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5CUS
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BU of 5cus by Molmil
Crystal Structure of sErbB3-Fab3379 Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab LC region of KTN3379, IgG H chain, ...
著者Lee, S, Schlessinger, J.
登録日2015-07-25
公開日2015-10-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Inhibition of ErbB3 by a monoclonal antibody that locks the extracellular domain in an inactive configuration.
Proc.Natl.Acad.Sci.USA, 112, 2015
5D1X
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BU of 5d1x by Molmil
IsdB NEAT2 bound by D4-30
分子名称: D4-30 Heavy Chain, D4-30 Light Chain, Iron-regulated surface determinant protein B, ...
著者Deng, X.
登録日2015-08-04
公開日2016-08-10
最終更新日2016-12-07
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire.
Nat Commun, 7, 2016
1DEE
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BU of 1dee by Molmil
Structure of S. aureus protein A bound to a human IgM Fab
分子名称: IGM RF 2A2, IMMUNOGLOBULIN G BINDING PROTEIN A
著者Graille, M, Stura, E.A, Corper, A.L, Sutton, B.J, Taussig, M.J, Charbonnier, J.B, Silverman, G.J.
登録日1999-11-15
公開日2000-05-24
最終更新日2018-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: structural basis for recognition of B-cell receptors and superantigen activity.
Proc.Natl.Acad.Sci.USA, 97, 2000
4I0C
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BU of 4i0c by Molmil
The structure of the camelid antibody cAbHuL5 in complex with human lysozyme
分子名称: CHLORIDE ION, GLYCEROL, Lysozyme C, ...
著者De Genst, E, Chan, P.H, Pardon, E, Kumita, J.R, Christodoulou, J, Menzer, L, Chirgadze, D.Y, Robinson, C.V, Muyldermans, S, Matagne, A, Wyns, L, Dobson, C.M, Dumoulin, M.
登録日2012-11-16
公開日2013-10-09
最終更新日2013-11-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.
J.Phys.Chem.B, 117, 2013
4EJ1
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BU of 4ej1 by Molmil
Binding of Nb113 camelid antibody fragment with the binary DHFR:folate complex
分子名称: Dihydrofolate reductase, FOLIC ACID, Nb113 camelid antibody fragment, ...
著者Oyen, D, Srinivasan, V.
登録日2012-04-06
公開日2013-04-24
最終更新日2013-10-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli.
Biochim.Biophys.Acta, 1834, 2013
5VQM
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BU of 5vqm by Molmil
Clostridium difficile TcdB-GTD bound to PA41 Fab
分子名称: PA41 FAB HEAVY CHAIN, PA41 FAB LIGHT CHAIN, Toxin B
著者Kroh, H.K, Spiller, B.W, Lacy, D.B.
登録日2017-05-09
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献A neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells.
J. Biol. Chem., 293, 2018
8G3V
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BU of 8g3v by Molmil
N2 neuraminidase of A/Hong_Kong/2671/2019 in complex with 4 FNI19 Fab molecules
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Dang, H.V, Snell, G.
登録日2023-02-08
公開日2023-05-31
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (2.21 Å)
主引用文献A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
Nature, 618, 2023
8G3Z
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Neuraminidase of B/Massachusetts/02/2012 (Yamagata) in complex with 4 FNI17 Fab molecules
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FNI17 Fab heavy chain, ...
著者Dang, H.V, Snell, G.
登録日2023-02-08
公開日2023-05-31
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
Nature, 618, 2023
8G3O
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BU of 8g3o by Molmil
N2 neuraminidase of A/Hong_Kong/2671/2019 in complex with 3 FNI9 Fab molecules
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Dang, H.V, Snell, G.
登録日2023-02-08
公開日2023-05-31
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
Nature, 618, 2023
8G3R
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BU of 8g3r by Molmil
N2 neuraminidase of A/Tanzania/205/2010 H3N2 with S245N S247T mutations in complex with one FNI17 Fab molecule
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Dang, H.V, Snell, G.
登録日2023-02-08
公開日2023-05-31
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
Nature, 618, 2023
8G3M
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BU of 8g3m by Molmil
N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with 3 FNI9 Fab molecules
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FNI9 Fab heavy chain, ...
著者Dang, H.V, Snell, G.
登録日2023-02-08
公開日2023-05-31
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
Nature, 618, 2023
8G40
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BU of 8g40 by Molmil
N2 neuraminidase of A/Hong_Kong/2671/2019 in complex with 3 FNI19 Fab molecules
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Dang, H.V, Snell, G.
登録日2023-02-08
公開日2023-05-31
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
Nature, 618, 2023
8G3P
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BU of 8g3p by Molmil
N2 neuraminidase of A/Hong_Kong/2671/2019 in complex with 4 FNI9 Fab molecules
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Dang, H.V, Snell, G.
