8SPS

High resolution structure of ESRRB nucleosome bound OCT4 at site a and site b

Summary for 8SPS

• Entry DOI: 10.2210/pdb8sps/pdb
• EMDB information: 40683 40684 40686 40691
• Descriptor: DNA (168-MER), Maltodextrin-binding protein,POU domain, class 5, transcription factor 1, Histone H3.1, ... (8 entities in total)
• Functional Keywords: nucleosome, transcription factor, transcription, chromatin binding protein-dna complex, gene regulation, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 14
• Total formula weight: 393956.30

Authors

Lian, T.,Guan, R.,Bai, Y. (deposition date: 2023-05-03, release date: 2023-06-28)

• Primary citation: Guan, R.,Lian, T.,Zhou, B.R.,Wheeler, D.,Bai, Y.; Structural mechanism of LIN28B nucleosome targeting by OCT4.; Mol.Cell, 83:1970-1982.e6, 2023; PubMed: 37327775; DOI: 10.1016/j.molcel.2023.05.030

Experimental method

ELECTRON MICROSCOPY (3 Å)