8SRP

FoxP3 forms Ladder-like multimer to bridge TTTG repeats

Summary for 8SRP

• Entry DOI: 10.2210/pdb8srp/pdb
• EMDB information: 40737
• Descriptor: Forkhead box protein P3, DNA 72-mer (3 entities in total)
• Functional Keywords: foxp3, strs, transcriptional factor, fkh, transcription, transcription-dna complex, transcription/dna
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 14
• Total formula weight: 361583.72

Authors

Leng, F.,Hur, S. (deposition date: 2023-05-05, release date: 2023-10-18, Last modification date: 2023-12-27)

• Primary citation: Zhang, W.,Leng, F.,Wang, X.,Ramirez, R.N.,Park, J.,Benoist, C.,Hur, S.; FOXP3 recognizes microsatellites and bridges DNA through multimerization.; Nature, 624:433-441, 2023; PubMed: 38030726; DOI: 10.1038/s41586-023-06793-z

Experimental method

ELECTRON MICROSCOPY (3.7 Å)