PDB: 10938 件ウェブページステータス検索Chemie searchBIRD

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2V88	Crystal structure of RAG2-PHD finger in complex with H3R2me2sK4me2 peptide 分子名称: H3R2ME2SK4ME3 PEPTIDE, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION 著者 Ramon-Maiques, S, Yang, W. 登録日 2007-08-03 公開日 2007-12-11 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2. Proc.Natl.Acad.Sci.USA, 104, 2007
2V86	Crystal structure of RAG2-PHD finger in complex with H3R2me2aK4me3 peptide 分子名称: H3R2ME2AK4ME3 PEPTIDE, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION 著者 Ramon-Maiques, S, Yang, W. 登録日 2007-08-02 公開日 2007-12-11 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2. Proc.Natl.Acad.Sci.USA, 104, 2007
2XB1	Crystal structure of the human Pygo2 PHD finger in complex with the B9L HD1 domain 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, PYGOPUS HOMOLOG 2, ... 著者 Miller, T.C, Rutherford, T.J, Johnson, C.M, Fiedler, M, Bienz, M. 登録日 2010-04-01 公開日 2010-07-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Allosteric Remodeling of the Histone H3 Binding Pocket in the Pygo2 Phd Finger Triggered by its Binding to the B9L/Bcl9 Co-Factor. J.Mol.Biol., 401, 2010
2DEW	Crystal structure of human peptidylarginine deiminase 4 in complex with histone H3 N-terminal tail including Arg8 分子名称: 10-mer peptide from histone H3, CALCIUM ION, Protein-arginine deiminase type IV, ... 著者 Arita, K, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M. 登録日 2006-02-18 公開日 2006-04-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4 Proc.Natl.Acad.Sci.Usa, 103, 2006
2DEX	Crystal structure of human peptidylarginine deiminase 4 in complex with histone H3 N-terminal peptide including Arg17 分子名称: 10-mer peptide from histone H3, CALCIUM ION, Protein-arginine deiminase type IV, ... 著者 Arita, K, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M. 登録日 2006-02-18 公開日 2006-04-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4 Proc.Natl.Acad.Sci.Usa, 103, 2006
3GL6	Crystal structure of JARID1A-PHD3 complexed with H3(1-9)K4me3 peptide 分子名称: Histone H3, Histone demethylase JARID1A, ZINC ION 著者 Wang, Z, Song, J, Patel, D.J. 登録日 2009-03-11 公開日 2009-05-05 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature, 459, 2009
3IV2	Crystal structure of mature apo-Cathepsin L C25A mutant 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cathepsin L1, GLYCEROL, ... 著者 Adams-Cioaba, M.A, Krupa, J.C, Mort, J.S, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J. 登録日 2009-08-31 公開日 2010-03-23 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for the recognition and cleavage of histone H3 by cathepsin L. Nat Commun, 2, 2011
5IX2	Crystal structure of mouse Morc3 ATPase-CW cassette in complex with AMPPNP and unmodified H3 peptide 分子名称: MAGNESIUM ION, MORC family CW-type zinc finger protein 3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Li, S, Du, J, Patel, D.J. 登録日 2016-03-23 公開日 2016-08-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin Proc.Natl.Acad.Sci.USA, 113, 2016
3AVS	Catalytic fragment of UTX/KDM6A bound with N-oxyalylglycine, and Ni(II) 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Lysine-specific demethylase 6A, ... 著者 Sengoku, T, Yokoyama, S. 登録日 2011-03-07 公開日 2011-10-19 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A Genes Dev., 25, 2011
4LJN	Crystal Structure of MOZ double PHD finger 分子名称: Histone acetyltransferase KAT6A, ZINC ION 著者 Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. 登録日 2013-07-05 公開日 2013-10-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification. Nucleic Acids Res., 42, 2014
2L5A	Structural basis for recognition of centromere specific histone H3 variant by nonhistone Scm3 分子名称: Histone H3-like centromeric protein CSE4, Protein SCM3, Histone H4 著者 Zhou, Z, Feng, H, Zhou, B, Ghirlando, R, Hu, K, Zwolak, A, Jenkins, L, Xiao, H, Tjandra, N, Wu, C, Bai, Y. 登録日 2010-10-28 公開日 2011-03-16 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3. Nature, 472, 2011
2L3R	NMR structure of UHRF1 Tandem Tudor Domains in a complex with Histone H3 peptide 分子名称: E3 ubiquitin-protein ligase UHRF1, Histone H3 著者 Nady, N, Lemak, A, Fares, C, Gutmanas, A, Avvakumov, G, Xue, S, Arrowsmith, C, Structural Genomics Consortium (SGC) 登録日 2010-09-21 公開日 2011-04-13 最終更新日 2020-02-05 実験手法 SOLUTION NMR 主引用文献 Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein. J.Biol.Chem., 286, 2011
