5ORQ

Crystal structure of designed cPPR-Telo1 in complex with ssDNA

Summary for 5ORQ

• Entry DOI: 10.2210/pdb5orq/pdb
• Descriptor: cPPR-Telo1, DNA (5'-D(P*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3') (3 entities in total)
• Functional Keywords: designer nucleic acid-binding proteins, pentatricopeptide repeat, telomerase, de novo protein
• Biological source: synthetic construct; More
• Total number of polymer chains: 2
• Total formula weight: 43322.75

Authors

Spahr, H.,Rackham, O. (deposition date: 2017-08-16, release date: 2018-06-20)

• Primary citation: Spahr, H.,Chia, T.,Lingford, J.P.,Siira, S.J.,Cohen, S.B.,Filipovska, A.,Rackham, O.; Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins.; Nat Commun, 9:2212-2212, 2018; PubMed: 29880855; DOI: 10.1038/s41467-018-04388-1

Experimental method

X-RAY DIFFRACTION (1.95 Å)