3GL6

Crystal structure of JARID1A-PHD3 complexed with H3(1-9)K4me3 peptide

Summary for 3GL6

Entry DOI	10.2210/pdb3gl6/pdb
Descriptor	Histone demethylase JARID1A, Histone H3, ZINC ION, ... (4 entities in total)
Functional Keywords	phd finger, h3(1-9)k4me3 peptide, leukemia, alternative splicing, chromatin regulator, developmental protein, dioxygenase, iron, metal-binding, nucleus, oxidoreductase, phosphoprotein, polymorphism, transcription, transcription regulation, zinc, zinc-finger, chromosomal protein, dna-binding, nucleosome core
Biological source	Homo sapiens (human) More
Cellular location	Nucleus, nucleolus: P29375
Total number of polymer chains	2
Total formula weight	7104.05
Authors	Wang, Z.,Song, J.,Patel, D.J. (deposition date: 2009-03-11, release date: 2009-05-05, Last modification date: 2011-07-13)
Primary citation	Wang, G.G.,Song, J.,Wang, Z.,Dormann, H.L.,Casadio, F.,Li, H.,Luo, J.L.,Patel, D.J.,Allis, C.D. Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature, 459:847-851, 2009 Cited by PubMed: 19430464 DOI: 10.1038/nature08036 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation