4OUC

Structure of human haspin in complex with histone H3 substrate

Summary for 4OUC

• Entry DOI: 10.2210/pdb4ouc/pdb
• Descriptor: Serine/threonine-protein kinase haspin, Histone H3.2, SODIUM ION, ... (7 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, transferase, histone, kinase substrate complex, chromatin regulator
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q8TF76 Q71DI3
• Total number of polymer chains: 2
• Total formula weight: 43040.55

Authors

Chaikuad, A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2014-02-15, release date: 2014-04-16, Last modification date: 2023-09-20)

• Primary citation: Maiolica, A.,de Medina-Redondo, M.,Schoof, E.M.,Chaikuad, A.,Villa, F.,Gatti, M.,Jeganathan, S.,Lou, H.J.,Novy, K.,Hauri, S.,Toprak, U.H.,Herzog, F.,Meraldi, P.,Penengo, L.,Turk, B.E.,Knapp, S.,Linding, R.,Aebersold, R.; Modulation of the chromatin phosphoproteome by the haspin protein kinase.; Mol Cell Proteomics, 13:1724-1740, 2014; PubMed: 24732914; DOI: 10.1074/mcp.M113.034819

Experimental method

X-RAY DIFFRACTION (1.9 Å)