3DGQ
Crystal structure of the glutathione transferase PI enzyme in complex with the bifunctional inhibitor, etharapta
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutathione S-transferase P | polymer | 210 | 23377.8 | 2 | UniProt (P09211) Pfam (PF02798) Pfam (PF14497) | Homo sapiens (Human) | GST class-pi, GSTP1-1, Glutathione transferase PI |
| 2 | C, G (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | D (A) | ETHACRYNIC ACID | non-polymer | 303.1 | 1 | Chemie (EAA) | |||
| 4 | E, I (A, B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 5 | F (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | H (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | J, K (A, B) | water | water | 18.0 | 506 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46755.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 900.7 | |
| All* | Total formula weight | 47656.2 |
