4YR8
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![BU of 4yr8 by Molmil](/molmil-images/mine/4yr8) | Crystal structure of JNK in complex with a regulator protein | 分子名称: | CHLORIDE ION, Dual specificity protein phosphatase 16, Mitogen-activated protein kinase 8 | 著者 | Liu, X, Wang, J, Wu, J.W, Wang, Z.X. | 登録日 | 2015-03-14 | 公開日 | 2016-03-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation. Nat Commun, 7, 2016
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1X67
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![BU of 1x67 by Molmil](/molmil-images/mine/1x67) | Solution structure of the cofilin homology domain of HIP-55 (drebrin-like protein) | 分子名称: | Drebrin-like protein | 著者 | Goroncy, A.K, Kigawa, T, Koshiba, S, Sato, M, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-05-17 | 公開日 | 2005-11-17 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structures of actin depolymerizing factor homology domains. Protein Sci., 18, 2009
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1X95
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![BU of 1x95 by Molmil](/molmil-images/mine/1x95) | Solution structure of the DNA-hexamer ATGCAT complexed with DNA Bis-intercalating Anticancer Drug XR5944 (MLN944) | 分子名称: | 1-METHYL-9-[12-(9-METHYLPHENAZIN-10-IUM-1-YL)-12-OXO-2,11-DIAZA-5,8-DIAZONIADODEC-1-ANOYL]PHENAZIN-10-IUM, 5'-D(*AP*TP*GP*CP*AP*T)-3' | 著者 | Dai, J, Punchihewa, C, Mistry, P, Ooi, A.T, Yang, D. | 登録日 | 2004-08-19 | 公開日 | 2004-09-28 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Novel DNA bis-intercalation by MLN944, a potent clinical bisphenazine anticancer drug. J.Biol.Chem., 279, 2004
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3DGQ
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8JDM
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![BU of 8jdm by Molmil](/molmil-images/mine/8jdm) | Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated state) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2023-05-14 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.67 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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8JDL
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![BU of 8jdl by Molmil](/molmil-images/mine/8jdl) | Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2023-05-14 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.42 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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8JDJ
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![BU of 8jdj by Molmil](/molmil-images/mine/8jdj) | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2023-05-14 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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8JDK
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![BU of 8jdk by Molmil](/molmil-images/mine/8jdk) | Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | 登録日 | 2023-05-14 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | 主引用文献 | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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2C1N
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![BU of 2c1n by Molmil](/molmil-images/mine/2c1n) | Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3 | 分子名称: | 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE | 著者 | Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C. | 登録日 | 2005-09-16 | 公開日 | 2005-11-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3. Mol.Cell, 20, 2005
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2C1J
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![BU of 2c1j by Molmil](/molmil-images/mine/2c1j) | Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3 | 分子名称: | 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE | 著者 | Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C. | 登録日 | 2005-09-15 | 公開日 | 2005-11-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3. Mol.Cell, 20, 2005
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7OGN
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![BU of 7ogn by Molmil](/molmil-images/mine/7ogn) | Crystal structure of T2R-TTL -mebendazole complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | 著者 | Oliva, M.A, Bonato, F, Diaz, J.F. | 登録日 | 2021-05-07 | 公開日 | 2022-04-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Effect of Clinically Used Microtubule Targeting Drugs on Viral Infection and Transport Function. Int J Mol Sci, 23, 2022
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7NXO
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7NXN
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7NY2
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2WAJ
