8SRF

Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, ADP-ribose, Adenosine monophosphate, and Ribose-5-phosphate, closed state

Summary for 8SRF

• Entry DOI: 10.2210/pdb8srf/pdb
• EMDB information: 40729 40870 40881
• Descriptor: TRPM2 chanzyme, 5-O-phosphono-beta-D-ribofuranose, ADENOSINE MONOPHOSPHATE, ... (7 entities in total)
• Functional Keywords: trpm2 chanzyme, channel-enzyme, membrane protein
• Biological source: Salpingoeca rosetta
• Total number of polymer chains: 4
• Total formula weight: 682706.78

Authors

Huang, Y.,Kumar, S.,Lu, W.,Du, J. (deposition date: 2023-05-05, release date: 2024-05-15)

• Primary citation: Huang, Y.,Lu, W.,Du, J.; Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.52 Å)