2ROR

Solution structure of the VAV1 SH2 domain complexed with a tyrosine-phosphorylated peptide from SLP76

Summary for 2ROR

DescriptorProto-oncogene vav, 15-meric peptide from Lymphocyte cytosolic protein 2 (2 entities in total)
Functional Keywordssh2 domain, protein-peptide complex, phosphorylated peptide recognition, phosphotyrosine binding domain, signal transduction, guanine-nucleotide releasing factor, metal-binding, phorbol-ester binding, phosphoprotein, proto-oncogene, sh3 domain, zinc, zinc-finger, signaling protein, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm (Probable) Q13094
Total number of polymer chains2
Total molecular weight17289.93
Authors
Tanaka, M.,Kasai, T.,Koshiba, S.,Kigawa, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2008-04-08, release date: 2009-04-21, Last modification date: 2011-07-13)
Primary citation
Kasai, T.,Tanaka, M.,Koshiba, S.,Kigawa, T.,Yokoyama, S.
Solution structure of the VAV1 SH2 domain complexed with a tyrosine-phosphorylated peptide from SLP76
To be Published,
Experimental method
SOLUTION NMR
NMR Information
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers253.1%9.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation report