3SYC

Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) D228N mutant

Summary for 3SYC

Entry DOI	10.2210/pdb3syc/pdb
Related	3SYA 3SYO 3SYP 3SYQ
Descriptor	G protein-activated inward rectifier potassium channel 2, POTASSIUM ION (2 entities in total)
Functional Keywords	ion channel, potassium channel, inward rectification, sodium binding, pip2 binding, g protein binding, metal transport
Biological source	Mus musculus (mouse)
Cellular location	Membrane; Multi-pass membrane protein: P48542
Total number of polymer chains	1
Total formula weight	39295.56
Authors	Whorton, M.R.,MacKinnon, R. (deposition date: 2011-07-16, release date: 2011-10-12, Last modification date: 2023-09-13)
Primary citation	Whorton, M.R.,Mackinnon, R. Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation by G Proteins, PIP(2), and Sodium. Cell(Cambridge,Mass.), 147:199-208, 2011 Cited by PubMed: 21962516 DOI: 10.1016/j.cell.2011.07.046 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.41 Å)

Structure validation