2RVM	Solution structure of the chromodomain of HP1alpha with the phosphorylated N-terminal tail 分子名称: Chromobox protein homolog 5 著者 Kawaguchi, A, Nishimura, Y. 登録日 2015-12-18 公開日 2016-03-16 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail Sci Rep, 6, 2016
4GUS	Crystal structure of LSD2-NPAC with H3 in space group P3221 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Histone H3.3, ... 著者 Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y. 登録日 2012-08-29 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation Mol.Cell, 49, 2013
4GUR	Crystal structure of LSD2-NPAC with H3 in space group P21 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Histone H3.3, ... 著者 Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y. 登録日 2012-08-29 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.506 Å) 主引用文献 LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation Mol.Cell, 49, 2013
7EIF	Crystal structure of GAS41 YEATS domain 分子名称: GLYCEROL, YEATS domain-containing protein 4 著者 Kikuchi, M, Umehara, T. 登録日 2021-03-30 公開日 2022-04-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain. Proc.Natl.Acad.Sci.USA, 120, 2023
5DX0	Crystal structure of CARM1, sinefungin, and H3 peptide (R17) 分子名称: GLYCEROL, H3 peptide, Histone-arginine methyltransferase CARM1, ... 著者 Boriack-Sjodin, P.A. 登録日 2015-09-23 公開日 2015-11-25 最終更新日 2016-03-30 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural Insights into Ternary Complex Formation of Human CARM1 with Various Substrates. Acs Chem.Biol., 11, 2016
2RVL	Solution structure of the chromodomain of HP1alpha with the N-terminal tail 分子名称: Chromobox protein homolog 5 著者 Kawaguchi, A, Nishimura, Y. 登録日 2015-12-18 公開日 2016-03-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail Sci Rep, 6, 2016
3DB3	Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 in complex with trimethylated histone H3-K9 peptide 分子名称: E3 ubiquitin-protein ligase UHRF1, Trimethylated histone H3-K9 peptide 著者 Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2008-05-30 公開日 2008-09-16 最終更新日 2012-04-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein. J.Biol.Chem., 286, 2011
4OUC	Structure of human haspin in complex with histone H3 substrate 分子名称: (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, 1,2-ETHANEDIOL, Histone H3.2, ... 著者 Chaikuad, A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2014-02-15 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Modulation of the chromatin phosphoproteome by the haspin protein kinase. Mol Cell Proteomics, 13, 2014
5Y2L	Crystal structure of a group 2 HA binding antibody AF4H1K1 Fab in complex with the 1968 H3N2 pandemic (H3-AC/68) hemagglutinin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... 著者 Xiao, H, Qi, J, Gao, F.G. 登録日 2017-07-26 公開日 2019-01-30 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.902 Å) 主引用文献 An H3-clade neutralizing antibody screened from an H7N9 patient that binds group 2 influenza A hemagglutinins To Be Published
5H6Q	Crystal structure of LSD1-CoREST in complex with peptide 11 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ... 著者 Kikuchi, M, Amano, Y, Sato, S, Yokoyama, S, Umezawa, N, Higuchi, T, Umehara, T. 登録日 2016-11-14 公開日 2017-04-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1. Bioorg. Med. Chem., 25, 2017
5H6R	Crystal structure of LSD1-CoREST in complex with peptide 13 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ... 著者 Kkuchi, M, Amano, Y, Sato, S, Yokoyama, S, Umezawa, N, Higuchi, T, Umehara, T. 登録日 2016-11-14 公開日 2017-04-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1. Bioorg. Med. Chem., 25, 2017
5JJ0	Structure of G9a SET-domain with Histone H3K9M peptide and excess SAH 分子名称: Histone H3K9M mutant peptide, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ... 著者 Jayaram, H, Bellon, S.F, Poy, F. 登録日 2016-04-22 公開日 2016-07-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3. Proc.Natl.Acad.Sci.USA, 113, 2016
5DWQ	Crystal structure of CARM1, sinefungin, and methylated H3 peptide (R17) 分子名称: GLYCEROL, Histone-arginine methyltransferase CARM1, SINEFUNGIN, ... 著者 Boriack-Sjodin, P.A. 登録日 2015-09-22 公開日 2015-11-25 最終更新日 2016-03-30 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Structural Insights into Ternary Complex Formation of Human CARM1 with Various Substrates. Acs Chem.Biol., 11, 2016

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