3RD2
 
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2JXX
 | | NMR solution structure of Ubiquitin-like domain of NFATC2IP. Northeast Structural Genomics Consortium target HR5627 | | 分子名称: | NFATC2-interacting protein | | 著者 | Doherty, R.S, Dhe-Paganon, S, Fares, C, Lemak, A, Butler, C, Srisailam, S, Karra, M, Yee, A, Edwards, A.M, Weigelt, J, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC) | | 登録日 | 2007-11-30 | | 公開日 | 2007-12-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of Ubiquitin-like domain of NFATC2IP.
TO BE PUBLISHED
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6F6P
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6FU5
 | | Structure of the kinase domain of human RIPK2 in complex with the inhibitor CSLP18 | | 分子名称: | Receptor-interacting serine/threonine-protein kinase 2, ~{N}-[5-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-2-methoxy-phenyl]propane-1-sulfonamide | | 著者 | Pinkas, D.M, Bufton, J.C, Kupinska, K, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N. | | 登録日 | 2018-02-26 | | 公開日 | 2018-04-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.26 Å) | | 主引用文献 | Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling.
EMBO J., 37, 2018
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2L76
 | | Solution NMR structure of human NFATC2IP ubiquitin-like domain, NFATC2IP_244_338, NESG target HT65A/OCSP target hs00387_244_338/SGC-toronto | | 分子名称: | NFATC2-interacting protein | | 著者 | Wu, B, Yee, A, Houliston, S, Doherty, R, Semesi, A, Dhe-Paganon, S, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP) | | 登録日 | 2010-12-03 | | 公開日 | 2010-12-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Human NFATC2IP ubiquitin-like domains
To be Published
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3BQO
 | | Crystal Structure of TRF1 TRFH domain and TIN2 peptide complex | | 分子名称: | TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 1 | | 著者 | Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M. | | 登録日 | 2007-12-20 | | 公開日 | 2008-02-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
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7F4U
 | | Cryo-EM structure of TELO2-TTI1-TTI2 complex | | 分子名称: | TELO2-interacting protein 1 homolog, TELO2-interacting protein 2, Telomere length regulation protein TEL2 homolog | | 著者 | Cho, Y, Kim, Y. | | 登録日 | 2021-06-21 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structure of the Human TELO2-TTI1-TTI2 Complex.
J.Mol.Biol., 434, 2022
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4P6Q
 | | The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA Recognition Motifs | | 分子名称: | Msx2-interacting protein, SULFATE ION | | 著者 | Arieti, F, Gabus, C, Tambalo, M, Huet, T, Round, A, Thore, S. | | 登録日 | 2014-03-25 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA recognition motifs.
Nucleic Acids Res., 42, 2014
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2N83
 | | p75NTR DD:RIP2 CARD | | 分子名称: | Receptor-interacting serine/threonine-protein kinase 2, Tumor necrosis factor receptor superfamily member 16 | | 著者 | Lin, Z, Ibanez, C.F. | | 登録日 | 2015-10-02 | | 公開日 | 2015-12-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis of death domain signaling in the p75 neurotrophin receptor
Elife, 4, 2015
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6RLN
 | | Crystal structure of RIP1 kinase in complex with GSK3145095 | | 分子名称: | Receptor-interacting serine/threonine-protein kinase 1, ~{N}-[(3~{S})-7,9-bis(fluoranyl)-2-oxidanylidene-1,3,4,5-tetrahydro-1-benzazepin-3-yl]-3-(phenylmethyl)-1~{H}-1,2,4-triazole-5-carboxamide | | 著者 | Thorpe, J.H, Harris, P.A. | | 登録日 | 2019-05-02 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer.
Acs Med.Chem.Lett., 10, 2019
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6O4Z
 | | Structure of HLA-A2:01 with peptide MM92 | | 分子名称: | Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... | | 著者 | Ying, G, Bitra, A, Zajonc, D.M. | | 登録日 | 2019-03-01 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Anin silico-in vitroPipeline Identifying an HLA-A*02:01+KRAS G12V+Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients.
Front Immunol, 10, 2019
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6O51
 | | Structure of HLA-A2:01 with peptide MM90 | | 分子名称: | Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... | | 著者 | Ying, G, Bitra, A, Zajonc, D.M. | | 登録日 | 2019-03-01 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Anin silico-in vitroPipeline Identifying an HLA-A*02:01+KRAS G12V+Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients.
Front Immunol, 10, 2019
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4V57
 | | Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin and neomycin. | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Borovinskaya, M.A, Shoji, S, Holton, J.M, Fredrick, K, Cate, J.H.D. | | 登録日 | 2007-07-21 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | A steric block in translation caused by the antibiotic spectinomycin.
