3QCT

Crystal structure of the humanized apo LT3015 anti-lysophosphatidic acid antibody Fab fragment

Summary for 3QCT

• Entry DOI: 10.2210/pdb3qct/pdb
• Related: 3QCU 3QCV
• Descriptor: LT3015 antibody Fab fragment, heavy chain, LT3015 antibody Fab fragment, light chain, SULFATE ION, ... (5 entities in total)
• Functional Keywords: antibody, lysophosphatidic acid binding, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted : P01834
• Total number of polymer chains: 2
• Total formula weight: 48220.76

Authors

Fleming, J.K.,Wojciak, J.M.,Campbell, M.-A.,Huxford, T. (deposition date: 2011-01-17, release date: 2011-03-30, Last modification date: 2023-09-13)

• Primary citation: Fleming, J.K.,Wojciak, J.M.,Campbell, M.A.,Huxford, T.; Biochemical and structural characterization of lysophosphatidic Acid binding by a humanized monoclonal antibody.; J.Mol.Biol., 408:462-476, 2011; PubMed: 21392506; DOI: 10.1016/j.jmb.2011.02.061

Experimental method

X-RAY DIFFRACTION (2.1493 Å)