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8G3Z

Neuraminidase of B/Massachusetts/02/2012 (Yamagata) in complex with 4 FNI17 Fab molecules

Summary for 8G3Z
Entry DOI10.2210/pdb8g3z/pdb
Related8G30
EMDB information29686 29711
DescriptorFNI17 Fab heavy chain, FNI17 Fab light chain, Neuraminidase, ... (5 entities in total)
Functional Keywordsviral glycoprotein, antibody, fab, influenza, virus, viral protein-immune system complex, viral protein/immune system
Biological sourceHomo sapiens
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Total number of polymer chains12
Total formula weight414790.64
Authors
Dang, H.V.,Snell, G. (deposition date: 2023-02-08, release date: 2023-05-31, Last modification date: 2023-06-28)
Primary citationMomont, C.,Dang, H.V.,Zatta, F.,Hauser, K.,Wang, C.,di Iulio, J.,Minola, A.,Czudnochowski, N.,De Marco, A.,Branch, K.,Donermeyer, D.,Vyas, S.,Chen, A.,Ferri, E.,Guarino, B.,Powell, A.E.,Spreafico, R.,Yim, S.S.,Balce, D.R.,Bartha, I.,Meury, M.,Croll, T.I.,Belnap, D.M.,Schmid, M.A.,Schaiff, W.T.,Miller, J.L.,Cameroni, E.,Telenti, A.,Virgin, H.W.,Rosen, L.E.,Purcell, L.A.,Lanzavecchia, A.,Snell, G.,Corti, D.,Pizzuto, M.S.
A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
Nature, 618:590-597, 2023
Cited by
PubMed: 37258672
DOI: 10.1038/s41586-023-06136-y
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.3 Å)
Structure validation

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