PDB: 221716 件ウェブページステータス検索Chemie searchBIRD

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8SRQ	Structure of human ULK1C:PI3KC3-C1 supercomplex 分子名称: Autophagy-related protein 13, Beclin 1-associated autophagy-related key regulator, Beclin-1-C 35 kDa, ... 著者 Chen, M, Hurley, J.H. 登録日 2023-05-05 公開日 2023-06-21 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex bioRxiv, 2023
8SRP	FoxP3 forms Ladder-like multimer to bridge TTTG repeats 分子名称: DNA 72-mer, Forkhead box protein P3 著者 Leng, F, Hur, S. 登録日 2023-05-05 公開日 2023-10-18 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 FOXP3 recognizes microsatellites and bridges DNA through multimerization. Nature, 624, 2023
8SRO	FoxP3 tetramer on TTTG repeats 分子名称: DNA 72-mer, Forkhead box protein P3 著者 Leng, F, Hur, S. 登録日 2023-05-05 公開日 2023-10-18 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 FOXP3 recognizes microsatellites and bridges DNA through multimerization. Nature, 624, 2023
8SRM	Structure of human ULK1 complex core (2:2:2 stoichiometry) of the ATG13(450-517) mutant 分子名称: Autophagy-related protein 13, RB1-inducible coiled-coil protein 1, Serine/threonine-protein kinase ULK1 著者 Chen, M, Hurley, J.H. 登録日 2023-05-05 公開日 2023-06-21 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (4.46 Å) 主引用文献 Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex bioRxiv
8SRL	Crystal structure of T151V CAO1 in complex with piceatannol 分子名称: BENZOIC ACID, Carotenoid oxygenase, FE (II) ION, ... 著者 Kiser, P.D. 登録日 2023-05-05 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystal structure of CAO1 To Be Published
8SRK	Cryo-EM structure of TRPM2 chanzyme (without NUDT9-H domain) in the presence of Ca and ADP-ribose 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, CHOLESTEROL, ... 著者 Huang, Y, Kumar, S, Lu, W, Du, J. 登録日 2023-05-05 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.14 Å) 主引用文献 Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
8SRJ	Cryo-EM structure of TRPM2 chanzyme (without NUDT9-H domain) in the presence of EDTA, apo state 分子名称: CHOLESTEROL, TRPM2 chanzyme 著者 Huang, Y, Kumar, S, Lu, W, Du, J. 登録日 2023-05-05 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.74 Å) 主引用文献 Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
8SRI	Cryo-EM structure of TRPM2 chanzyme (E1114A) in the presence of Magnesium and ADP-ribose, closed state 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ... 著者 Huang, Y, Kumar, S, Lu, W, Du, J. 登録日 2023-05-05 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (2.73 Å) 主引用文献 Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
8SRH	Cryo-EM structure of TRPM2 chanzyme (E1114A) in the presence of Magnesium and ADP-ribose, open state 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ... 著者 Huang, Y, Kumar, S, Lu, W, Du, J. 登録日 2023-05-05 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.79 Å) 主引用文献 Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
8SRG	Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, Adenosine monophosphate, and Ribose-5-phosphate 分子名称: 5-O-phosphono-beta-D-ribofuranose, ADENOSINE MONOPHOSPHATE, CHOLESTEROL, ... 著者 Huang, Y, Kumar, S, Lu, W, Du, J. 登録日 2023-05-05 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.03 Å) 主引用文献 Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
8SRF	Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, ADP-ribose, Adenosine monophosphate, and Ribose-5-phosphate, closed state 分子名称: 5-O-phosphono-beta-D-ribofuranose, ADENOSINE MONOPHOSPHATE, ADENOSINE-5-DIPHOSPHORIBOSE, ... 著者 Huang, Y, Kumar, S, Lu, W, Du, J. 登録日 2023-05-05 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (2.52 Å) 主引用文献 Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
8SRE	Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium and ADP-ribose, closed state 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ... 著者 Huang, Y, Kumar, S, Lu, W, Du, J. 登録日 2023-05-05 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (2.52 Å) 主引用文献 Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
8SRD	Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium and ADP-ribose, open state 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ... 著者 Huang, Y, Kumar, S, Lu, W, Du, J. 登録日 2023-05-05 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (2.91 Å) 主引用文献 Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
8SRC	Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium and ADP-ribose 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, CHOLESTEROL, ... 著者 Huang, Y, Kumar, S, Lu, W, Du, J. 登録日 2023-05-05 公開日 2024-05-08 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. Nat.Struct.Mol.Biol., 2024
