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6EN2
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BU of 6en2 by Molmil
Structure of the Tn1549 transposon Integrase (aa 82-397, R225K) in complex with a circular intermediate DNA (CI6b-DNA)
分子名称: DI(HYDROXYETHYL)ETHER, DNA (45-MER), Int protein
著者Rubio-Cosials, A, Barabas, O.
登録日2017-10-04
公開日2018-04-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance.
Cell, 173, 2018
6EN1
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BU of 6en1 by Molmil
Structure of the Tn1549 transposon Integrase (aa 82-397, R225K) in complex with a circular intermediate DNA (CI6a-DNA)
分子名称: DI(HYDROXYETHYL)ETHER, DNA (45-MER), Int protein
著者Rubio-Cosials, A, Barabas, O.
登録日2017-10-04
公開日2018-04-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance.
Cell, 173, 2018
7S37
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BU of 7s37 by Molmil
Cas9:sgRNA (S. pyogenes) in the open-protein conformation
分子名称: CRISPR-associated endonuclease Cas9/Csn1, Single-guide RNA
著者Cofsky, J.C, Soczek, K.M, Knott, G.J, Nogales, E, Doudna, J.A.
登録日2021-09-04
公開日2022-04-20
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献CRISPR-Cas9 bends and twists DNA to read its sequence.
Nat.Struct.Mol.Biol., 29, 2022
1KTQ
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BU of 1ktq by Molmil
DNA POLYMERASE
分子名称: DNA POLYMERASE I
著者Korolev, S, Waksman, G.
登録日1995-08-16
公開日1996-11-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability.
Proc.Natl.Acad.Sci.USA, 92, 1995
7DCI
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BU of 7dci by Molmil
Crystal structure of HSF2 DNA-binding domain in complex with 2-site HSE DNA in the head-to-head orientation
分子名称: DNA (5'-D(*GP*GP*GP*AP*AP*TP*AP*TP*TP*CP*CP*C)-3'), Heat shock factor protein 2, SODIUM ION
著者Wei, L, Wei, L.
登録日2020-10-26
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of HSF2 DNA-binding domain in complex with 2-site HSE DNA in the head-to-head orientation
To Be Published
8HPA
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BU of 8hpa by Molmil
Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in a DNA binding form
分子名称: DNA (5'-D(*CP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*TP*AP*C)-3'), DNA (5'-D(P*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*CP*G)-3'), DNA polymerase, ...
著者Xu, Y, Wu, Y, Zhang, Y, Fan, R, Yang, Y, Li, D, Yang, B, Zhang, Z, Dong, C.
登録日2022-12-12
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Structure of DNA replication machinery from human monkeypox virus
To Be Published
5BT2
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BU of 5bt2 by Molmil
MeCP2 MBD domain (A140V) in complex with methylated DNA
分子名称: DNA (5'-D(*AP*TP*AP*GP*AP*AP*GP*AP*AP*TP*TP*CP*(5CM)P*GP*TP*TP*CP*CP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*GP*GP*AP*AP*(5CM)P*GP*GP*AP*AP*TP*TP*CP*TP*TP*CP*TP*A)-3'), Methyl-CpG-binding protein 2
著者Ho, K.L, Chia, J.Y, Tan, W.S, Ng, C.L, Hu, N.J, Foo, H.L.
登録日2015-06-02
公開日2016-08-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A/T Run Geometry of B-form DNA Is Independent of Bound Methyl-CpG Binding Domain, Cytosine Methylation and Flanking Sequence.
Sci Rep, 6, 2016
9C5Q
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BU of 9c5q by Molmil
Human DNA polymerase theta helicase domain in microhomology annealed state 2, dimer form
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*CP*CP*CP*GP*GP*G)-3'), DNA polymerase theta
著者Ito, F, Li, Z, Chen, X.S.
登録日2024-06-06
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
Biorxiv, 2024
6L5B
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BU of 6l5b by Molmil
The structure of the UdgX mutant H109E at a post-excision state
分子名称: IRON/SULFUR CLUSTER, Uracil DNA glycosylase superfamily protein
著者Xie, W, Tu, J, Zeng, H.
登録日2019-10-22
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.00004983 Å)
主引用文献Structural insights into an MsmUdgX mutant capable of both crosslinking and uracil excision capability.
DNA Repair (Amst), 97, 2021
9ASJ
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BU of 9asj by Molmil
Human DNA polymerase theta helicase domain in complex with AMP-PNP, dimer form
分子名称: DNA polymerase theta, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Ito, F, Li, Z, Chen, X.S.
登録日2024-02-26
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
Biorxiv, 2024
6L5A
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BU of 6l5a by Molmil
The structure of the UdgX mutant H109E at a pre-excision state
分子名称: GLYCEROL, IRON/SULFUR CLUSTER, Uracil DNA glycosylase superfamily protein
著者Xie, W, Tu, J, Zeng, H.
登録日2019-10-22
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.80007327 Å)
主引用文献Structural insights into an MsmUdgX mutant capable of both crosslinking and uracil excision capability.
DNA Repair (Amst), 97, 2021
9ASL
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BU of 9asl by Molmil
Human DNA polymerase theta helicase domain tetramer, apo-form
分子名称: DNA polymerase theta
著者Ito, F, Li, Z, Chen, X.S.
登録日2024-02-26
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
Biorxiv, 2024
9ASK
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BU of 9ask by Molmil
Human DNA polymerase theta helicase domain dimer, apo-form
分子名称: DNA polymerase theta
著者Ito, F, Li, Z, Chen, X.S.
