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2G5B
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Crystal Structure of the anti-Bax monoclonal antibody 6A7 and a Bax peptide.
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6A7 Fab Heavy Chain, 6A7 Fab Light Chain, ...
著者Peyerl, F.W, Dai, S, Murphy, G.A, Marrack, P, Kappler, J.W.
登録日2006-02-22
公開日2006-07-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Elucidation of some Bax conformational changes through crystallization of an antibody-peptide complex.
Cell Death Differ., 14, 2007
2G5C
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Crystal Structure of Prephenate Dehydrogenase from Aquifex aeolicus
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, prephenate dehydrogenase
著者Sun, W, Singh, S, Zhang, R, Turnbull, J.L, Christendat, D.
登録日2006-02-22
公開日2006-03-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Prephenate Dehydrogenase from Aquifex aeolicus: Insights into the Catalytic Mechanism
J.Biol.Chem., 281, 2006
2G5D
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Crystal structure of MltA from Neisseria gonorrhoeae Monoclinic form
分子名称: GNA33
著者Davies, C.
登録日2006-02-22
公開日2006-03-21
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structures of the Lytic Transglycosylase MltA from N.gonorrhoeae and E.coli: Insights into Interdomain Movements and Substrate Binding.
J.Mol.Biol., 359, 2006
2G5F
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The structure of MbtI from Mycobacterium Tuberculosis, the first enzyme in the synthesis of Mycobactin, reveals it to be a salicylate synthase
分子名称: COG0147: Anthranilate/para-aminobenzoate synthases component I, GLYCEROL, IMIDAZOLE, ...
著者Harrison, A.J, Lott, J.S, Yu, M, Ramsay, R, Baker, E.N, TB Structural Genomics Consortium (TBSGC)
登録日2006-02-22
公開日2006-09-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Structure of MbtI from Mycobacterium tuberculosis, the First Enzyme in the Biosynthesis of the Siderophore Mycobactin, Reveals It To Be a Salicylate Synthase
J.Bacteriol., 188, 2006
2G5G
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Cofacial heme binding to ChaN of Campylobacter jejuni
分子名称: PROTOPORPHYRIN IX CONTAINING FE, putative lipoprotein
著者Chan, A.C, Murphy, M.E.
登録日2006-02-22
公開日2006-10-03
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cofacial Heme Binding is Linked to Dimerization by a Bacterial Heme Transport Protein.
J.Mol.Biol., 362, 2006
2G5H
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Structure of tRNA-Dependent Amidotransferase GatCAB
分子名称: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Glutamyl-tRNA(Gln) amidotransferase subunit A, ...
著者Nakamura, A, Yao, M, Tanaka, I.
登録日2006-02-23
公開日2006-07-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ammonia channel couples glutaminase with transamidase reactions in GatCAB
Science, 312, 2006
2G5I
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Structure of tRNA-Dependent Amidotransferase GatCAB complexed with ADP-AlF4
分子名称: ADENOSINE-5'-DIPHOSPHATE, Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, ...
著者Nakamura, A, Yao, M, Tanaka, I.
登録日2006-02-23
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Ammonia channel couples glutaminase with transamidase reactions in GatCAB
Science, 312, 2006
2G5K
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Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site complexed with Apramycin
分子名称: 5'-R(*UP*UP*GP*CP*GP*UP*CP*GP*CP*UP*CP*CP*GP*GP*AP*AP*AP*AP*GP*UP*CP*GP*C)-3', APRAMYCIN, COBALT HEXAMMINE(III), ...
著者Kondo, J, Francois, B, Urzhumtsev, A, Westhof, E.
登録日2006-02-23
公開日2006-06-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site Complexed with Apramycin
Angew.Chem.Int.Ed.Engl., 45, 2006
2G5L
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Streptavidin in complex with Nanotag
分子名称: (FME)(ASP)(VAL)(GLU)(ALA)(TRP)(LEU), GLYCEROL, SULFATE ION, ...
