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8SPX
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BU of 8spx by Molmil
PS3 F1 Rotorless, high ATP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ...
著者Sobti, M, Stewart, A.G.
登録日2023-05-03
公開日2024-01-24
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献The series of conformational states adopted by rotorless F 1 -ATPase during its hydrolysis cycle.
Structure, 32, 2024
8SPW
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BU of 8spw by Molmil
PS3 F1 Rotorless, low ATP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ...
著者Sobti, M, Stewart, A.G.
登録日2023-05-03
公開日2024-01-24
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The series of conformational states adopted by rotorless F 1 -ATPase during its hydrolysis cycle.
Structure, 32, 2024
8SPV
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BU of 8spv by Molmil
PS3 F1 Rotorless, no ATP
分子名称: ATP synthase subunit alpha, ATP synthase subunit beta
著者Sobti, M, Stewart, A.G.
登録日2023-05-03
公開日2024-01-24
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献The series of conformational states adopted by rotorless F 1 -ATPase during its hydrolysis cycle.
Structure, 32, 2024
8SPU
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BU of 8spu by Molmil
Structure of ESRRB nucleosome bound OCT4 at site c
分子名称: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2023-05-03
公開日2023-06-28
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
8SPS
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BU of 8sps by Molmil
High resolution structure of ESRRB nucleosome bound OCT4 at site a and site b
分子名称: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2023-05-03
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
8SPR
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BU of 8spr by Molmil
The cryo-EM structure of the EcBAM/EspP(beta1-12) complex
分子名称: Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ...
著者Wu, R, Noinaj, N.
登録日2023-05-03
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献BAM orchestrates OMP biogenesis using a beta-templating mechanism
To Be Published
8SPQ
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BU of 8spq by Molmil
SpRY-Cas9:gRNA complex targeting TGG PAM DNA
分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ...
著者Hibshman, G.N, Bravo, J.P.K, Taylor, D.W.
登録日2023-05-03
公開日2024-05-01
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
8SPP
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BU of 8spp by Molmil
Crystal structure of a heme enzyme RufO in rufomycin biosynthesis
分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
著者Wang, Y, Jordan, S, Li, B.
登録日2023-05-03
公開日2023-08-23
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structural and spectroscopic characterization of RufO indicates a new biological role in rufomycin biosynthesis.
J.Biol.Chem., 299, 2023
8SPO
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BU of 8spo by Molmil
Tetramerized activation of MapSPARTA bound with NAD+
分子名称: MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Piwi domain-containing protein, ...
著者Shen, Z.F, Yang, X.Y, Fu, T.M.
登録日2023-05-03
公開日2023-08-23
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Oligomerization-mediated activation of a short prokaryotic Argonaute.
Nature, 621, 2023
8SPN
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BU of 8spn by Molmil
Crystal structure of macrophage migration inhibitory factor in complex with T614
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Iguratimod, ...
著者Pantouris, G, Lolis, E.
登録日2023-05-03
公開日2024-05-01
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Iguratimod, an allosteric inhibitor of macrophage migration inhibitory factor (MIF), prevents mortality and oxidative stress in a murine model of acetaminophen overdose.
Mol Med, 30, 2024
8SPM
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BU of 8spm by Molmil
Crystal structure of NikA in complex Ni-AMA
分子名称: Aspergillomarasmine A, NICKEL (II) ION, Nickel ABC transporter, ...
著者Sychantha, D, Prehna, G, Wright, G.D.
登録日2023-05-03
公開日2024-04-10
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Targeting bacterial nickel transport with aspergillomarasmine A suppresses virulence-associated Ni-dependent enzymes.
Nat Commun, 15, 2024
8SPL
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BU of 8spl by Molmil
Proteinase K Multiconformer Model at 343K
分子名称: ALA-ALA-ALA-SER-VAL-LYS, CALCIUM ION, Proteinase K, ...
著者Du, S, Wankowicz, S, Yabukarski, F, Doukov, T, Herschlag, D, Fraser, J.S.
登録日2023-05-03
公開日2023-08-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Refinement of multiconformer ensemble models from multi-temperature X-ray diffraction data.
Methods Enzymol., 688, 2023
8SPK
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BU of 8spk by Molmil
Crystal structure of Antarctic PET-degrading enzyme
分子名称: Lipase 1, MALONATE ION
著者Furtado, A.A, Blazquez-Sanchez, P, Grinen, A, Vargas, J.A, Leonardo, D.A, Sculaccio, S.A, Pereira, H.M, Diez, B, Garratt, R.C, Ramirez-Sarmiento, C.A.
登録日2023-05-03
公開日2023-08-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Engineering the catalytic activity of an Antarctic PET-degrading enzyme by loop exchange.
Protein Sci., 32, 2023
8SPJ
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BU of 8spj by Molmil
Crystal Structure of SARS-CoV-2 Main Protease (Mpro) N28T Mutant
分子名称: 3C-like proteinase nsp5
著者Kohaal, N, Lewandowski, E.M, Wang, J, Chen, Y.
