2G5O

Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide

Summary for 2G5O

• Entry DOI: 10.2210/pdb2g5o/pdb
• Related: 2G44
• Descriptor: Estrogen receptor, Nuclear receptor coactivator 2, (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL, ... (4 entities in total)
• Functional Keywords: estrogen receptor, lbd, grip peptide, hormone-growth factor receptor complex, hormone/growth factor receptor
• Biological source: Homo sapiens (human); More
• Cellular location: Isoform 1: Nucleus. Isoform 3: Nucleus: P03372; Nucleus: Q15596
• Total number of polymer chains: 4
• Total formula weight: 62868.45

Authors

Rajan, S.S.,Hsieh, R.W.,Sharma, S.K.,Greene, G.L. (deposition date: 2006-02-23, release date: 2007-03-06, Last modification date: 2023-08-30)

• Primary citation: Hsieh, R.W.,Greene, G.L.; Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide; To be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)