登録日2023-02-08
公開日2023-05-31
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
Nature, 618, 2023
1MFE
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BU of 1mfe by Molmil
RECOGNITION OF A CELL-SURFACE OLIGO-SACCHARIDE OF PATHOGENIC SALMONELLA BY AN ANTIBODY FAB FRAGMENT
分子名称: IGG1-LAMBDA SE155-4 FAB (HEAVY CHAIN), IGG1-LAMBDA SE155-4 FAB (LIGHT CHAIN), alpha-D-galactopyranose-(1-2)-[alpha-D-Abequopyranose-(1-3)]alpha-D-mannopyranose
著者Cygler, M.
登録日1993-10-25
公開日1994-01-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Recognition of a cell-surface oligosaccharide of pathogenic Salmonella by an antibody Fab fragment.
Science, 253, 1991
3P0Y
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BU of 3p0y by Molmil
anti-EGFR/HER3 Fab DL11 in complex with domain III of EGFR extracellular region
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
著者Eigenbrot, C, Shia, S.
登録日2010-09-29
公開日2011-10-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.
Cancer Cell, 20, 2011
3P0V
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BU of 3p0v by Molmil
anti-EGFR/HER3 Fab DL11 alone
分子名称: CALCIUM ION, Fab DL11 heavy chain, Fab DL11 light chain
著者Eigenbrot, C, Shia, S.
登録日2010-09-29
公開日2011-10-19
最終更新日2012-03-21
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.
Cancer Cell, 20, 2011
6O1F
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BU of 6o1f by Molmil
Complex between soybean trypsin inhibitor beta1-tryptase and a humanized fab
分子名称: 1,2-ETHANEDIOL, Heavy Chain hu31A.v11, Light Chain hu31A.v11, ...
著者Ultsch, M.H, Yi, T.
登録日2019-02-19
公開日2019-10-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
Cell, 179, 2019
6AD1
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BU of 6ad1 by Molmil
The structure of CVA10 procapsid from its complex with Fab 2G8
分子名称: VP0, VP1, VP3
著者Zhu, R, Zheng, Q.B, Xu, L.F, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T.
登録日2018-07-28
公開日2018-11-21
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
6AD0
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BU of 6ad0 by Molmil
The structure of CVA10 mature virion in complex with Fab 2G8
分子名称: SPHINGOSINE, VH of Fab 2G8, VL of Fab 2G8, ...
著者Zhu, R, Zheng, Q.B, Xu, L.F, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T.
登録日2018-07-28
公開日2018-11-21
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
6OUS
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BU of 6ous by Molmil
Structure of fusion glycoprotein from human respiratory syncytial virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, ...
著者Su, H.P.
登録日2019-05-05
公開日2019-10-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein.
Nat Commun, 10, 2019
7PA6
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BU of 7pa6 by Molmil
JC polyomavirus VP1 in complex with scFv 27C11
分子名称: Major capsid protein VP1, scFv 27C11 antibody heavy chain
著者Harprecht, C, Stroeh, L.J, Nagel, F, Freytag, J, Stehle, T.
登録日2021-07-29
公開日2023-02-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural characterization of human neutralizing antibodies against JC and BK polyomavirus
To Be Published
7PA7
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BU of 7pa7 by Molmil
BK polyomavirus VP1 in complex with scFv 29B1
分子名称: Major capsid protein VP1, scFv 29B1 antibody heavy chain
著者Harprecht, C, Stroeh, L.J, Freytag, J, Stehle, T.
登録日2021-07-29
公開日2023-02-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural characterization of human neutralizing antibodies against JC and BK polyomavirus
To Be Published
6ACZ
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BU of 6acz by Molmil
The structure of CVA10 virus A-particle from its complex with Fab 2G8
分子名称: VP1, VP2, VP3
著者Zhu, R, Zheng, Q.B, Xu, L.F, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T.
登録日2018-07-28
公開日2018-11-21
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
5TDN
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BU of 5tdn by Molmil
Crystal structure of the Fab fragment of anti-HER2 antibody 4D5 with redesigned heavy and light chain interfaces
分子名称: GLYCEROL, anti-HER2 Fab Heavy Chain, anti-HER2 Fab Light Chain
著者Yin, Y, Carter, P.J.
登録日2016-09-19
公開日2016-12-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Crystal structure of the Fab fragment of anti-HER2 antibody 4D5 with redesigned heavy and light chain interfaces
To Be Published
8Q5Y
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BU of 8q5y by Molmil
cryoEM structure of SARS-CoV2 Spike trimer in complex with Fab23
分子名称: Monoclonal antibody Mab 23 (Heavy Chain), Monoclonal antibody Mab 23 (Light chain), Spike glycoprotein
著者Hallberg, M, Das, H.
登録日2023-08-10
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Multi-compartmental diversification of neutralizing antibody lineages dissected in SARS-CoV-2 spike-immunized macaques
Nature Communications, 2024

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