著者Perbandt, M, Bruns, O, Vallazza, M, Lamla, T, Betzel, C, Erdmann, V.A.
登録日2006-02-23
公開日2007-02-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献High resolution structure of Streptavidin in complex with a novel high affinity peptide tag mimicking the biotin binding motif
To be Published
2G5M
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Spinophilin PDZ domain
分子名称: Neurabin-2
著者Kelker, M.S, Peti, W.
登録日2006-02-23
公開日2007-01-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural basis for spinophilin-neurabin receptor interaction.
Biochemistry, 46, 2007
2G5N
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Indole-amidine Complexes with Bovine Trypsin
分子名称: 2-(3-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE, CALCIUM ION, Cationic trypsin, ...
著者Kline, A.D, Briggs, S.L, Subramaniam, S.
登録日2006-02-23
公開日2006-08-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Ligand Epitoping By Proton NMR Chemical Shift Differences
To be published
2G5O
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Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide
分子名称: (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL, Estrogen receptor, Nuclear receptor coactivator 2
著者Rajan, S.S, Hsieh, R.W, Sharma, S.K, Greene, G.L.
登録日2006-02-23
公開日2007-03-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide
To be Published
2G5P
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BU of 2g5p by Molmil
Crystal structure of human dipeptidyl peptidase IV (DPPIV) complexed with cyanopyrrolidine (C5-pro-pro) inhibitor 21ac
分子名称: 4-{[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHOXY}-3-TERT-BUTYLBENZOIC ACID, Dipeptidyl peptidase 4
著者Longenecker, K.L, Fry, E.H, Lake, M.R, Solomon, L.R, Pei, Z, Li, X.
登録日2006-02-23
公開日2006-07-04
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors.
J.Med.Chem., 49, 2006
2G5R
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BU of 2g5r by Molmil
Crystal structure of Siglec-7 in complex with methyl-9-(aminooxalyl-amino)-9-deoxyNeu5Ac (oxamido-Neu5Ac)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, Sialic acid-binding Ig-like lectin 7, ...
著者Attrill, H, Crocker, P.R, van Aalten, D.M.
登録日2006-02-23
公開日2006-06-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design.
Biochem.J., 397, 2006
2G5T
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Crystal structure of human dipeptidyl peptidase IV (DPPIV) complexed with cyanopyrrolidine (C5-pro-pro) inhibitor 21ag
分子名称: 3-{[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHOXY}-4-CHLOROBENZOIC ACID, Dipeptidyl peptidase 4
著者Longenecker, K.L, Fry, E.H, Lake, M.R, Solomon, L.R, Pei, Z, Li, X.
登録日2006-02-23
公開日2006-07-04
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors.
J.Med.Chem., 49, 2006
2G5U
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BU of 2g5u by Molmil
Human Transthyretin (TTR) Complexed with Hydroxylated polychlorinated Biphenyl-4,4'-dihydroxy-3,3',5,5'-tetrachlorobiphenyl
分子名称: 3,5,3',5'-TETRACHLORO-BIPHENYL-4,4'-DIOL, Transthyretin
著者Palaninathan, S.K, Smith, C, Safe, S.H, Kelly, J.W, Sacchettini, J.C.
登録日2006-02-23
公開日2006-03-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Hydroxylated polychlorinated biphenyls selectively bind transthyretin in blood and inhibit amyloidogenesis: rationalizing rodent PCB toxicity
Chem.Biol., 11, 2004
2G5V
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Indole-amidine Complexes with Bovine Trypsin
分子名称: 2-(2-METHYLPHENYL)-1H-INDOLE-6-CARBOXIMIDAMIDE, CALCIUM ION, Cationic trypsin
著者Kline, A.D, Briggs, S.L, Subramaniam, S.
登録日2006-02-23
公開日2006-08-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Ligand Epitoping By Proton NMR Chemical Shift Differences
To be published
2G5W
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X-ray crystal structure of Arabidopsis thaliana 12-oxophytodienoate reductase isoform 3 (AtOPR3) in complex with 8-iso prostaglandin A1 and its cofactor, flavin mononucleotide.
