6FEY

Crystal structure of Drosophila neural ectodermal development factor Imp-L2 with Drosophila DILP5 insulin

Summary for 6FEY

Entry DOI	10.2210/pdb6fey/pdb
Related	2WFV 4CBP
Descriptor	Neural/ectodermal development factor IMP-L2, Probable insulin-like peptide 5, ... (4 entities in total)
Functional Keywords	insulin, insulin binding protein, drosophila, imaginal morphogenesis, peptide binding protein
Biological source	Drosophila melanogaster (Fruit fly) More
Total number of polymer chains	12
Total formula weight	132417.45
Authors	Brzozowski, A.M.,Kulahin, N.,Kristensen, O.,Schluckebier, G.,Meyts, P.D. (deposition date: 2018-01-03, release date: 2018-09-26, Last modification date: 2024-01-17)
Primary citation	Roed, N.K.,Viola, C.M.,Kristensen, O.,Schluckebier, G.,Norrman, M.,Sajid, W.,Wade, J.D.,Andersen, A.S.,Kristensen, C.,Ganderton, T.R.,Turkenburg, J.P.,De Meyts, P.,Brzozowski, A.M. Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones. Nat Commun, 9:3860-3860, 2018 Cited by PubMed: 30242155 DOI: 10.1038/s41467-018-06192-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.48 Å)

Structure validation