登録日2023-05-03
公開日2023-05-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Crystal Structure of SARS-CoV-2 Main Protease (Mpro) N28T Mutant
To Be Published
8SPI
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BU of 8spi by Molmil
Crystal structure of chimeric omicron RBD (strain XBB.1.5) complexed with human ACE2
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhang, W, Shi, K, Aihara, H, Li, F.
登録日2023-05-03
公開日2023-08-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Structural evolution of SARS-CoV-2 omicron in human receptor recognition.
J.Virol., 97, 2023
8SPH
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BU of 8sph by Molmil
Crystal structure of chimeric omicron RBD (strain XBB.1) complexed with human ACE2
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhang, W, Shi, K, Aihara, H, Li, F.
登録日2023-05-03
公開日2023-08-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural evolution of SARS-CoV-2 omicron in human receptor recognition.
J.Virol., 97, 2023
8SPF
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BU of 8spf by Molmil
Crystal structure of Bax core domain BH3-groove dimer - hexameric fraction with 2-stearoyl lysoPC
分子名称: 1,2-ETHANEDIOL, Apoptosis regulator BAX, DODECANE, ...
著者Cowan, A.D, Miller, M.S, Czabotar, P.E, Colman, P.M.
登録日2023-05-03
公開日2023-12-27
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids.
Febs J., 291, 2024
8SPE
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BU of 8spe by Molmil
Crystal structure of Bax core domain BH3-groove dimer - tetrameric fraction P31
分子名称: 1,2-ETHANEDIOL, Apoptosis regulator BAX, DI(HYDROXYETHYL)ETHER, ...
著者Miller, M.S, Cowan, A.D, Colman, P.M, Czabotar, P.E.
登録日2023-05-03
公開日2023-12-27
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids.
Febs J., 291, 2024
8SPD
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BU of 8spd by Molmil
Cytochrome P450 (CYP) 3A4 crystallized with clotrimazole
分子名称: 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE
著者Hsu, M.H, Johnson, E.F.
登録日2023-05-02
公開日2023-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Differential Effects of Clotrimazole on X-Ray Crystal Structures of Human Cytochromes P450 3A5 and 3A4.
Drug Metab.Dispos., 51, 2023
8SPC
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BU of 8spc by Molmil
Crystal structure of the cytochrome P450 enzyme RufO
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Cytochrome P450, ...
著者Dratch, B.D, Davis, K.M.
登録日2023-05-02
公開日2023-12-13
実験手法X-RAY DIFFRACTION (1.871 Å)
主引用文献Insights into Substrate Recognition by the Unusual Nitrating Enzyme RufO.
Acs Chem.Biol., 18, 2023
8SPB
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BU of 8spb by Molmil
Caspase-4/Pro-IL-18 complex
分子名称: Caspase-4 subunit p10, Caspase-4 subunit p20, Interleukin-18
著者Pascal, D, Dong, Y, Wu, H, Jon, K.
登録日2023-05-02
公開日2023-11-22
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into cytokine cleavage by inflammatory caspase-4.
Nature, 624, 2023
8SPA
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BU of 8spa by Molmil
Structural insights into cellular control of the human CPEB3 prion, functionally regulated by a labile-amyloid-forming segment
分子名称: Cytoplasmic polyadenylation element-binding protein 3
著者Flores, M.D, Sawaya, M.R, Boyer, D.R, Zink, S, Fioriti, L, Rodriguez, J.A.
登録日2023-05-02
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of a reversible amyloid fibril formed by the CPEB3 prion-like domain reveals a core sequence involved in translational regulation
To Be Published
8SP9
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BU of 8sp9 by Molmil
Crystal Structure of Coxsackievirus B3 (CVB3) Cloverleaf RNA with tRNA scaffold
分子名称: tRNA scaffold,CVB3 Cloverleaf RNA
著者Gottipati, K, McNeme, S.C, Choi, K.H.
登録日2023-05-02
公開日2023-08-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Structural basis for cloverleaf RNA-initiated viral genome replication.
Nucleic Acids Res., 51, 2023
8SP8
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BU of 8sp8 by Molmil
Human TRP channel TRPV6 in cNW30 nanodiscs inhibited by tetrahydrocannabivarin (THCV)
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHLORIDE ION, ...
著者Neuberger, A, Yelshanskaya, M.V, Nadezhdin, K.D, Sobolevsky, A.I.
登録日2023-05-02
公開日2023-08-23
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Molecular pathway and structural mechanism of human oncochannel TRPV6 inhibition by the phytocannabinoid tetrahydrocannabivarin.
Nat Commun, 14, 2023
8SP7
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BU of 8sp7 by Molmil
LINE-1 retrotransposon endonuclease domain complex with tranexamic acid
分子名称: LINE-1 retrotransposon endonuclease, SULFATE ION, TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID
著者D'Ordine, A.M, Jogl, G, Sedivy, J.M.
登録日2023-05-02
公開日2024-05-22
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Identification and characterization of small molecule inhibitors of the LINE-1 retrotransposon endonuclease.
Nat Commun, 15, 2024

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件を2024-06-26に公開中

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