6EN1

Structure of the Tn1549 transposon Integrase (aa 82-397, R225K) in complex with a circular intermediate DNA (CI6a-DNA)

Summary for 6EN1

Entry DOI	10.2210/pdb6en1/pdb
Related	6EMY 6EMZ 6EN0
Descriptor	Int protein, DNA (45-MER), DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
Functional Keywords	transposase protein - dna complex, tyrosine recombinase, y-transposase, tn916-like conjugative transposon, antibiotic resistance transfer, recombination
Biological source	Enterococcus faecalis (Streptococcus faecalis) More
Total number of polymer chains	4
Total formula weight	100423.51
Authors	Rubio-Cosials, A.,Barabas, O. (deposition date: 2017-10-04, release date: 2018-04-04, Last modification date: 2024-01-17)
Primary citation	Rubio-Cosials, A.,Schulz, E.C.,Lambertsen, L.,Smyshlyaev, G.,Rojas-Cordova, C.,Forslund, K.,Karaca, E.,Bebel, A.,Bork, P.,Barabas, O. Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance. Cell, 173:208-220.e20, 2018 Cited by PubMed: 29551265 DOI: 10.1016/j.cell.2018.02.032 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.67 Å)

Structure validation