PDB: 1358 件ウェブページステータス検索Chemie searchBIRD

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8EV6	Crystal structure of the Thermus thermophilus 70S ribosome in complex with amikacin, mRNA, and A-, P-, and E-site tRNAs 分子名称: (2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S ,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Seely, S.M, Gagnon, M.G. 登録日 2022-10-19 公開日 2023-08-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.946 Å) 主引用文献 Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome. Nat Commun, 14, 2023
8CVO	Cutibacterium acnes 30S ribosomal subunit with Sarecycline bound, head domain only in the local refined map 分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S13, ... 著者 Lomakin, I.B, Devarkar, S.C, Bunick, C.G. 登録日 2022-05-18 公開日 2023-03-15 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism. Nucleic Acids Res., 51, 2023
4U1U	Crystal structure of the E. coli ribosome bound to quinupristin. 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. 登録日 2014-07-16 公開日 2014-07-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Synergy of streptogramin antibiotics occurs independently of their effects on translation. Antimicrob.Agents Chemother., 58, 2014
4WSD	Complex of 70S ribosome with tRNA-Phe and mRNA with C-A mismatch in the second position in the A-site and with antibiotic paromomycin. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. 登録日 2014-10-27 公開日 2015-06-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
6SKF	Cryo-EM Structure of T. kodakarensis 70S ribosome 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Matzov, D, Sas-Chen, A, Thomas, J.M, Santangelo, T, Meier, J.L, Schwartz, S, Shalev-Benami, M. 登録日 2019-08-15 公開日 2020-07-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping. Nature, 583, 2020
6SPC	Pseudomonas aeruginosa 30s ribosome from an aminoglycoside resistant clinical isolate 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Halfon, Y, Jimenez-Fernande, A, La Ros, R, Espinos, R, Krogh Johansen, H, Matzov, D, Eyal, Z, Bashan, A, Zimmerman, E, Belousoff, M, Molin, S, Yonath, A. 登録日 2019-09-01 公開日 2019-10-16 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate. Proc.Natl.Acad.Sci.USA, 116, 2019
5NDK	Crystal structure of aminoglycoside TC007 co-crystallized with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. 登録日 2017-03-08 公開日 2017-12-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7AFA	Bacterial 30S ribosomal subunit assembly complex state F (head domain) 分子名称: 16SrRNA (head domain of the 30S ribosome), 30S ribosomal protein S10, 30S ribosomal protein S13, ... 著者 Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Kaminishi, T, Diercks, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. 登録日 2020-09-19 公開日 2021-07-07 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
4V90	Thermus thermophilus Ribosome 分子名称: 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Chen, Y, Feng, S, Kumar, V, Ero, R, Gao, Y.G. 登録日 2014-02-22 公開日 2014-07-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structure of EF-G-ribosome complex in a pretranslocation state. Nat. Struct. Mol. Biol., 20, 2013
5E81	Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with wobble pair 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G. 登録日 2015-10-13 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code. Nat Commun, 7, 2016
6UO1	Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA (containing pseudouridine at the first position of the codon) and deacylated A-, P-, and E-site tRNAs at 2.95A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Batool, Z, Dobosz-Bartoszek, M, Polikanov, Y.S. 登録日 2019-10-14 公開日 2019-11-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Pseudouridinylation of mRNA coding sequences alters translation. Proc.Natl.Acad.Sci.USA, 116, 2019
5J91	Structure of the Wild-type 70S E coli ribosome bound to Tigecycline 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... 著者 Cocozaki, A, Ferguson, A. 登録日 2016-04-08 公開日 2016-07-06 最終更新日 2016-08-03 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. Proc.Natl.Acad.Sci.USA, 113, 2016
7AF5	Bacterial 30S ribosomal subunit assembly complex state I (head domain) 分子名称: 16SrRNA (head domain of the 30S ribosome), 30S ribosomal protein S10, 30S ribosomal protein S13, ... 著者 Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. 登録日 2020-09-19 公開日 2021-07-07 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
6HRM	E. coli 70S d2d8 stapled ribosome 分子名称: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... 著者 Schmied, W.H, Tnimov, Z, Uttamapinant, C, Rae, C.D, Fried, S.D, Chin, J.W. 登録日 2018-09-27 公開日 2018-12-19 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 Controlling orthogonal ribosome subunit interactions enables evolution of new function. Nature, 564, 2018
5IBB	Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and cognate tRNAVal in the A-site 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. 登録日 2016-02-22 公開日 2016-05-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix. Nucleic Acids Res., 44, 2016
7NAX	Complete Bacterial 30S ribosomal subunit assembly complex state I (Consensus Refinement) 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. 登録日 2021-01-25 公開日 2021-12-08 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
6GSJ	Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and cognate tRNAThr in the A-site 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Yusupov, M, Yusupova, G. 登録日 2018-06-14 公開日 2018-07-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria. Nucleic Acids Res., 46, 2018
5MDV	Structure of ArfA and RF2 bound to the 70S ribosome (accommodated state) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V. 登録日 2016-11-13 公開日 2016-12-14 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Translational termination without a stop codon. Science, 354, 2016
7MSC	Mtb 70SIC in complex with MtbEttA at Pre_R0 state 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Cui, Z, Zhang, J. 登録日 2021-05-11 公開日 2022-02-02 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
8RXX	CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : LM32Cs3H1 sKO STRAIN 分子名称: 40S ribosomal protein S12, 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, ... 著者 Rajan, K.S, Yonath, A. 登録日 2024-02-08 公開日 2024-05-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
8PPK	Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N. 登録日 2023-07-07 公開日 2023-10-18 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 Universal features of Nsp1-mediated translational shutdown by coronaviruses. Mol.Cell, 83, 2023
5IB7	Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet, near-cognate tRNALys with U-G mismatch in the A-site and antibiotic paromomycin 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. 登録日 2016-02-22 公開日 2016-05-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix. Nucleic Acids Res., 44, 2016
4V88	The structure of the eukaryotic ribosome at 3.0 A resolution. 分子名称: 18S RIBOSOMAL RNA, 18S rRNA, 25S rRNA, ... 著者 Ben-Shem, A, Garreau de Loubresse, N, Melnikov, S, Jenner, L, Yusupova, G, Yusupov, M. 登録日 2011-10-11 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of the eukaryotic ribosome at 3.0 angstrom resolution. Science, 334, 2011
4V9R	Crystal structure of antibiotic DITYROMYCIN bound to 70S ribosome 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... 著者 Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A. 登録日 2013-12-05 公開日 2014-07-09 最終更新日 2014-12-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation. Cell Rep, 6, 2014
4V67	Crystal structure of a translation termination complex formed with release factor RF2. 分子名称: 16S RRNA, 23S RRNA, 30S ribosomal protein S10, ... 著者 Korostelev, A, Asahara, H, Lancaster, L, Laurberg, M, Hirschi, A, Noller, H.F. 登録日 2008-10-27 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of a translation termination complex formed with release factor RF2. Proc.Natl.Acad.Sci.USA, 105, 2008

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