PDB: 8861 件ウェブページステータス検索Chemie searchBIRD

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7WLR	Cryo-EM structure of the nucleosome containing Komagataella pastoris histones 分子名称: DNA (145-MER), Histone H2A, Histone H2B, ... 著者 Fukushima, Y, Hatazawa, S, Hirai, S, Kujirai, T, Takizawa, Y, Kurumizaka, H. 登録日 2022-01-13 公開日 2022-07-13 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Structural and biochemical analyses of the nucleosome containing Komagataella pastoris histones. J.Biochem., 172, 2022
5MJ4	INTERLEUKIN-23 COMPLEX WITH AN ANTAGONISTIC ALPHABODY, CRYSTAL FORM 2 分子名称: ALPHABODY MA12, Interleukin-12 subunit beta, Interleukin-23 subunit alpha, ... 著者 Desmet, J, Verstraete, K, Bloch, Y, Lorent, E, Wen, Y, Devreese, B, Vandenbroucke, K, Loverix, S, Hettmann, T, Deroo, S, Somers, K, Henderikx, P, Lasters, I, Savvides, S. 登録日 2016-11-29 公開日 2017-01-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 STRUCTURAL BASIS OF IL-23 ANTAGONISM BY AN ALPHABODY PROTEIN Nature Communications, 5, 2014
5MJ3	INTERLEUKIN-23 COMPLEX WITH AN ANTAGONISTIC ALPHABODY, CRYSTAL FORM 1 分子名称: ALPHABODY MA12, Interleukin-12 subunit beta, Interleukin-23 subunit alpha, ... 著者 Desmet, J, Verstraete, K, Bloch, Y, Lorent, E, Wen, Y, Devreese, B, Vandenbroucke, K, Loverix, S, Hettmann, T, Deroo, S, Somers, K, Hendrikx, P, Lasters, I, Savvides, S.N. 登録日 2016-11-29 公開日 2017-01-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Structural Basis Of Il-23 Antagonism By An Alphabody Protein Scaffold. Nat Commun, 5, 2014
6VCD	Cryo-EM structure of IRP2-FBXL5-SKP1 complex 分子名称: F-box/LRR-repeat protein 5, FE2/S2 (INORGANIC) CLUSTER, Iron-responsive element binding protein 2, ... 著者 Wang, H, Shi, H, Zheng, N. 登録日 2019-12-20 公開日 2020-08-05 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster. Mol.Cell, 78, 2020
8C03	Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy12 in outward-facing conformation 分子名称: 2-[2-[2-(1~{H}-benzimidazol-2-yl)ethylamino]ethyl]-~{N}-[(3-fluoranylpyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide, Solute carrier family 40 member 1 著者 Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. 登録日 2022-12-15 公開日 2023-03-22 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.89 Å) 主引用文献 Structures of ferroportin in complex with its specific inhibitor vamifeport. Elife, 12, 2023
8BZY	Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy3 in occluded conformation 分子名称: 2-[2-[2-(1~{H}-benzimidazol-2-yl)ethylamino]ethyl]-~{N}-[(3-fluoranylpyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide, DIUNDECYL PHOSPHATIDYL CHOLINE, Solute carrier family 40 member 1, ... 著者 Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. 登録日 2022-12-15 公開日 2023-03-22 最終更新日 2023-05-24 実験手法 ELECTRON MICROSCOPY (3.24 Å) 主引用文献 Structures of ferroportin in complex with its specific inhibitor vamifeport. Elife, 12, 2023
8C02	Structure of SLC40/ferroportin in complex with synthetic nanobody Sy3 in occluded conformation 分子名称: Solute carrier family 40 member 1, Sybody3 著者 Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. 登録日 2022-12-15 公開日 2023-03-22 最終更新日 2023-03-29 実験手法 ELECTRON MICROSCOPY (4.09 Å) 主引用文献 Structures of ferroportin in complex with its specific inhibitor vamifeport. Elife, 12, 2023
5BWM	The complex structure of C3cer exoenzyme and GDP bound RhoA (NADH-bound state) 分子名称: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ADP-ribosyltransferase, ... 著者 Toda, A, Tsurumura, T, Yoshida, T, Tsuge, H. 登録日 2015-06-08 公開日 2015-06-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure. J.Biol.Chem., 290, 2015
3QB7	Interleukin-4 mutant RGA bound to cytokine receptor common gamma 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ... 著者 Bates, D.L, Junttila, I.S, Creusot, R.J, Moraga, I, Lupardus, P, Fathman, C.G, Paul, W.E, Garcia, K.C. 登録日 2011-01-12 公開日 2012-04-25 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.245 Å) 主引用文献 Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines. Nat.Chem.Biol., 8, 2012
2C9O	3D Structure of the human RuvB-like helicase RuvBL1 分子名称: ADENOSINE-5'-DIPHOSPHATE, RUVB-LIKE 1 著者 Matias, P.M, Gorynia, S, Donner, P, Carrondo, M.A. 登録日 2005-12-14 公開日 2006-10-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the human AAA+ protein RuvBL1. J. Biol. Chem., 281, 2006
5VFT	Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome 分子名称: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ... 著者 Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y. 登録日 2017-04-09 公開日 2018-07-18 実験手法 ELECTRON MICROSCOPY (7 Å) 主引用文献 Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome. Nat Commun, 9, 2018
1NHA	Solution Structure of the Carboxyl-Terminal Domain of RAP74 and NMR Characterization of the FCP-Binding Sites of RAP74 and CTD of RAP74, the subunit of Human TFIIF 分子名称: Transcription initiation factor IIF, alpha subunit 著者 Nguyen, B.D, Chen, H.T, Kobor, M.S, Greenblatt, J, Legault, P, Omichinski, J.G. 登録日 2002-12-19 公開日 2003-02-25 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the Carboxyl-Terminal Domain of RAP74 and NMR Characterization of the FCP1-Binding Sites of RAP74 and Human TFIIB. Biochemistry, 42, 2003
