6ZHA

Cryo-EM structure of DNA-PK monomer

Summary for 6ZHA

• Entry DOI: 10.2210/pdb6zha/pdb
• EMDB information: 11217
• Descriptor: DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-dependent protein kinase catalytic subunit,DNA-PKcs, X-ray repair cross-complementing protein 6, X-ray repair cross-complementing protein 5, ... (5 entities in total)
• Functional Keywords: kinase, dna-pkcs, nhej, dna-repair, dna-pk, dna binding protein, ku70/80
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 639888.61

Authors

Chaplin, A.K.,Hardwick, S.W.,Chirgadze, D.Y.,Blundell, T.L. (deposition date: 2020-06-21, release date: 2020-10-21, Last modification date: 2021-01-20)

• Primary citation: Chaplin, A.K.,Hardwick, S.W.,Liang, S.,Kefala Stavridi, A.,Hnizda, A.,Cooper, L.R.,De Oliveira, T.M.,Chirgadze, D.Y.,Blundell, T.L.; Dimers of DNA-PK create a stage for DNA double-strand break repair.; Nat.Struct.Mol.Biol., 28:13-19, 2021; PubMed: 33077952; DOI: 10.1038/s41594-020-00517-x

Experimental method

ELECTRON MICROSCOPY (3.91 Å)