PDB: 45459 件ウェブページステータス検索Chemie searchBIRD

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2QG4	Crystal structure of human UDP-glucose dehydrogenase product complex with UDP-glucuronate 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Kavanagh, K.L, Guo, K, Bunkoczi, G, Savitsky, P, Pilka, E, Bhatia, C, Niesen, F, Smee, C, Berridge, G, von Delft, F, Weigelt, J, Arrowsmith, C.H, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) 登録日 2007-06-28 公開日 2007-07-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and mechanism of human UDP-glucose 6-dehydrogenase. J.Biol.Chem., 286, 2011
2QL3	Crystal structure of the C-terminal domain of a probable LysR family transcriptional regulator from Rhodococcus sp. RHA1 分子名称: PHOSPHATE ION, Probable transcriptional regulator, LysR family protein 著者 Tan, K, Skarina, T, Kagen, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2007-07-12 公開日 2007-07-24 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The crystal structure of the C-terminal domain of a probable LysR family transcriptional regulator from Rhodococcus sp. RHA1. To be Published
3OPQ	Phosphoribosylaminoimidazole carboxylase with fructose-6-phosphate bound to the central channel of the octameric protein structure. 分子名称: CHLORIDE ION, FORMIC ACID, FRUCTOSE -6-PHOSPHATE, ... 著者 Filippova, E.V, Wawrzak, Z, Kudritska, M, Edwards, A, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-09-01 公開日 2010-11-17 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Phosphoribosylaminoimidazole carboxylase with fructose-6-phosphate bound to the central channel of the octameric protein structure. To be Published
3T52	L29I Mutation in an Aryl Esterase from Pseudomonas fluorescens Leads to Unique Peptide Flip and Increased Activity 分子名称: ACETATE ION, Arylesterase, CHLORIDE ION, ... 著者 Kazlauskas, R.J, Yin, T, Purpero, V.M. 登録日 2011-07-26 公開日 2012-08-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 L29I Mutation in an Aryl Esterase from Pseudomonas fluorescens Leads to Unique Peptide Flip and Increased Activity To be Published
3SOM	crystal structure of human MMACHC 分子名称: 1,2-ETHANEDIOL, 2-AMINO-ETHANETHIOL, 5'-DEOXYADENOSINE, ... 著者 Krojer, T, Froese, D.S, von Delft, F, Muniz, J.R, Gileadi, C, Vollmar, M, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Gravel, R.A, Yue, W.W, Oppermann, U, Structural Genomics Consortium (SGC) 登録日 2011-06-30 公開日 2011-07-27 最終更新日 2015-04-15 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of MMACHC reveals an arginine-rich pocket and a domain-swapped dimer for its B12 processing function. Biochemistry, 51, 2012
2QO1	2.6 Angstrom Crystal Structure of the Complex Between 11-(decyldithiocarbonyloxy)-undecanoic acid and Mycobacterium Tuberculosis FabH. 分子名称: 11-[(MERCAPTOCARBONYL)OXY]UNDECANOIC ACID, 3-oxoacyl-[acyl-carrier-protein] synthase 3, DECANE-1-THIOL 著者 Sachdeva, S, Musayev, F, Alhamadsheh, M, Scarsdale, J.N, Wright, H.T, Reynolds, K.A. 登録日 2007-07-19 公開日 2008-05-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Separate Entrance and Exit Portals for Ligand Traffic in Mycobacterium tuberculosis FabH Chem.Biol., 15, 2008
3P2L	Crystal Structure of ATP-dependent Clp protease subunit P from Francisella tularensis 分子名称: 1,2-ETHANEDIOL, ATP-dependent Clp protease proteolytic subunit, DI(HYDROXYETHYL)ETHER, ... 著者 Kim, Y, Zhou, M, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-10-02 公開日 2010-10-20 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.295 Å) 主引用文献 Crystal Structure of ATP-dependent Clp protease subunit P from Francisella tularensis To be Published
2QQG	Hst2 bound to ADP-HPD, acetyllated histone H4 and nicotinamide 分子名称: 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, Histone H4, NAD-dependent deacetylase HST2, ... 著者 Marmorstein, R, Sanders, B, Zhao, K, Slama, J. 登録日 2007-07-26 公開日 2007-10-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes. Mol.Cell, 25, 2007
3SPE	Crystal structure of the tail sheath protein protease resistant fragment from bacteriophage phiKZ 分子名称: GLYCEROL, PHIKZ029, PHOSPHATE ION 著者 Aksyuk, A.A, Kurochkina, L.P, Fokine, A, Mesyanzhinov, V.V, Rossmann, M.G. 登録日 2011-07-01 公開日 2011-12-14 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.3996 Å) 主引用文献 Structural conservation of the myoviridae phage tail sheath protein fold. Structure, 19, 2011
3FV3	Secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A 分子名称: GLYCEROL, SULFATE ION, Sapp1p-secreted aspartic protease 1, ... 著者 Dostal, J, Brynda, J, Hruskova-Heidingsfeldova, O, Sieglova, I, Pichova, I, Rezacova, P. 登録日 2009-01-15 公開日 2009-05-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The crystal structure of the secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A J.Struct.Biol., 167, 2009
3SPL	Crystal structure of aprataxin ortholog Hnt3 in complex with DNA and AMP 分子名称: ADENOSINE MONOPHOSPHATE, Aprataxin-like protein, DNA (5'-D(*GP*TP*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*AP*TP*GP*AP*G)-3'), ... 著者 Gong, Y, Zhu, D, Ding, J, Dou, C, Ren, X, Jiang, T, Wang, D. 登録日 2011-07-02 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA Nat.Struct.Mol.Biol., 18, 2011
