PDB: 436 件ウェブページステータス検索Chemie searchBIRD

---

6B70	Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain and insulin 分子名称: FAB H11-E heavy chain, FAB H11-E light chain, Insulin, ... 著者 Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. 登録日 2017-10-03 公開日 2017-12-27 最終更新日 2021-04-28 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
6BFC	Cryo-EM structure of human insulin degrading enzyme in complex with insulin 分子名称: Insulin, Insulin-degrading enzyme 著者 Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. 登録日 2017-10-26 公開日 2017-12-27 最終更新日 2021-04-28 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
6FF3	Crystal structure of Drosophila neural ectodermal development factor Imp-L1 with Human IGF-I 分子名称: Insulin-like growth factor I, Neural/ectodermal development factor IMP-L2 著者 Brzozowski, A.M, Kulahin, N, Kristensen, O, Schluckebier, G, Meyts, P.D, Viola, C.M. 登録日 2018-01-03 公開日 2018-09-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones. Nat Commun, 9, 2018
6FEY	Crystal structure of Drosophila neural ectodermal development factor Imp-L2 with Drosophila DILP5 insulin 分子名称: Neural/ectodermal development factor IMP-L2, Probable insulin-like peptide 5 著者 Brzozowski, A.M, Kulahin, N, Kristensen, O, Schluckebier, G, Meyts, P.D. 登録日 2018-01-03 公開日 2018-09-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.48 Å) 主引用文献 Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones. Nat Commun, 9, 2018
6CE9	Insulin Receptor ectodomain in complex with two insulin molecules 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. 登録日 2018-02-11 公開日 2018-03-14 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556, 2018
6CEB	Insulin Receptor ectodomain in complex with two insulin molecules - C1 symmetry 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. 登録日 2018-02-11 公開日 2018-03-14 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556, 2018
6CE7	Insulin Receptor ectodomain in complex with one insulin molecule 分子名称: Insulin A chain, Insulin B chain, Insulin receptor, ... 著者 Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. 登録日 2018-02-11 公開日 2018-03-14 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556, 2018
6CK2	Insulin analog containing a YB26W mutation 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Rege, N.K, Yee, V.C, Weiss, M.A. 登録日 2018-02-27 公開日 2018-06-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure-based stabilization of insulin as a therapeutic protein assembly via enhanced aromatic-aromatic interactions. J. Biol. Chem., 293, 2018
6GNQ	Monoclinic crystalline form of human insulin, complexed with meta-cresol 分子名称: 1,2-ETHANEDIOL, Insulin, M-CRESOL, ... 著者 Margiolaki, I, Karavassili, F, Valmas, A, Dimarogona, M, Giannopoulou, A.E, Fili, S, Schluckebier, G, Norrman, M, Beckers, D, Fitch, A.N. 登録日 2018-05-31 公開日 2019-06-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Monoclinic crystalline form of human insulin, complexed with meta-cresol To Be Published
6GV0	Insulin glulisine 分子名称: FORMIC ACID, Insulin, ZINC ION 著者 Chayen, N.E, Helliwell, J.R, Solomon-Gamsu, H.V, Govada, L, Morgan, M, Gillis, R.B, Adams, G. 登録日 2018-06-20 公開日 2019-07-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Analysis of insulin glulisine at the molecular level by X-ray crystallography and biophysical techniques. Sci Rep, 11, 2021
6H3M	The crystal structure of a human seleno-insulin analog 分子名称: Insulin 著者 Lansky, S, Weil-Ktorza, O, Metanis, N, Shoham, G. 登録日 2018-07-19 公開日 2019-08-14 最終更新日 2020-08-26 実験手法 X-RAY DIFFRACTION (1.821 Å) 主引用文献 Substitution of an Internal Disulfide Bridge with a Diselenide Enhances both Foldability and Stability of Human Insulin. Chemistry, 25, 2019
6HN5	Leucine-zippered human insulin receptor ectodomain with single bound insulin - "upper" membrane-distal part 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, ... 著者 Weis, F, Menting, J.G, Margetts, M.B, Chan, S.J, Xu, Y, Tennagels, N, Wohlfart, P, Langer, T, Mueller, C.W, Dreyer, M.K, Lawrence, M.C. 登録日 2018-09-14 公開日 2018-11-21 最終更新日 2022-03-30 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 The signalling conformation of the insulin receptor ectodomain. Nat Commun, 9, 2018
