PDB: 45677 件ウェブページステータス検索Chemie searchBIRD

---

4R74	Structure of the periplasmic binding protein AfuA from Actinobacillus pleuropneumoniae (exogenous fructose-6-phosphate bound) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-O-phosphono-beta-D-fructofuranose, ABC-type Fe3+ transport system, ... 著者 Sit, B, Calmettes, C, Moraes, T.F. 登録日 2014-08-26 公開日 2015-08-12 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen. Plos Pathog., 11, 2015
6F6F	R2-like ligand-binding oxidase V72I mutant with aerobically reconstituted Mn/Fe cofactor 分子名称: FE (III) ION, MANGANESE (II) ION, MANGANESE (III) ION, ... 著者 Griese, J.J, Hogbom, M. 登録日 2017-12-05 公開日 2018-07-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.788 Å) 主引用文献 Ether cross-link formation in the R2-like ligand-binding oxidase. J. Biol. Inorg. Chem., 23, 2018
6F5X	Crystal structure of the SYCP1 N-terminal head-to-head assembly in closed conformation 分子名称: IODIDE ION, Synaptonemal complex protein 1, TRIETHYLENE GLYCOL 著者 Ratcliff, M, Dunce, J.M, Davies, O.R. 登録日 2017-12-04 公開日 2018-06-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly. Nat. Struct. Mol. Biol., 25, 2018
4QVH	Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein 分子名称: CITRATE ANION, COENZYME A, GLYCEROL, ... 著者 Jung, J, Bashiri, G, Johnston, J.M, Baker, E.N. 登録日 2014-07-15 公開日 2014-12-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein. J.Struct.Biol., 188, 2014
6F65	R2-like ligand-binding oxidase A171F mutant with aerobically reconstituted Mn/Fe cofactor 分子名称: FE (III) ION, MANGANESE (II) ION, MANGANESE (III) ION, ... 著者 Griese, J.J, Hogbom, M. 登録日 2017-12-05 公開日 2018-12-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.948 Å) 主引用文献 Assembly of a heterodinuclear Mn/Fe cofactor is coupled to tyrosine-valine ether cross-link formation in the R2-like ligand-binding oxidase. J. Biol. Inorg. Chem., 24, 2019
8W68	Crystal structure of Q9PR55 at pH 6.0 (use NMR model) 分子名称: Uncharacterized protein UU089.1 著者 Hsu, M.F, Ko, T.P, Huang, K.F, Chen, Y.R, Huang, J.S, Hsu, S.T.D. 登録日 2023-08-28 公開日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure, dynamics, and stability of the smallest and most complex 7 1 protein knot. J.Biol.Chem., 300, 2023
6F7A	Gloeobacter Ligand-gated Ion Channel (GLIC) closed state crystallized in an ultra-swollen lipidic mesophase 分子名称: Proton-gated ion channel 著者 Martiel, I, Zabara, A, Chong, J.Y.T, Stark, L, Cromer, B, Dummond, C.J, Mezzenga, R. 登録日 2017-12-07 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (6 Å) 主引用文献 Design of ultra-swollen lipidic mesophases for the crystallization of membrane proteins with large extracellular domains. Nat Commun, 9, 2018
6PG1	Crystal Structure of EcDsbA in a complex with unpurified reaction product F1 (methylpiperazinone 6) 分子名称: 1,2-ETHANEDIOL, 2-methyl-4-{4-[2-(4-methyl-3-oxopiperazin-1-yl)-2-oxoethyl]phenoxy}benzonitrile, COPPER (II) ION, ... 著者 Ilyichova, O.V, Bentley, M, Doak, B, Scanlon, M.J. 登録日 2019-06-23 公開日 2020-07-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiL X ). J.Med.Chem., 63, 2020
5DRN	Context-independent anti-hypusine antibody FabHpu24 in complex with hypusine 分子名称: Fab Hpu24 Heavy chain, Fab Hpu24 Light chain, GLYCEROL, ... 著者 Zhai, Q, Carter, P.J. 登録日 2015-09-16 公開日 2016-01-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.994 Å) 主引用文献 Structural Analysis and Optimization of Context-Independent Anti-Hypusine Antibodies. J.Mol.Biol., 428, 2016
6PBM	Pseudopaline Dehydrogenase with NADP+ bound 分子名称: 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pseudopaline Dehydrogenase 著者 McFarlane, J.S, Lamb, A.L. 登録日 2019-06-14 公開日 2019-10-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Staphylopine and pseudopaline dehydrogenase from bacterial pathogens catalyze reversible reactions and produce stereospecific metallophores. J.Biol.Chem., 294, 2019
6FAX	Complex of Human CD40 Ectodomain with Lob 7.4 Fab 分子名称: Lob 7.4 heavy chain, Lob 7.4 light chain, Tumor necrosis factor receptor superfamily member 5 著者 Orr, C.M, Tews, I, Pearson, A.R. 登録日 2017-12-18 公開日 2018-02-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Complex Interplay between Epitope Specificity and Isotype Dictates the Biological Activity of Anti-human CD40 Antibodies. Cancer Cell, 33, 2018
5DTQ	Crystal structure of Dot1L in complex with inhibitor CPD3 [(2,6-dichlorophenyl)(quinolin-6-yl)methanone] 分子名称: (2,6-dichlorophenyl)(quinolin-6-yl)methanone, Histone-lysine N-methyltransferase, H3 lysine-79 specific 著者 Scheufler, C, Be, C, Moebitz, H, Stauffer, F. 登録日 2015-09-18 公開日 2016-06-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Optimization of a Fragment-Based Screening Hit toward Potent DOT1L Inhibitors Interacting in an Induced Binding Pocket. Acs Med.Chem.Lett., 7, 2016
