7S37
Cas9:sgRNA (S. pyogenes) in the open-protein conformation
Summary for 7S37
| Entry DOI | 10.2210/pdb7s37/pdb |
| Related | 7S36 7S38 7S3H |
| EMDB information | 24817 24818 24819 24823 |
| Descriptor | CRISPR-associated endonuclease Cas9/Csn1, Single-guide RNA (2 entities in total) |
| Functional Keywords | dnase, complex, ribonucleoprotein, genome editor, hydrolase-rna complex, hydrolase/rna |
| Biological source | Streptococcus pyogenes serotype M1 More |
| Total number of polymer chains | 2 |
| Total formula weight | 191759.45 |
| Authors | Cofsky, J.C.,Soczek, K.M.,Knott, G.J.,Nogales, E.,Doudna, J.A. (deposition date: 2021-09-04, release date: 2022-04-20, Last modification date: 2022-05-04) |
| Primary citation | Cofsky, J.C.,Soczek, K.M.,Knott, G.J.,Nogales, E.,Doudna, J.A. CRISPR-Cas9 bends and twists DNA to read its sequence. Nat.Struct.Mol.Biol., 29:395-402, 2022 Cited by PubMed: 35422516DOI: 10.1038/s41594-022-00756-0 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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