3DGQ
Crystal structure of the glutathione transferase PI enzyme in complex with the bifunctional inhibitor, etharapta
Summary for 3DGQ
| Entry DOI | 10.2210/pdb3dgq/pdb |
| Related | 3DD3 |
| Descriptor | Glutathione S-transferase P, CHLORIDE ION, ETHACRYNIC ACID, ... (7 entities in total) |
| Functional Keywords | transferase, glutathione, detoxification, etharapta, ruthenium, ethacrynic-acid |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 47656.20 |
| Authors | Parker, L.J. (deposition date: 2008-06-15, release date: 2009-04-21, Last modification date: 2023-11-01) |
| Primary citation | Ang, W.H.,Parker, L.J.,De Luca, A.,Juillerat-Jeanneret, L.,Morton, C.J.,Lo Bello, M.,Parker, M.W.,Dyson, P.J. Rational design of an organometallic glutathione transferase inhibitor Angew.Chem.Int.Ed.Engl., 48:3854-3857, 2009 Cited by PubMed: 19396894DOI: 10.1002/anie.200900185 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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