7OGN

Crystal structure of T2R-TTL -mebendazole complex

Summary for 7OGN

• Entry DOI: 10.2210/pdb7ogn/pdb
• Related: 7ODN
• Descriptor: Tubulin alpha-1B chain, GUANOSINE-5'-DIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (15 entities in total)
• Functional Keywords: cytoskeleton, microtubules, tubulin, mebendazole, structural protein
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 6
• Total formula weight: 270894.02

Authors

Oliva, M.A.,Bonato, F.,Diaz, J.F. (deposition date: 2021-05-07, release date: 2022-04-06, Last modification date: 2024-01-31)

• Primary citation: Oliva, M.A.,Tosat-Bitrian, C.,Barrado-Gil, L.,Bonato, F.,Galindo, I.,Garaigorta, U.,Alvarez-Bernad, B.,Paris-Ogayar, R.,Lucena-Agell, D.,Gimenez-Abian, J.F.,Garcia-Dorival, I.,Urquiza, J.,Gastaminza, P.,Diaz, J.F.,Palomo, V.,Alonso, C.; Effect of Clinically Used Microtubule Targeting Drugs on Viral Infection and Transport Function.; Int J Mol Sci, 23:-, 2022; PubMed: 35408808; DOI: 10.3390/ijms23073448

Experimental method

X-RAY DIFFRACTION (2.2 Å)