PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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7TAT	SARS-CoV-2 spike in complex with the S2K146 neutralizing antibody Fab fragment (two receptor-binding domains open) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2K146 Fab heavy chain, ... 著者 Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. 登録日 2021-12-21 公開日 2022-01-12 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry. Science, 375, 2022
6A76	Crystal structure of the Fab fragment of B5209B, a murine monoclonal antibody specific for the fifth immunoglobulin domain (Ig5) of human ROBO1 分子名称: GLYCEROL, Heavy chain of the anti-human Robo1 antibody B5209B Fab, Light chain of the anti-human Robo1 antibody B5209B Fab, ... 著者 Mizohata, E, Nakayama, T, Kado, Y, Inoue, T. 登録日 2018-07-02 公開日 2019-01-30 最終更新日 2019-03-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface. Structure, 27, 2019
6A77	Crystal structure of the fifth immunoglobulin domain (Ig5) of human Robo1 in complex with the Fab fragment of murine monoclonal antibody B5209B 分子名称: Heavy chain of the anti-human Robo1 antibody B5209B Fab, Light chain of the anti-human Robo1 antibody B5209B Fab, Roundabout homolog 1 著者 Mizohata, E, Nakayama, T, Kado, Y, Inoue, T. 登録日 2018-07-02 公開日 2019-01-30 最終更新日 2019-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface. Structure, 27, 2019
6A78	Crystal structure of the fifth immunoglobulin domain (Ig5) of human Robo1 in complex with the scFv fragment of murine monoclonal antibody B5209B 分子名称: Heavy chain and linker region of the anti-human Robo1 antibody B5209B scFv, Light chain region of the anti-human Robo1 antibody B5209B scFv, Roundabout homolog 1, ... 著者 Mizohata, E, Nakayama, T, Kado, Y, Inoue, T. 登録日 2018-07-02 公開日 2019-01-30 最終更新日 2019-03-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface. Structure, 27, 2019
6A79	Crystal structure of the fifth immunoglobulin domain (Ig5) of human Robo1 in complex with the mutant scFv fragment (P103A) of murine monoclonal antibody B5209B 分子名称: Heavy chain of the anti-human Robo1 antibody B5209B scFv, Light chain region of the anti-human Robo1 antibody B5209B scFv, Roundabout homolog 1, ... 著者 Mizohata, E, Nakayama, T, Kado, Y, Yokota, Y, Inoue, T. 登録日 2018-07-02 公開日 2019-01-30 最終更新日 2019-03-20 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface. Structure, 27, 2019
4DVB	The crystal structure of the Fab fragment of pro-uPA antibody mAb-112 分子名称: Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, TETRAETHYLENE GLYCOL 著者 Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. 登録日 2012-02-23 公開日 2013-01-16 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Rezymogenation of active urokinase induced by an inhibitory antibody. Biochem.J., 449, 2013
3J3Z	Structure of MA28-7 neutralizing antibody Fab fragment from electron cryo-microscopy of enterovirus 71 complexed with a Fab fragment 分子名称: MA28-7 neutralizing antibody heavy chain, MA28-7 neutralizing antibody light chain 著者 Lee, H, Cifuente, J.O, Ashley, R.E, Conway, J.F, Makhov, A.M, Tano, Y, Shimizu, H, Nishimura, Y, Hafenstein, S. 登録日 2013-05-21 公開日 2013-08-28 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (23.4 Å) 主引用文献 A strain-specific epitope of enterovirus 71 identified by cryo-electron microscopy of the complex with fab from neutralizing antibody. J.Virol., 87, 2013
2E27	Crystal structure of Fv fragment of anti-ciguatoxin antibody complexed with ABC-ring of ciguatoxin 分子名称: 3,7:6,10:9,14-TRIANHYDRO-2,5,11,12,13-PENTADEOXY-4-O-(METHOXYMETHYL)-L-ARABINO-L-ALLO-TETRADEC-12-ENONIC ACID, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Yokota, A, Tanaka, Y, Tsumoto, K. 登録日 2006-11-08 公開日 2007-11-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Critical contribution of aromatic rings to specific recognition of polyether rings. The case of ciguatoxin CTX3C-ABC and its specific antibody 1C49. J.Biol.Chem., 283, 2008