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![BU of 2waj by Molmil](/molmil-images/mine/2waj) | Crystal structure of human Jnk3 complexed with a 1-aryl-3,4- dihydroisoquinoline inhibitor | 分子名称: | 1-(3-BROMOPHENYL)-7-CHLORO-6-METHOXY-3,4-DIHYDROISOQUINOLINE, MITOGEN-ACTIVATED PROTEIN KINASE 10 | 著者 | Bax, B.D, Christopher, J.A, Jones, E.J, Mosley, J.E. | 登録日 | 2009-02-08 | 公開日 | 2009-03-31 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | 1-Aryl-3,4-Dihydroisoquinoline Inhibitors of Jnk3. Bioorg.Med.Chem.Lett., 19, 2009
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6NFZ
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![BU of 6nfz by Molmil](/molmil-images/mine/6nfz) | Crystal structure of diphosphorylated HPK1 kinase domain in complex with sunitinib in the active state. | 分子名称: | Mitogen-activated protein kinase kinase kinase kinase 1, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide | 著者 | Johnson, E, McTigue, M, Cronin, C.N. | 登録日 | 2018-12-21 | 公開日 | 2019-05-01 | 最終更新日 | 2019-06-26 | 実験手法 | X-RAY DIFFRACTION (2.966 Å) | 主引用文献 | Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation. J.Biol.Chem., 294, 2019
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7CML
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![BU of 7cml by Molmil](/molmil-images/mine/7cml) | The Crystal Structure of human JNK2 from Biortus. | 分子名称: | Mitogen-activated protein kinase 9 | 著者 | Wang, F, Lin, D, Cheng, W, Miao, Q, Huang, Y, Shang, H. | 登録日 | 2020-07-28 | 公開日 | 2020-08-12 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The Crystal Structure of human JNK2 from Biortus. To Be Published
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6NG0
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![BU of 6ng0 by Molmil](/molmil-images/mine/6ng0) | Crystal structure of HPK1 kinase domain T165E,S171E phosphomimetic mutant in complex with sunitinib in the inactive state. | 分子名称: | Mitogen-activated protein kinase kinase kinase kinase 1, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide | 著者 | Johnson, E, McTigue, M, Cronin, C.N. | 登録日 | 2018-12-21 | 公開日 | 2019-05-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation. J.Biol.Chem., 294, 2019
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6NFY
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![BU of 6nfy by Molmil](/molmil-images/mine/6nfy) | Crystal structure of nonphosphorylated, HPK1 kinase domain in complex with sunitinib in the inactive state. | 分子名称: | Mitogen-activated protein kinase kinase kinase kinase 1, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide | 著者 | Johnson, E, McTigue, M, Cronin, C.N. | 登録日 | 2018-12-21 | 公開日 | 2019-05-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation. J.Biol.Chem., 294, 2019
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1P7H
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![BU of 1p7h by Molmil](/molmil-images/mine/1p7h) | Structure of NFAT1 bound as a dimer to the HIV-1 LTR kB element | 分子名称: | 5'-D(*AP*AP*TP*GP*GP*GP*GP*AP*CP*TP*TP*TP*CP*CP*A)-3', 5'-D(*TP*TP*TP*GP*GP*AP*AP*AP*GP*TP*CP*CP*CP*CP*A)-3', Nuclear factor of activated T-cells, ... | 著者 | Giffin, M.J, Stroud, J.C, Bates, D.L, von Koenig, K.D, Hardin, J, Chen, L. | 登録日 | 2003-05-01 | 公開日 | 2003-09-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of NFAT1 bound as a dimer to the HIV-1 LTR kappa B element Nat.Struct.Biol., 10, 2003
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7DVM
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2M6Y
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![BU of 2m6y by Molmil](/molmil-images/mine/2m6y) | The solution structure of the J-domain of human DnaJA1 | 分子名称: | DnaJ homolog subfamily A member 1 | 著者 | Stark, J.L, Mehla, K, Chaika, N, Acton, T.B, Xiao, R, Singh, P.K, Montelione, G.T, Powers, R, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-04-14 | 公開日 | 2013-06-26 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and function of human DnaJ homologue subfamily a member 1 (DNAJA1) and its relationship to pancreatic cancer. Biochemistry, 53, 2014
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4URI
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![BU of 4uri by Molmil](/molmil-images/mine/4uri) | Crystal structure of chitinase-like agglutinin RobpsCRA from Robinia pseudoacacia | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHITINASE-RELATED AGGLUTININ, CHLORIDE ION, ... | 著者 | Sulzenbacher, G, Roig-Zamboni, V, Peumans, W.J, Henrissat, B, van Damme, E.J.M, Bourne, Y. | 登録日 | 2014-06-30 | 公開日 | 2015-03-11 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Basis for Carbohydrate Binding Properties of a Plant Chitinase-Like Agglutinin with Conserved Catalytic Machinery. J.Struct.Biol., 190, 2015
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7WB0
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7WAZ
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![BU of 7waz by Molmil](/molmil-images/mine/7waz) | |