6F2L	Crystal structure of the complex between PPARgamma LBD and the ligand LJ570: structure obtained from crystals of the apo-form soaked for 15 days. 分子名称: (2S)-3-(biphenyl-4-yl)-2-(biphenyl-4-yloxy)propanoic acid, Peroxisome proliferator-activated receptor gamma 著者 Pochetti, G, Montanari, M. 登録日 2017-11-24 公開日 2018-01-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Identification of the First PPAR alpha / gamma Dual Agonist Able To Bind to Canonical and Alternative Sites of PPAR gamma and To Inhibit Its Cdk5-Mediated Phosphorylation. J.Med.Chem., 61, 2018
8TFN	Structure of anti-TCRvbeta6-5 antibody in complex with the cognate TCR 分子名称: Anti-TCRVb6-5 Fab heavy chain, Anti-TCRVb6-5 Fab light chain, TRAV12-3, ... 著者 Katragadda, M, Servatalab, R, Wirth, J. 登録日 2023-07-11 公開日 2023-11-08 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Innate TCR beta-chain engagement drives human T cells toward distinct memory-like effector phenotypes with immunotherapeutic potentials. Sci Adv, 9, 2023
6LVT	Solution structure of holo acyl carrier protein from Thermotoga maritima 分子名称: Acyl carrier protein 著者 Lee, Y, Kim, Y. 登録日 2020-02-05 公開日 2020-12-09 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural Characterization of an ACP from Thermotoga maritima : Insights into Hyperthermal Adaptation. Int J Mol Sci, 21, 2020
6F3M	Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa complexed with adenosine, K+ and Zn2+ cations 分子名称: ADENOSINE, Adenosylhomocysteinase, GLYCEROL, ... 著者 Czyrko, J, Brzezinski, K. 登録日 2017-11-28 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Metal-cation regulation of enzyme dynamics is a key factor influencing the activity of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa. Sci Rep, 8, 2018
6PIS	Mouse two pore domain K+ channel TRAAK (K2P4.1) - Fab complex structure 分子名称: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, POTASSIUM ION, ... 著者 Brohawn, S.G. 登録日 2019-06-27 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier. Elife, 8, 2019
6PJ7	Time-resolved structural snapshot of proteolysis by GlpG inside the membrane 分子名称: Peptide aldehyde inhibitor, Rhomboid protease GlpG 著者 Urban, S, Cho, S. 登録日 2019-06-28 公開日 2019-10-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release. Nat.Struct.Mol.Biol., 26, 2019
8TG6	tRNA 2'-phosphotransferase (Tpt1) from Aeropyrum pernix in complex with sulfate anions 分子名称: CHLORIDE ION, Probable RNA 2'-phosphotransferase, SULFATE ION 著者 Jacewicz, A, Dantuluri, S, Shuman, S. 登録日 2023-07-12 公開日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD. Proc.Natl.Acad.Sci.USA, 120, 2023
6OYT	ASK1 kinase domain in complex with GS-4997 分子名称: 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}benzamide, ACETATE ION, Mitogen-activated protein kinase kinase kinase 5 著者 Marcotte, D.J. 登録日 2019-05-15 公開日 2019-11-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.824 Å) 主引用文献 Rational Design and Optimization of a Novel Class of Macrocyclic Apoptosis Signal-Regulating Kinase 1 Inhibitors. J.Med.Chem., 62, 2019
6PM9	Crystal structure of the core catalytic domain of human O-GlcNAcase bound to MK-8719 分子名称: (3aR,5S,6S,7R,7aR)-5-(difluoromethyl)-2-(ethylamino)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol, O-GlcNAcase TIM-barrel domain, O-GlcNAcase stalk domain 著者 Klein, D.J, Selnick, H.G, Duffy, J.L, McEachern, E.J. 登録日 2019-07-01 公開日 2019-09-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Discovery of MK-8719, a Potent O-GlcNAcase Inhibitor as a Potential Treatment for Tauopathies. J.Med.Chem., 62, 2019
7YZ9	Structure of catalytic domain of Rv1625c bound to nanobody NB4 分子名称: 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, Adenylate cyclase, GLYCEROL, ... 著者 Khanppnavar, B, Mehta, V.J, Iype, T, Korkhov, V.M. 登録日 2022-02-19 公開日 2022-08-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane adenylyl cyclases. Elife, 11, 2022
5E4O	Human transthyretin (TTR) complexed with (Z)-((3,4-Dichloro-phenyl)-methyleneaminooxy)-acetic acid 分子名称: ({(Z)-[(3,4-dichlorophenyl)(phenyl)methylidene]amino}oxy)acetic acid, Transthyretin 著者 Ciccone, L, Savko, M, Nencetti, S, Rossello, A, Orlandini, E, Stura, E.A. 登録日 2015-10-06 公開日 2016-03-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR). J Enzyme Inhib Med Chem, 31, 2016
6FA5	CRYSTAL STRUCTURE OF THE DEAH-BOX HELICASE PRP2 IN COMPLEX WITH ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Hamann, F, Schmitt, A, Neumann, P, Ficner, R. 登録日 2017-12-15 公開日 2018-07-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.303 Å) 主引用文献 Crystal structure of the spliceosomal DEAH-box ATPase Prp2. Acta Crystallogr D Struct Biol, 74, 2018
6P65	HIV Env 16055 NFL TD 2CC+ in complex with antibody 1C2 fragment antigen binding 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Ozorowski, G, Torres, J.L, Ward, A.B. 登録日 2019-05-31 公開日 2019-11-20 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.94 Å) 主引用文献 Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability. Immunity, 51, 2019

<1532153315341535153615371538153915401541154215431544154515461547>