開日 2007-05-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Basis for the Inhibition of Tyrosine Kinase Activity of ZAP-70. Cell(Cambridge,Mass.), 129, 2007
2OQ1	Tandem SH2 domains of ZAP-70 with 19-mer zeta1 peptide 分子名称: LEAD (II) ION, T-cell surface glycoprotein CD3 zeta chain, Tyrosine-protein kinase ZAP-70 著者 Hatada, M.H, Laird, E.R, Green, J, Morgenstern, J, Ram, M.K. 登録日 2007-01-30 公開日 2007-03-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular basis for the interaction of ZAP-70 with the T-cell receptor Nature, 377, 1995
2MRK	Fyn SH2 domain in complex with the natural inhibitory phosphotyrosine peptide 分子名称: C-terminal Tyrosine-protein kinase Fyn, Tyrosine-protein kinase Fyn 著者 Huculeci, R, Buts, L, Lenaerts, A.J, van Nuland, N. 登録日 2014-07-09 公開日 2015-07-15 最終更新日 2016-12-14 実験手法 SOLUTION NMR 主引用文献 Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity. Structure, 24, 2016
2MRJ	Structure of Fyn protein SH2 bound 分子名称: Tyrosine-protein kinase Fyn 著者 Huculeci, R, Buts, L, Lenaerts, T, Van Nuland, N. 登録日 2014-07-09 公開日 2015-07-15 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity. Structure, 24, 2016
2MQI	human Fyn SH2 free state 分子名称: Tyrosine-protein kinase Fyn 著者 Huculeci, R, Buts, L, Lenaerts, T, VanNuland, N. 登録日 2014-06-20 公開日 2015-07-29 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity. Structure, 24, 2016
2MK2	Solution NMR structure of N-terminal domain (SH2 domain) of human Inositol polyphosphate phosphatase-like protein 1 (INPPL1) (fragment 20-117), Northeast Structural Genomics Consortium Target HR9134A 分子名称: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 著者 Yang, Y, Ramelot, T.A, Janjua, H, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) 登録日 2014-01-23 公開日 2014-03-05 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution NMR structure of N-terminal domain (SH2 domain) of human Inositol polyphosphate phosphatase-like protein 1 (INPPL1) (fragment 20-117), Northeast Structural Genomics Consortium Target HR9134A. To be Published
2MC1	Solution structure of the Vav1 SH2 domain complexed with a Syk-derived singly phosphorylated peptide 分子名称: Proto-oncogene vav, Tyrosine-protein kinase SYK 著者 Chen, C, Piraner, D, Gorenstein, N.M, Geahlen, R.L, Post, C.B. 登録日 2013-08-13 公開日 2013-08-28 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Differential recognition of syk-binding sites by each of the two phosphotyrosine-binding pockets of the Vav SH2 domain. Biopolymers, 99, 2013
2LQW	Solution structure of phosphorylated CRKL 分子名称: Crk-like protein 著者 Jankowski, W, Saleh, T, Kalodimos, C. 登録日 2012-03-16 公開日 2012-05-16 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII. Nat.Chem.Biol., 8, 2012
2LQN	Solution structure of CRKL 分子名称: Crk-like protein 著者 Jankowski, W, Saleh, T, Kalodimos, C. 登録日 2012-03-09 公開日 2012-05-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII. Nat.Chem.Biol., 8, 2012
2LNX	Solution structure of Vav2 SH2 domain 分子名称: Guanine nucleotide exchange factor VAV2 著者 Wu, B, Zhang, J, Wu, J, Shi, Y. 登録日 2012-01-05 公開日 2012-11-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Identification and structural basis for a novel interaction between Vav2 and Arap3. J.Struct.Biol., 180, 2012
2LNW	Identification and structural basis for a novel interaction between Vav2 and Arap3 分子名称: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3, Guanine nucleotide exchange factor VAV2 著者 Wu, B, Zhang, J, Wu, J, Shi, Y. 登録日 2012-01-05 公開日 2012-11-21 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Identification and structural basis for a novel interaction between Vav2 and Arap3. J.Struct.Biol., 180, 2012
2LCT	Solution structure of the Vav1 SH2 domain complexed with a Syk-derived doubly phosphorylated peptide 分子名称: Proto-oncogene vav, Tyrosine-protein kinase SYK 著者 Chen, C, Gorenstein, N, Post, C. 登録日 2011-05-09 公開日 2011-06-01 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav. Mol.Cell.Biol., 31, 2011
2L6K	Solution Structure of a Nonphosphorylated Peptide Recognizing Domain 分子名称: Tensin-like C1 domain-containing phosphatase 著者 Dai, K, Liao, S, Zhang, J, Zhang, X, Tu, X. 登録日 2010-11-22 公開日 2011-10-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structure of Tensin2 SH2 domain and its phosphotyrosine-independent interaction with DLC-1 Plos One, 6, 2011
2L4K	Water refined solution structure of the human Grb7-SH2 domain in complex with the 10 amino acid peptide pY1139 分子名称: Growth factor receptor-bound protein 7, Receptor tyrosine-protein kinase erbB-2 著者 Pias, S.C, Ivancic, M, Brescia, P.J, Johnson, D.L, Smith, D.E, Daly, R.J, Lyons, B.A. 登録日 2010-10-07 公開日 2010-11-17 最終更新日 2012-10-03 実験手法 SOLUTION NMR 主引用文献 Water-Refined Solution Structure of the Human Grb7-SH2 Domain in Complex with the erbB2 Receptor Peptide pY1139. Protein Pept.Lett., 19, 2012

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