8SRF
Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, ADP-ribose, Adenosine monophosphate, and Ribose-5-phosphate, closed state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | TRPM2 chanzyme | polymer | 1494 | 168252.5 | 4 | UniProt (F2UB89) Pfam (PF18139) Pfam (PF00520) | Salpingoeca rosetta | Nudt9 protein |
| 2 | BA, E, OA, Q (C, A, D, B) | 5-O-phosphono-beta-D-ribofuranose | non-polymer | 230.1 | 4 | Chemie (RP5) | |||
| 3 | CA, F, PA, R (C, A, D, B) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 4 | Chemie (AMP) | |||
| 4 | DA, G, QA, S (C, A, D, B) | ADENOSINE-5-DIPHOSPHORIBOSE | non-polymer | 559.3 | 4 | Chemie (APR) | |||
| 5 | EA, FA, GA, H, HA... (C, A, D, B) | MAGNESIUM ION | non-polymer | 24.3 | 21 | Chemie (MG) | |||
| 6 | AA, JA, KA, LA, M... (B, C, A, D) | CHOLESTEROL | non-polymer | 386.7 | 12 | Chemie (CLR) | |||
| 7 | AB, XA, YA, ZA (D, A, B, C) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 673009.9 | |
| Non-Polymers* | Number of molecules | 45 |
| Total formula weight | 9696.8 | |
| All* | Total formula weight | 682706.8 |
