8G40

N2 neuraminidase of A/Hong_Kong/2671/2019 in complex with 3 FNI19 Fab molecules

Summary for 8G40

• Entry DOI: 10.2210/pdb8g40/pdb
• Related: 8G3V
• EMDB information: 29710 29712
• Descriptor: Neuraminidase, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (11 entities in total)
• Functional Keywords: viral glycoprotein, antibody, fab, influenza, virus, viral protein-immune system complex, viral protein/immune system
• Biological source: Influenza A virus; More
• Total number of polymer chains: 10
• Total formula weight: 380401.43

Authors

Dang, H.V.,Snell, G. (deposition date: 2023-02-08, release date: 2023-05-31, Last modification date: 2023-06-28)

• Primary citation: Momont, C.,Dang, H.V.,Zatta, F.,Hauser, K.,Wang, C.,di Iulio, J.,Minola, A.,Czudnochowski, N.,De Marco, A.,Branch, K.,Donermeyer, D.,Vyas, S.,Chen, A.,Ferri, E.,Guarino, B.,Powell, A.E.,Spreafico, R.,Yim, S.S.,Balce, D.R.,Bartha, I.,Meury, M.,Croll, T.I.,Belnap, D.M.,Schmid, M.A.,Schaiff, W.T.,Miller, J.L.,Cameroni, E.,Telenti, A.,Virgin, H.W.,Rosen, L.E.,Purcell, L.A.,Lanzavecchia, A.,Snell, G.,Corti, D.,Pizzuto, M.S.; A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.; Nature, 618:590-597, 2023; PubMed: 37258672; DOI: 10.1038/s41586-023-06136-y

Experimental method

ELECTRON MICROSCOPY (2.8 Å)