3OLA	Poliovirus polymerase elongation complex with 2'-deoxy-CTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(*GP*CP*CP*CP*GP*GP*AP*CP*GP*AP*GP*AP*GP*A)-D(P*C)-3'), ... 著者 Gong, P, Peersen, O.B. 登録日 2010-08-25 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.USA, 107, 2010
3SYC	Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) D228N mutant 分子名称: G protein-activated inward rectifier potassium channel 2, POTASSIUM ION 著者 Whorton, M.R, MacKinnon, R. 登録日 2011-07-16 公開日 2011-10-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.41 Å) 主引用文献 Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation by G Proteins, PIP(2), and Sodium. Cell(Cambridge,Mass.), 147, 2011
3OOW	Octameric structure of the phosphoribosylaminoimidazole carboxylase catalytic subunit from Francisella tularensis subsp. tularensis SCHU S4. 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, FORMIC ACID, ... 著者 Filippova, E.V, Wawrzak, Z, Kudritska, M, Edwards, A, Savchenko, A, Anderson, F.W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-08-31 公開日 2010-09-15 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Octameric structure of the phosphoribosylaminoimidazole carboxylase catalytic subunit from Francisella tularensis subsp. tularensis SCHU S4. To be Published
3FYE	Catalytic core subunits (I and II) of cytochrome c oxidase from Rhodobacter sphaeroides in the reduced state 分子名称: CADMIUM ION, CALCIUM ION, COPPER (I) ION, ... 著者 Qin, L, Mills, D.A, Proshlyakov, D.A, Hiser, C, Ferguson-Miller, S. 登録日 2009-01-22 公開日 2009-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Redox dependent conformational changes in cytochrome c oxidase suggest a gating mechanism for proton uptake. Biochemistry, 48, 2009
3CL0	N1 Neuraminidase H274Y + oseltamivir 分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, Neuraminidase 著者 Collins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J. 登録日 2008-03-18 公開日 2008-05-20 最終更新日 2018-08-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants. Nature, 453, 2008
3OV2	Curcumin synthase 1 from Curcuma longa 分子名称: 1,2-ETHANEDIOL, Curcumin synthase, MALONATE ION 著者 Katsuyama, Y, Miyazono, K, Tanokura, M, Ohnishi, Y, Horinouchi, S. 登録日 2010-09-15 公開日 2010-12-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 A hydrophobic cavity discovered in a curcumin synthase facilitates utilization of a beta-keto acid as an extender substrate for the atypical type III polyleteide synthase To be Published
3SAP	Crystal structure of human carbonic anhydrase isozyme II with 4-{[(5-butyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-{[(5-butylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-06-03 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3SAX	Crystal structure of human carbonic anhydrase isozyme II with 2-chloro-5-{[(5-ethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 2-chloro-5-{[(5-ethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-06-03 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3P1M	Crystal structure of human ferredoxin-1 (FDX1) in complex with iron-sulfur cluster 分子名称: Adrenodoxin, mitochondrial, CITRATE ANION, ... 著者 Chaikuad, A, Johansson, C, Krojer, T, Yue, W.W, Phillips, C, Bray, J.E, Pike, A.C.W, Muniz, J.R.C, Vollmar, M, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Kavanagh, K, Oppermann, U, Structural Genomics Consortium (SGC) 登録日 2010-09-30 公開日 2010-11-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Crystal structure of human ferredoxin-1 (FDX1) in complex with iron-sulfur cluster To be Published
3SFU	crystal structure of murine norovirus RNA dependent RNA polymerase in complex with ribavirin 分子名称: 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, GLYCEROL, MAGNESIUM ION, ... 著者 Kim, K.H, Alam, I. 登録日 2011-06-14 公開日 2012-05-09 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin. Virology, 426, 2012
3SIO	Ac-AChBP ligand binding domain (not including beta 9-10 linker) mutated to human alpha-7 nAChR 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Nemecz, A, Taylor, P.W. 登録日 2011-06-19 公開日 2011-10-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Creating an alpha-7 nicotinic acetylcholine recognition domain from the acetylcholine binding protein: crystallographic and ligand selectivity analyses J.Biol.Chem., 286, 2011
2R8B	The crystal structure of the protein Atu2452 of unknown function from Agrobacterium tumefaciens str. C58 分子名称: SULFATE ION, Uncharacterized protein Atu2452 著者 Tan, K, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2007-09-10 公開日 2007-09-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 The crystal structure of the protein Atu2452 of unknown function from Agrobacterium tumefaciens str. C58. TO BE PUBLISHED
3S8X	Crystal structure of human carbonic anhydrase isozyme II with 4-{[(4-methyl-6-oxo-1,6-dihydro-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-05-31 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3SDK	Structure of yeast 20S open-gate proteasome with Compound 34 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, N-[(2S)-3-(3-tert-butyl-1,2,4-oxadiazol-5-yl)-1-({(2S)-1-[(4-methylbenzyl)amino]-1-oxo-4-phenylbutan-2-yl}amino)-1-oxopropan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide, ... 著者 Sintchak, M.D. 登録日 2011-06-09 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome. Bioorg.Med.Chem.Lett., 20, 2010

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