8SRB	Cryo-EM structure of TRPM2 chanzyme in the presence of EDTA and ADP-ribose 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, TRPM2 chanzyme 著者 Huang, Y, Kumar, S, Lu, W, Du, J. 登録日 2023-05-05 公開日 2024-05-08 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.82 Å) 主引用文献 Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. Nat.Struct.Mol.Biol., 2024
8SRA	Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium 分子名称: CALCIUM ION, CHOLESTEROL, TRPM2 chanzyme 著者 Huang, Y, Kumar, S, Lu, W, Du, J. 登録日 2023-05-05 公開日 2024-05-08 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.93 Å) 主引用文献 Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. Nat.Struct.Mol.Biol., 2024
8SR9	Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium 分子名称: CHOLESTEROL, MAGNESIUM ION, TRPM2 chanzyme 著者 Huang, Y, Kumar, S, Lu, W, Du, J. 登録日 2023-05-05 公開日 2024-05-08 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.05 Å) 主引用文献 Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. Nat.Struct.Mol.Biol., 2024
8SR8	Cryo-EM structure of TRPM2 chanzyme in the presence of EDTA (apo state) 分子名称: CHOLESTEROL, TRPM2 chanzyme 著者 Huang, Y, Kumar, S, Lu, W, Du, J. 登録日 2023-05-05 公開日 2024-05-08 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.77 Å) 主引用文献 Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. Nat.Struct.Mol.Biol., 2024
8SR7	Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, Adenosine monophosphate, and Ribose-5-phosphate 分子名称: 5-O-phosphono-beta-D-ribofuranose, ADENOSINE MONOPHOSPHATE, CHOLESTEROL, ... 著者 Huang, Y, Kumar, S, Lu, W, Du, J. 登録日 2023-05-05 公開日 2024-05-08 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (1.97 Å) 主引用文献 Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. Nat.Struct.Mol.Biol., 2024
8SR6	Crystal structure of legAS4 from Legionella pneumophila subsp. pneumophila with histone H3 (3-17)peptide 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Eukaryotic huntingtin interacting protein B, ... 著者 Xu, C, Chung, I.Y.W, Cygler, M. 登録日 2023-05-05 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Histone methyltransferase activity of the secreted Legionella pneumophila SET-domain effector RomA/LegAS4 depends on its ankyrin domain To Be Published
8SR5	particulate methane monooxygenase potassium cyanide treated 分子名称: Ammonia monooxygenase/methane monooxygenase, subunit C family protein, COPPER (II) ION, ... 著者 Tucci, F.J, Rosenzweig, A.C. 登録日 2023-05-05 公開日 2023-11-29 最終更新日 2024-01-24 実験手法 ELECTRON MICROSCOPY (3.22 Å) 主引用文献 Product analog binding identifies the copper active site of particulate methane monooxygenase. Nat Catal, 6, 2023
8SR4	particulate methane monooxygeanse treated with potassium cyanide and copper reloaded 分子名称: Ammonia monooxygenase/methane monooxygenase, subunit C family protein, COPPER (II) ION, ... 著者 Tucci, F.J, Jodts, R.J, Rosenzweig, A.C. 登録日 2023-05-05 公開日 2023-11-15 最終更新日 2024-01-24 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Product analog binding identifies the copper active site of particulate methane monooxygenase. Nat Catal, 6, 2023
8SR2	particulate methane monooxygenase incubated with 4,4,4-trifluorobutanol 分子名称: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Ammonia monooxygenase/methane monooxygenase, ... 著者 Tucci, F.J, Rosenzweig, A.C. 登録日 2023-05-05 公開日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.36 Å) 主引用文献 Product analogue binding identifies the copper active site of particulate methane monooyxgenase Nat Catal, 2023
8SR1	particulate methane monooxygenase crosslinked with 4,4,4-trifluorobutanol bound 分子名称: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dihexanoyl-sn-glycero-3-phosphocholine, 4,4,4-trifluorobutan-1-ol, ... 著者 Tucci, F.J, Rosenzweig, A.C. 登録日 2023-05-05 公開日 2023-11-15 最終更新日 2024-01-24 実験手法 ELECTRON MICROSCOPY (2.18 Å) 主引用文献 Product analog binding identifies the copper active site of particulate methane monooxygenase. Nat Catal, 6, 2023
8SR0	CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 local refined 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, favezelimab Fab heavy chain, ... 著者 Mishra, A.K, Shahid, S, Karade, S.S, Mariuzza, R.A. 登録日 2023-05-05 公開日 2023-09-06 最終更新日 2023-10-18 実験手法 ELECTRON MICROSCOPY (3.53 Å) 主引用文献 CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker. Structure, 31, 2023

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