5VQM
Clostridium difficile TcdB-GTD bound to PA41 Fab
Summary for 5VQM
Entry DOI | 10.2210/pdb5vqm/pdb |
Descriptor | Toxin B, PA41 FAB LIGHT CHAIN, PA41 FAB HEAVY CHAIN, ... (4 entities in total) |
Functional Keywords | toxin antibody, toxin-immune system complex, toxin/immune system |
Biological source | Peptoclostridium difficile (Clostridium difficile) More |
Total number of polymer chains | 6 |
Total formula weight | 223373.91 |
Authors | Kroh, H.K.,Spiller, B.W.,Lacy, D.B. (deposition date: 2017-05-09, release date: 2017-12-06, Last modification date: 2023-10-04) |
Primary citation | Kroh, H.K.,Chandrasekaran, R.,Zhang, Z.,Rosenthal, K.,Woods, R.,Jin, X.,Nyborg, A.C.,Rainey, G.J.,Warrener, P.,Melnyk, R.A.,Spiller, B.W.,Lacy, D.B. A neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells. J. Biol. Chem., 293:941-952, 2018 Cited by PubMed: 29180448DOI: 10.1074/jbc.M117.813428 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.79 Å) |
Structure validation
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