Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin.

This is a large structure.

Summary for 4V56

Related2QOV 2QOW 2QOX
Integrates2QOU 2QOV 2QOW 2QOX
Descriptor16S rRNA, 30S ribosomal protein S3, 30S ribosomal protein S4, ... (56 entities in total)
Functional Keywordsrna-protein complex, ribonucleoprotein, ribosomal protein, rna-binding, rrna-binding, antibiotic resistance, repressor, transcription, transcription regulation, transcription termination, translation regulation, acetylation, trna-binding, methylation, endonuclease, hydrolase, nuclease, ribosome
Biological sourceEscherichia coli
Total number of polymer chains104
Total molecular weight4295842.3
Borovinskaya, M.A.,Shoji, S.,Holton, J.M.,Fredrick, K.,Cate, J.H.D. (deposition date: 2007-07-21, release date: 2014-07-09, Last modification date: 2014-12-10)
Primary citation
Borovinskaya, M.A.,Shoji, S.,Holton, J.M.,Fredrick, K.,Cate, J.H.
A steric block in translation caused by the antibiotic spectinomycin.
Acs Chem.Biol., 2:545-552, 2007
PubMed: 17696316 (PDB entries with the same primary citation)
DOI: 10.1021/cb700100n
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.2713812.5%17.9%10.0%0.51MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report