分子名称: (8S,12S)-15S-HYDROXY-9-OXOPROSTA-10Z,13E-DIEN-1-OIC ACID, 12-oxophytodienoate reductase 3, FLAVIN MONONUCLEOTIDE
著者Han, B.W, Malone, T.E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Fox, B.G, Center for Eukaryotic Structural Genomics (CESG)
登録日2006-02-23
公開日2006-04-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.576 Å)
主引用文献Crystal structure of Arabidopsis thaliana 12-oxophytodienoate reductase isoform 3 in complex with 8-iso prostaglandin A(1).
Proteins, 79, 2011
2G5X
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Crystal structure of lychnin a type 1 Ribosome Inactivating Protein (RIP)
分子名称: Ribosome-inactivating protein
著者Fermani, S, Falini, G, Tosi, G, Ripamonti, A, Polito, L, Bolognesi, A, Stirpe, F.
登録日2006-02-23
公開日2007-03-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of lychnin a type 1 Ribosome Inactivating Protein (RIP)
To be Published
2G5Z
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Structure of S65G Y66S GFP variant after spontaneous peptide hydrolysis and decarboxylation
分子名称: Green fluorescent protein, MAGNESIUM ION
著者Barondeau, D.P, Kassmann, C.J, Tainer, J.A, Getzoff, E.D.
登録日2006-02-23
公開日2006-04-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Understanding GFP Posttranslational Chemistry: Structures of Designed Variants that Achieve Backbone Fragmentation, Hydrolysis, and Decarboxylation.
J.Am.Chem.Soc., 128, 2006
2G60
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Structure of anti-FLAG M2 Fab domain
分子名称: anti-FLAG M2 Fab heavy chain, anti-FLAG M2 Fab light chain
著者Roosild, T.P.
登録日2006-02-23
公開日2006-09-12
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of anti-FLAG M2 Fab domain and its use in the stabilization of engineered membrane proteins.
Acta Crystallogr.,Sect.F, 62, 2006
2G62
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Crystal structure of human PTPA
分子名称: GLYCEROL, SULFATE ION, protein phosphatase 2A, ...
著者Magnusdottir, A, Stenmark, P, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Hogbom, M, Holmberg Schiavone, L, Kotenyova, T, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Nordlund, P.
登録日2006-02-24
公開日2006-04-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structure of a human PP2A phosphatase activator reveals a novel fold and highly conserved cleft implicated in protein-protein interactions.
J.Biol.Chem., 281, 2006
2G63
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Crystal structure of human dipeptidyl peptidase IV (DPPIV) complexed with cyanopyrrolidine (C5-pro-pro) inhibitor 24b
分子名称: Dipeptidyl peptidase 4, METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATE
著者Longenecker, K.L, Fry, E.H, Lake, M.R, Solomon, L.R, Pei, Z, Li, X.
登録日2006-02-24
公開日2006-07-04
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors.
J.Med.Chem., 49, 2006
2G64
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Structure of Caenorhabditis elegans 6-pyruvoyl tetrahydropterin synthase
分子名称: GLYCEROL, Putative 6-pyruvoyl tetrahydrobiopterin synthase, SODIUM ION, ...
著者Wengerter, B.C, Patskovsky, Y, Zhan, C, Ramagopal, U, Milstein, S, Vidal, M, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-02-24
公開日2006-03-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Caenorhabditis Elegans 6-Pyruvoyl Tetrahydropterin Synthase
To be Published
2G66
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Crystal structure of a collagen-like peptide with 3(S)Hyp in the Xaa position
分子名称: collagen
著者Schumacher, M.A, Mizuno, K, Bachinger, H.P.
登録日2006-02-24
公開日2006-08-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structure of a Collagen-like Polypeptide with 3(S)-Hydroxyproline Residues in the Xaa Position Forms a Standard 7/2 Collagen Triple Helix
J.Biol.Chem., 281, 2006

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