6WPT	Structure of the SARS-CoV-2 spike glycoprotein in complex with the S309 neutralizing antibody Fab fragment (open state) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 neutralizing antibody heavy chain, ... 著者 Pinto, D, Park, Y.J, Beltramello, M, Walls, A.C, Tortorici, M.A, Bianchi, S, Jaconi, S, Culap, K, Zatta, F, De Marco, A, Peter, A, Guarino, B, Spreafico, R, Cameroni, E, Case, J.B, Chen, R.E, Havenar-Daughton, C, Snell, G, Virgin, H.W, Lanzavecchia, A, Diamond, M.S, Fink, K, Veesler, D, Corti, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2020-04-27 公開日 2020-05-27 最終更新日 2021-05-19 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody. Nature, 583, 2020
6WPS	Structure of the SARS-CoV-2 spike glycoprotein in complex with the S309 neutralizing antibody Fab fragment 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 neutralizing antibody heavy chain, ... 著者 Pinto, D, Park, Y.J, Beltramello, M, Walls, A.C, Tortorici, M.A, Bianchi, S, Jaconi, S, Culap, K, Zatta, F, De Marco, A, Peter, A, Guarino, B, Spreafico, R, Cameroni, E, Case, J.B, Chen, R.E, Havenar-Daughton, C, Snell, G, Virgin, H.W, Lanzavecchia, A, Diamond, M.S, Fink, K, Veesler, D, Corti, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2020-04-27 公開日 2020-05-27 最終更新日 2021-05-19 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody. Nature, 583, 2020
4XAK	Crystal structure of potent neutralizing antibody m336 in complex with MERS Co-V RBD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Heavy chain of neutralizing antibody m336, ... 著者 Zhou, T, Dimtrov, D.S, Ying, T. 登録日 2014-12-15 公開日 2015-08-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody. Nat Commun, 6, 2015
1A4J	DIELS ALDER CATALYTIC ANTIBODY GERMLINE PRECURSOR 分子名称: IMMUNOGLOBULIN, DIELS ALDER CATALYTIC ANTIBODY (HEAVY CHAIN), DIELS ALDER CATALYTIC ANTIBODY (LIGHT CHAIN) 著者 Spiller, B.W, Romesburg, F.E, Schultz, P.G, Stevens, R.C. 登録日 1998-01-30 公開日 1998-05-13 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Immunological origins of binding and catalysis in a Diels-Alderase antibody. Science, 279, 1998
3WII	Crystal structure of the Fab fragment of B2212A, a murine monoclonal antibody specific for the third fibronectin domain (Fn3) of human ROBO1. 分子名称: anti-human ROBO1 antibody B2212A Fab heavy chain, anti-human ROBO1 antibody B2212A Fab light chain 著者 Nakayama, T, Mizohata, E, Yamashita, T, Nagatoishi, S, Nakakido, M, Iwanari, H, Mochizuki, Y, Kado, Y, Yokota, Y, Sato, R, Tsumoto, K, Fujitani, H, Kodama, T, Hamakubo, T, Inoue, T. 登録日 2013-09-12 公開日 2015-01-21 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses Protein Sci., 24, 2015
1JTT	Degenerate interfaces in antigen-antibody complexes 分子名称: FORMIC ACID, Lysozyme, SODIUM ION, ... 著者 Decanniere, K, Transue, T.R, Desmyter, A, Maes, D, Muyldermans, S, Wyns, L. 登録日 2001-08-22 公開日 2001-12-05 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Degenerate interfaces in antigen-antibody complexes. J.Mol.Biol., 313, 2001
1QFU	INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (HEMAGGLUTININ (HA1 CHAIN)), ... 著者 Fleury, D, Gigant, B, Bizebard, T, Daniels, R.S, Skehel, J.J, Knossow, M. 登録日 1999-04-14 公開日 1999-04-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A complex of influenza hemagglutinin with a neutralizing antibody that binds outside the virus receptor binding site. Nat.Struct.Biol., 6, 1999
1ZTX	West Nile Virus Envelope Protein DIII in complex with neutralizing E16 antibody Fab 分子名称: Envelope protein, Heavy Chain of E16 Antibody, Light Chain of E16 Antibody 著者 Nybakken, G.E, Oliphant, T, Diamond, M.S, Fremont, D.H. 登録日 2005-05-27 公開日 2005-10-04 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis of West Nile virus neutralization by a therapeutic antibody. Nature, 437, 2005