6Q8Q	Bovine Insulin under 2 kbar of argon 分子名称: ARGON, Insulin 著者 Prange, T, Carpentier, P. 登録日 2018-12-16 公開日 2020-01-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Argon-labelling protein crystals by high pressure cooling at 2 kbar To be published
6NWV	Insulin Lispro Analog 分子名称: CHLORIDE ION, GLYCEROL, Insulin A chain, ... 著者 Cruz-Rangel, A, Romero, A, Reyes-Grajeda, J.P. 登録日 2019-02-07 公開日 2020-02-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.601 Å) 主引用文献 Crystal structure of Lispro hexameric insulin analog To Be Published
6O17	Recombinant Human Insulin 分子名称: Insulin chain A, Insulin chain B 著者 Reyes-Grajeda, J.P. 登録日 2019-02-18 公開日 2020-02-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Human WT insulin To Be Published
6QQ7	Bovine insulin at ambient pressure 分子名称: Insulin 著者 Kurpiewska, K, Milaczewska, A, Lewinski, K. 登録日 2019-02-18 公開日 2019-02-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Insulin conformational changes under high pressure in structural studies and molecular dynamics simulations J.Mol.Struct., 2020
6QQG	High pressure structure of bovine insulin (60 MPa) 分子名称: Insulin 著者 Kurpiewska, K, Milaczewska, A, Lewinski, K. 登録日 2019-02-18 公開日 2019-03-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.149 Å) 主引用文献 Insulin conformational changes under high pressure in structural studies and molecular dynamics simulations J.Mol.Struct., 2020
6QRH	High pressure structure of bovine insulin (100 MPa) 分子名称: Insulin 著者 Kurpiewska, K, Milaczewska, A, Lewinski, K. 登録日 2019-02-19 公開日 2019-02-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.152 Å) 主引用文献 Insulin conformational changes under high pressure in structural studies and molecular dynamics simulations J.Mol.Struct., 2020
6QRK	High pressure structure of bovine insulin (200 MPa) 分子名称: Insulin 著者 Kurpiewska, K, Milaczewska, A, Lewinski, K. 登録日 2019-02-19 公開日 2019-03-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.102 Å) 主引用文献 Insulin conformational changes under high pressure in structural studies and molecular dynamics simulations J.Mol.Struct., 2020
6JK8	Cryo-EM structure of the full-length human IGF-1R in complex with insulin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, ... 著者 Zhang, X, Yu, D, Wang, T. 登録日 2019-02-27 公開日 2020-03-04 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Visualization of Ligand-Bound Ectodomain Assembly in the Full-Length Human IGF-1 Receptor by Cryo-EM Single-Particle Analysis. Structure, 28, 2020
6JR3	Crystal structure of insulin hexamer fitted into cryo EM density map where each dimer was kept as rigid body 分子名称: Insulin A chain, Insulin B chain 著者 Sengupta, J, Pathak, B.K, Bhakta, S. 登録日 2019-04-02 公開日 2020-04-22 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (14.5 Å) 主引用文献 Resveratrol as a nontoxic excipient stabilizes insulin in a bioactive hexameric form. J.Comput.Aided Mol.Des., 34, 2020
6OR0	Crystal structure of Insulin from Non-merohedrally twinned crystals 分子名称: Insulin chain A, Insulin chain B 著者 Sevvana, M, Ruf, M, Uson, I, Sheldrick, G.M, Herbst-Irmer, R. 登録日 2019-04-29 公開日 2019-12-11 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Non-merohedral twinning: from minerals to proteins. Acta Crystallogr D Struct Biol, 75, 2019
6K59	Structure of Glargine insulin in 20% acetic acid-d4 (pH 1.9) 分子名称: Glargine Insulin Chain-A, Glargine insulin Chain-B 著者 Ratha, B.N, Kar, R.K, Bhunia, A. 登録日 2019-05-28 公開日 2020-05-06 実験手法 SOLUTION NMR 主引用文献 Molecular Details of a Salt Bridge and Its Role in Insulin Fibrillation by NMR and Raman Spectroscopic Analysis. J.Phys.Chem.B, 124, 2020
6P4Z	Structure of gadolinium-caged cobalt (III) insulin hexamer 分子名称: CHLORIDE ION, COBALT (II) ION, GADOLINIUM ATOM, ... 著者 Tran, T.H, Taylor, S.K, Stojanovic, M.N, Tong, L. 登録日 2019-05-29 公開日 2019-06-12 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Insulin Hexamer-Caged Gadolinium Ion as MRI Contrast-o-phore ChemBioChem, 24, 2018
6RVA	STRUCTURE OF [ASP58]-IGF-I ANALOGUE 分子名称: Insulin-like growth factor I 著者 Jiracek, J, Zakova, L, Socha, O. 登録日 2019-05-31 公開日 2019-10-02 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2 result in receptor- and hormone-specific responses. J.Biol.Chem., 294, 2019

<789101112131415161718>