Acs Chem.Biol., 2, 2007
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4ZFF
 | | Dual-acting Fab 5A12 in complex with VEGF | | 分子名称: | Fragment antigen binding (Fab) 5A12 Heavy chain, Fragment antigen binding (Fab) 5A12 Light chain, SULFATE ION, ... | | 著者 | Harris, S.F, Wu, P. | | 登録日 | 2015-04-21 | | 公開日 | 2015-07-01 | | 最終更新日 | 2015-09-16 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Deep Sequencing-guided Design of a High Affinity Dual Specificity Antibody to Target Two Angiogenic Factors in Neovascular Age-related Macular Degeneration.
J.Biol.Chem., 290, 2015
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3BU8
 | | Crystal Structure of TRF2 TRFH domain and TIN2 peptide complex | | 分子名称: | TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 2 | | 著者 | Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M. | | 登録日 | 2008-01-02 | | 公開日 | 2008-02-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
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7EB9
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2FO5
 | | Crystal structure of recombinant barley cysteine endoprotease B isoform 2 (EP-B2) in complex with leupeptin | | 分子名称: | ACE-LEU-LEU-argininal (leupeptin), Cysteine proteinase EP-B 2, SULFATE ION | | 著者 | Bethune, M.T, Strop, P, Brunger, A.T, Khosla, C. | | 登録日 | 2006-01-12 | | 公開日 | 2006-07-18 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Heterologous Expression, Purification, Refolding, and Structural-Functional Characterization of EP-B2, a Self-Activating Barley Cysteine Endoprotease.
Chem.Biol., 13, 2006
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3VFK
 | | The structure of monodechloro-teicoplanin in complex with its ligand, using ubiquitin as a ligand carrier | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, 8-METHYLNONANOIC ACID, ... | | 著者 | Economou, N.J, Weeks, S.D, Grasty, K.C, Loll, P.J. | | 登録日 | 2012-01-09 | | 公開日 | 2013-01-09 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the complex between teicoplanin and a bacterial cell-wall peptide: use of a carrier-protein approach.
Acta Crystallogr.,Sect.D, 69, 2013
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5DU2
 | | Structural analysis of EspG2 glycosyltransferase | | 分子名称: | EspG2 glycosyltransferase | | 著者 | Michalska, K, Elshahawi, S.I, Bigelow, L, Babnigg, G, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2015-09-18 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural analysis of EspG2 glycosyltransferase
To Be Published
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7XPR
 | | Crystal structrue of SeMet-MtdL:GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Transglycosylse | | 著者 | Li, F.D, He, C. | | 登録日 | 2022-05-05 | | 公開日 | 2023-03-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structures of the NDP-pyranose mutase belonging to glycosyltransferase family 75 reveal residues important for Mn 2+ coordination and substrate binding.
J.Biol.Chem., 299, 2023
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7XPS
 | | Crystal structrue of MtdL:GDP:Mn | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, Transglycosylse | | 著者 | Li, F.D, He, C. | | 登録日 | 2022-05-05 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structures of the NDP-pyranose mutase belonging to glycosyltransferase family 75 reveal residues important for Mn 2+ coordination and substrate binding.
J.Biol.Chem., 299, 2023
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7XPT
 | | Crystal structrue of MtdL:GDP:Mn soaked with GDP-Glc | | 分子名称: | GDP-ALPHA-D-GLUCOSE, MANGANESE (II) ION, Transglycosylse | | 著者 | Li, F.D, He, C. | | 登録日 | 2022-05-05 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of the NDP-pyranose mutase belonging to glycosyltransferase family 75 reveal residues important for Mn 2+ coordination and substrate binding.
J.Biol.Chem., 299, 2023
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7XPU
 | | crystal structure of MtdL-S228A-His soaked GDP-Fucp and Mn | | 分子名称: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE, MANGANESE (II) ION, ... | | 著者 | Li, F.D, He, C. | | 登録日 | 2022-05-05 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structures of the NDP-pyranose mutase belonging to glycosyltransferase family 75 reveal residues important for Mn 2+ coordination and substrate binding.
J.Biol.Chem., 299, 2023
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1ZR7
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4V56
 | | Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin. | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Borovinskaya, M.A, Shoji, S, Holton, J.M, Fredrick, K, Cate, J.H.D. | | 登録日 | 2007-07-21 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.93 Å) | | 主引用文献 | A steric block in translation caused by the antibiotic spectinomycin.
Acs Chem.Biol., 2, 2007
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