登録日2024-02-26
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
Biorxiv, 2024
5ORQ
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BU of 5orq by Molmil
Crystal structure of designed cPPR-Telo1 in complex with ssDNA
分子名称: DNA (5'-D(P*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), cPPR-Telo1
著者Spahr, H, Rackham, O.
登録日2017-08-16
公開日2018-06-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins.
Nat Commun, 9, 2018
6LTY
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BU of 6lty by Molmil
DNA bound antitoxin HigA3
分子名称: DNA (5'-D(P*CP*CP*AP*CP*GP*AP*GP*AP*TP*AP*TP*AP*AP*CP*CP*TP*AP*GP*AP*G)-3'), DNA (5'-D(P*CP*TP*CP*TP*AP*GP*GP*TP*TP*AP*TP*AP*TP*CP*TP*CP*GP*TP*GP*G)-3'), Putative antitoxin HigA3
著者Park, J.Y, Lee, B.J.
登録日2020-01-23
公開日2020-07-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.28 Å)
主引用文献Induced DNA bending by unique dimerization of HigA antitoxin.
Iucrj, 7, 2020
4WKJ
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BU of 4wkj by Molmil
Crystallographic Structure of a Dodecameric RNA-DNA Hybrid
分子名称: DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), MAGNESIUM ION, RNA (5'-R(*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*C)-3')
著者Davis, R.R, Shaban, N.M, Perrino, F.W, Hollis, T.
登録日2014-10-02
公開日2014-10-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of RNA-DNA duplex provides insight into conformational changes induced by RNase H binding.
Cell Cycle, 14, 2015
9FFF
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BU of 9fff by Molmil
dsDNA-FANCD2-FANCI complex
分子名称: DNA (32-MER), DNA (33-MER), Fanconi anemia complementation group I, ...
著者Alcon, P, Passmore, L.A.
登録日2024-05-23
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献dsDNA-FANCD2-FANCI complex
To Be Published
9FFB
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BU of 9ffb by Molmil
ss-dsDNA-FANCD2-FANCI complex
分子名称: DNA (5'-D(P*CP*GP*AP*TP*GP*TP*CP*TP*CP*TP*AP*GP*AP*CP*AP*GP*CP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*GP*CP*TP*GP*TP*CP*TP*AP*GP*AP*GP*AP*CP*AP*TP*CP*GP*AP*T)-3'), Fanconi anemia complementation group I, ...
著者Alcon, P, Passmore, L.A.
登録日2024-05-22
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献ss-dsDNA-FANCD2-FANCI complex
To Be Published
7D9K
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BU of 7d9k by Molmil
DNA binding domain of human DNA Ligase IV - Wild type
分子名称: DNA ligase 4
著者Maddi, E.R, Raghavan, S.C, Natesh, R.
登録日2020-10-13
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Hypomorphic mutations in human DNA ligase IV lead to compromised DNA binding efficiency, hydrophobicity and thermal stability.
Protein Eng.Des.Sel., 34, 2021
7D9Y
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BU of 7d9y by Molmil
DNA binding domain of human DNA Ligase IV mutant - A3V
分子名称: DNA ligase 4
著者Maddi, E.R, Raghavan, S.C, Natesh, R.
登録日2020-10-14
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Hypomorphic mutations in human DNA ligase IV lead to compromised DNA binding efficiency, hydrophobicity and thermal stability.
Protein Eng.Des.Sel., 34, 2021
6ZHE
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BU of 6zhe by Molmil
Cryo-EM structure of DNA-PK dimer
分子名称: DNA (25-MER), DNA (26-MER), DNA (27-MER), ...
著者Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L.
登録日2020-06-23
公開日2020-10-21
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (7.24 Å)
主引用文献Dimers of DNA-PK create a stage for DNA double-strand break repair.
Nat.Struct.Mol.Biol., 28, 2021
6ZHA
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BU of 6zha by Molmil
Cryo-EM structure of DNA-PK monomer
分子名称: DNA, DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-PKcs, X-ray repair cross-complementing protein 5, ...
著者Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L.
登録日2020-06-21
公開日2020-10-21
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Dimers of DNA-PK create a stage for DNA double-strand break repair.
Nat.Struct.Mol.Biol., 28, 2021
3ZH2
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BU of 3zh2 by Molmil
Structure of Plasmodium falciparum lactate dehydrogenase in complex with a DNA aptamer
分子名称: DNA APTAMER, L-LACTATE DEHYDROGENASE
著者Cheung, Y.W, Kwok, J, Law, A.W.L, Watt, R.M, Kotaka, M, Tanner, J.A.
登録日2012-12-20
公開日2013-09-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for Discriminatory Recognition of Plasmodium Lactate Dehydrogenase by a DNA Aptamer
Proc.Natl.Acad.Sci.USA, 110, 2013
8POP
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BU of 8pop by Molmil
HK97 small terminase in complex with DNA
分子名称: DNA (31-MER), Terminase small subunit
著者Chechik, M, Greive, S.J, Antson, A.A, Jenkins, H.T.
登録日2023-07-05
公開日2023-08-09
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for DNA recognition by a viral genome-packaging machine.
Proc.Natl.Acad.Sci.USA, 121, 2024
4R64
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BU of 4r64 by Molmil
Binary complex crystal structure of E295K mutant of DNA polymerase Beta
分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
著者Batra, V.K, Beard, W.A, Wilson, S.H.
登録日2014-08-22
公開日2014-10-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Substrate-induced DNA Polymerase beta Activation.
J.Biol.Chem., 289, 2014

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件を2024-08-28に公開中

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