2Z9G	Complex structure of SARS-CoV 3C-like protease with PMA 分子名称: 3C-like proteinase, BENZENE, MERCURY (II) ION 著者 Lee, C.C, Wang, A.H. 登録日 2007-09-19 公開日 2007-12-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors. Febs Lett., 581, 2007
5ZHX	Crystal structure of SmgGDS-558 and farnesylated RhoA complex 分子名称: FARNESYL, Rap1 GTPase-GDP dissociation stimulator 1, Transforming protein RhoA 著者 Shimizu, H, Toma-Fukai, S, Shimizu, T. 登録日 2018-03-13 公開日 2018-09-05 最終更新日 2018-10-03 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 GEF mechanism revealed by the structure of SmgGDS-558 and farnesylated RhoA complex and its implication for a chaperone mechanism. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2Z9J	Complex structure of SARS-CoV 3C-like protease with EPDTC 分子名称: 3C-like proteinase, DIMETHYL SULFOXIDE, zinc(II)hydrogensulfide 著者 Lee, C.C, Wang, A.H. 登録日 2007-09-20 公開日 2007-12-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors. Febs Lett., 581, 2007
7Z8S	Mot1:TBP:DNA - post hydrolysis state 分子名称: DNA (36-MER), Helicase-like protein, Putative tata-box binding protein 著者 Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. 登録日 2022-03-18 公開日 2023-03-29 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1. Nat.Struct.Mol.Biol., 30, 2023
7Z7N	Mot1E1434Q:TBP:DNA - substrate recognition state 分子名称: DNA (36-MER), Helicase-like protein, Putative tata-box binding protein 著者 Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. 登録日 2022-03-16 公開日 2023-03-29 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (5.1 Å) 主引用文献 Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1. Nat.Struct.Mol.Biol., 30, 2023
7ZB5	Mot1(1-1836):TBP:DNA - post-hydrolysis complex dimer 分子名称: DNA (36-MER), Helicase-like protein, Putative tata-box binding protein 著者 Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. 登録日 2022-03-23 公開日 2023-04-05 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1. Nat.Struct.Mol.Biol., 30, 2023
7ZKE	Mot1:TBP:DNA - pre-hydrolysis state 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (36-MER), ... 著者 Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. 登録日 2022-04-12 公開日 2023-04-26 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1. Nat.Struct.Mol.Biol., 30, 2023
5JHH	Crystal structure of the ternary complex between the human RhoA, its inhibitor and the DH/PH domain of human ARHGEF11 分子名称: 3-{3-[ethyl(quinolin-2-yl)amino]phenyl}propanoic acid, GLYCEROL, Rho guanine nucleotide exchange factor 11, ... 著者 Lv, Z, Wang, R, Ma, L, Miao, Q, Wu, J, Yan, Z, Li, J, Miao, L, Wang, F. 登録日 2016-04-21 公開日 2017-04-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and PDZRhoGEF To Be Published
7AUV	The structure of ERK2 in complex with dual inhibitor ASTX029 分子名称: (2~{R})-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-[(1~{S})-1-(3-fluoranyl-5-methoxy-phenyl)-2-oxidanyl-ethyl]propanamide, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ... 著者 O'Reilly, M. 登録日 2020-11-03 公開日 2021-10-06 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 ASTX029, a Novel Dual-mechanism ERK Inhibitor, Modulates Both the Phosphorylation and Catalytic Activity of ERK. Mol.Cancer Ther., 20, 2021
5HRH	The crystal structure of AsfvPolX(H115F/R127A mutant): 1nt-gap(P) DNA2:dGTP ternary complex 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*TP*TP*CP*TP*AP*TP*GP*TP*GP*TP*AP*CP*TP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*AP*GP*TP*AP*CP*A*)-3'), ... 著者 Chen, Y.Q, Zhang, J, Gan, J.H. 登録日 2016-01-23 公開日 2017-01-18 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The crystal structure of Se-AsfvPolX(L52/163M mutant) in complex with 1nt-gap DNA1 To Be Published
5HRK	The crystal structure of AsfvPolX(H115F mutant): 1nt-gap(P) DNA2:dGTP ternary complex 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*TP*TP*CP*TP*AP*TP*GP*TP*GP*TP*AP*CP*TP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*AP*GP*TP*AP*CP*A)-3'), ... 著者 Chen, Y.Q, Zhang, J, Gan, J.H. 登録日 2016-01-23 公開日 2017-01-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The crystal structure of Se-AsfvPolX(L52/163M mutant) in complex with 1nt-gap DNA1 To Be Published
8BI7	Binary structure of 14-3-3s and PKR phosphopeptide 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, PKR phosphopeptide 著者 Somsen, B.A, Ottmann, C. 登録日 2022-11-01 公開日 2023-03-29 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERR gamma Protein-Protein Interaction as a Molecular Glue Drug Discovery Approach. J.Am.Chem.Soc., 145, 2023
5HRF	The crystal structure of AsfvPolX: DNA5: dGTP ternary complex 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*GP*AP*TP*CP*CP*T*)-3'), DNA polymerase beta-like protein, ... 著者 Chen, Y.Q, Zhang, J, Gan, J.H. 登録日 2016-01-23 公開日 2017-01-18 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The crystal structure of Se-AsfvPolX(L52/163M mutant) in complex with 1nt-gap DNA1 To Be Published

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