8SRI

Cryo-EM structure of TRPM2 chanzyme (E1114A) in the presence of Magnesium and ADP-ribose, closed state

Summary for 8SRI

• Entry DOI: 10.2210/pdb8sri/pdb
• EMDB information: 40732 40872 40888
• Descriptor: TRPM2 chanzyme, ADENOSINE-5-DIPHOSPHORIBOSE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: trpm2 chanzyme, channel-enzyme, membrane protein
• Biological source: Salpingoeca rosetta
• Total number of polymer chains: 4
• Total formula weight: 682281.07

Authors

Huang, Y.,Kumar, S.,Lu, W.,Du, J. (deposition date: 2023-05-05, release date: 2024-05-15)

• Primary citation: Huang, Y.,Lu, W.,Du, J.; Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.73 Å)