1DEE

Structure of S. aureus protein A bound to a human IgM Fab

Summary for 1DEE

Entry DOI	10.2210/pdb1dee/pdb
Descriptor	IGM RF 2A2, IMMUNOGLOBULIN G BINDING PROTEIN A, ... (4 entities in total)
Functional Keywords	fab-ibp complex crystal structure 2.7a resolution binding outside the antigen combining site superantigen fab vh3 specificity, immune system
Biological source	Staphylococcus aureus More
Cellular location	Secreted, cell wall ; Peptidoglycan-anchor : P02976
Total number of polymer chains	8
Total formula weight	154739.95
Authors	Graille, M.,Stura, E.A.,Corper, A.L.,Sutton, B.J.,Taussig, M.J.,Charbonnier, J.B.,Silverman, G.J. (deposition date: 1999-11-15, release date: 2000-05-24, Last modification date: 2018-02-14)
Primary citation	Graille, M.,Stura, E.A.,Corper, A.L.,Sutton, B.J.,Taussig, M.J.,Charbonnier, J.B.,Silverman, G.J. Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: structural basis for recognition of B-cell receptors and superantigen activity. Proc.Natl.Acad.Sci.USA, 97:5399-5404, 2000 Cited by PubMed: 10805799 DOI: 10.1073/pnas.97.10.5399 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation