6F3M

Crystal structure of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa complexed with adenosine, K+ and Zn2+ cations

Summary for 6F3M

• Entry DOI: 10.2210/pdb6f3m/pdb
• Descriptor: Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ADENOSINE, ... (9 entities in total)
• Functional Keywords: regulation of sam-dependent methylation reactions, hydrolase
• Biological source: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); More
• Total number of polymer chains: 4
• Total formula weight: 207320.94

Authors

Czyrko, J.,Brzezinski, K. (deposition date: 2017-11-28, release date: 2018-08-08, Last modification date: 2024-01-17)

• Primary citation: Czyrko, J.,Sliwiak, J.,Imiolczyk, B.,Gdaniec, Z.,Jaskolski, M.,Brzezinski, K.; Metal-cation regulation of enzyme dynamics is a key factor influencing the activity of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa.; Sci Rep, 8:11334-11334, 2018; PubMed: 30054521; DOI: 10.1038/s41598-018-29535-y

Experimental method

X-RAY DIFFRACTION (1.6 Å)