3QCT	Crystal structure of the humanized apo LT3015 anti-lysophosphatidic acid antibody Fab fragment 分子名称: LT3015 antibody Fab fragment, heavy chain, light chain, ... 著者 Fleming, J.K, Wojciak, J.M, Campbell, M.-A, Huxford, T. 登録日 2011-01-17 公開日 2011-03-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1493 Å) 主引用文献 Biochemical and structural characterization of lysophosphatidic Acid binding by a humanized monoclonal antibody. J.Mol.Biol., 408, 2011
3QCU	Crystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (14:0) 分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, LT3015 antibody Fab fragment, heavy chain, ... 著者 Fleming, J.K, Wojciak, J.M, Campbell, M.-A, Huxford, T. 登録日 2011-01-17 公開日 2011-03-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.979 Å) 主引用文献 Biochemical and structural characterization of lysophosphatidic Acid binding by a humanized monoclonal antibody. J.Mol.Biol., 408, 2011
3QCV	Crystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (18:2) 分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9Z,12Z)-octadeca-9,12-dienoate, LT3015 antibody Fab fragment, heavy chain, ... 著者 Fleming, J.K, Wojciak, J.M, Campbell, M.-A, Huxford, T. 登録日 2011-01-17 公開日 2011-03-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Biochemical and structural characterization of lysophosphatidic Acid binding by a humanized monoclonal antibody. J.Mol.Biol., 408, 2011
4GAY	Structure of the broadly neutralizing antibody AP33 分子名称: NEUTRALIZING ANTIBODY AP33 HEAVY CHAIN, NEUTRALIZING ANTIBODY AP33 LIGHT CHAIN, TRIETHYLENE GLYCOL 著者 Potter, J.A, Owsianka, A, Jeffery, N, Matthews, D, Keck, Z, Lau, P, Foung, S.K.H, Taylor, G.L, Patel, A.H. 登録日 2012-07-26 公開日 2012-10-10 最終更新日 2012-11-21 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody. J.Virol., 86, 2012
4R4H	Crystal structure of non-neutralizing, A32-like antibody 2.2c in complex with HIV-1 Env gp120 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c, Heavy chain, ... 著者 Mclellan, J, Acharya, P, Huang, C.-C, Kwong, P.D. 登録日 2014-08-19 公開日 2014-09-17 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (4.28 Å) 主引用文献 Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J.Virol., 88, 2014
1F3R	COMPLEX BETWEEN FV ANTIBODY FRAGMENT AND AN ANALOGUE OF THE MAIN IMMUNOGENIC REGION OF THE ACETYLCHOLINE RECEPTOR 分子名称: ACETYLCHOLINE RECEPTOR ALPHA, FV ANTIBODY FRAGMENT 著者 Kleinjung, J, Petit, M.-C, Orlewski, P, Mamalaki, A, Tzartos, S.-J, Tsikaris, V, Sakarellos-Daitsiotis, M, Sakarellos, C, Marraud, M, Cung, M.-T. 登録日 2000-06-06 公開日 2000-06-15 最終更新日 2021-11-03 実験手法 SOLUTION NMR 主引用文献 The third-dimensional structure of the complex between an Fv antibody fragment and an analogue of the main immunogenic region of the acetylcholine receptor: a combined two-dimensional NMR, homology, and molecular modeling approach. Biopolymers, 53, 2000
8AS0	PD-1 extracellular domain in complex with Fab fragment from D12 antibody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Ongaro, T, Scietti, L, Pluss, L, Peissert, F, Villa, A, Puca, E, De Luca, R, Neri, D, Forneris, F. 登録日 2022-08-17 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Selection of a PD-1 blocking antibody from a novel fully human phage display library. Protein Sci., 31, 2022
4GAJ	Structure of the broadly neutralizing antibody AP33 in complex with its HCV epitope (E2 residues 411-424) 分子名称: Genome polyprotein, NEUTRALIZING ANTIBODY AP33 HEAVY CHAIN, NEUTRALIZING ANTIBODY AP33 LIGHT CHAIN 著者 Potter, J.A, Owsianka, A, Taylor, G.L, Patel, A.H. 登録日 2012-07-25 公開日 2012-10-10 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody. J.Virol., 86, 2012
4U3X	Structure of a human VH antibody domain binding to the cleft of hen egg lysozyme 分子名称: 1,2-ETHANEDIOL, Human VH domain antibody, Lysozyme C 著者 Rouet, R, Langley, D.B, Christ, D. 登録日 2014-07-23 公開日 2015-03-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Fully Human VH Single Domains That Rival the Stability and Cleft Recognition of Camelid Antibodies J.Biol.Chem., 290, 2015

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