8SRQ

Structure of human ULK1C:PI3KC3-C1 supercomplex

Summary for 8SRQ

• Entry DOI: 10.2210/pdb8srq/pdb
• Related: 8SOI 8SOR 8SQZ 8SRM
• EMDB information: 40738
• Descriptor: RB1-inducible coiled-coil protein 1, Serine/threonine-protein kinase ULK1, Autophagy-related protein 13, ... (7 entities in total)
• Functional Keywords: autophagy, protein kinase, lipid kinase, supercomplex, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 423297.40

Authors

Chen, M.,Hurley, J.H. (deposition date: 2023-05-05, release date: 2023-06-21)

• Primary citation: Chen, M.,Ren, X.,Cook, A.,Hurley, J.H.; Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex; bioRxiv, 2023; DOI: 10.1101/2023.06.01.543278

Experimental method

ELECTRON MICROSCOPY (6.2 Å)