8G3Z

Neuraminidase of B/Massachusetts/02/2012 (Yamagata) in complex with 4 FNI17 Fab molecules

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G (H, E, G, J)	FNI17 Fab heavy chain	polymer	231	24580.5	4		Homo sapiens
2	B, D, F, H (L, F, I, K)	FNI17 Fab light chain	polymer	215	23479.1	4		Homo sapiens
3	I, J, K, L (A, B, C, D)	Neuraminidase	polymer	496	55145.6	4	UniProt (A0A0D6A730) Pfam (PF00064) UniProt (by SIFTS) (R4KV67)	Influenza B virus
4	M, P, Q, T, W (A, B, C, D)	CALCIUM ION	non-polymer		40.1	5	Chemie (CA)
5	N, O, R, S, U... (A, B, C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG)

Sequence modifications

A, B, C, D: 75 - 466 (UniProt: A0A0D6A730)

PDB	External Database	Details
Met -29	-	initiating methionine
Glu -28	-	expression tag
Thr -27	-	expression tag
Asp -26	-	expression tag
Thr -25	-	expression tag
Leu -24	-	expression tag
Leu -23	-	expression tag
Leu -22	-	expression tag
Trp -21	-	expression tag
Val -20	-	expression tag
Leu -19	-	expression tag
Leu -18	-	expression tag
Leu -17	-	expression tag
Trp -16	-	expression tag
Val -15	-	expression tag
Pro -14	-	expression tag
Gly -13	-	expression tag
Ser -12	-	expression tag
Thr -11	-	expression tag
Gly -10	-	expression tag
Asp -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag
Leu 1	-	expression tag
Asn 2	-	expression tag
Asp 3	-	expression tag
Ile 4	-	expression tag
Phe 5	-	expression tag
Glu 6	-	expression tag
Ala 7	-	expression tag
Gln 8	-	expression tag
Lys 9	-	expression tag
Ile 10	-	expression tag
Glu 11	-	expression tag
Trp 12	-	expression tag
His 13	-	expression tag
Glu 14	-	expression tag
Gly 15	-	expression tag
Ser 16	-	expression tag
Ile 17	-	expression tag
Ile 18	-	expression tag
Asn 19	-	expression tag
Glu 20	-	expression tag
Thr 21	-	expression tag
Ala 22	-	expression tag
Asp 23	-	expression tag
Asp 24	-	expression tag
Ile 25	-	expression tag
Val 26	-	expression tag
Tyr 27	-	expression tag
Arg 28	-	expression tag
Leu 29	-	expression tag
Thr 30	-	expression tag
Val 31	-	expression tag
Ile 32	-	expression tag
Ile 33	-	expression tag
Asp 34	-	expression tag
Asp 35	-	expression tag
Arg 36	-	expression tag
Tyr 37	-	expression tag
Glu 38	-	expression tag
Ser 39	-	expression tag
Leu 40	-	expression tag
Lys 41	-	expression tag
Asn 42	-	expression tag
Leu 43	-	expression tag
Ile 44	-	expression tag
Thr 45	-	expression tag
Leu 46	-	expression tag
Arg 47	-	expression tag
Ala 48	-	expression tag
Asp 49	-	expression tag
Arg 50	-	expression tag
Leu 51	-	expression tag
Glu 52	-	expression tag
Met 53	-	expression tag
Ile 54	-	expression tag
Ile 55	-	expression tag
Asn 56	-	expression tag
Asp 57	-	expression tag
Asn 58	-	expression tag
Val 59	-	expression tag
Ser 60	-	expression tag
Thr 61	-	expression tag
Ile 62	-	expression tag
Leu 63	-	expression tag
Ala 64	-	expression tag
Ser 65	-	expression tag
Gly 66	-	expression tag
Leu 67	-	expression tag
Val 68	-	expression tag
Pro 69	-	expression tag
Arg 70	-	expression tag
Gly 71	-	expression tag
Ser 72	-	expression tag
Gly 73	-	expression tag
Ser 74	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	412820.6
Non-Polymers*	Number of molecules	13
	Total formula weight	1970.1
All*	Total formula weight	414790.6

*Water molecules are not included.