4XAK
Crystal structure of potent neutralizing antibody m336 in complex with MERS Co-V RBD
Summary for 4XAK
Entry DOI | 10.2210/pdb4xak/pdb |
Descriptor | Spike glycoprotein, Heavy chain of neutralizing antibody m336, Light chain of neutralizing antibody m336, ... (6 entities in total) |
Functional Keywords | mers-cov rbd, antibody m336, neutralization, immune system |
Biological source | Human coronavirus EMC (HCoV-EMC) More |
Cellular location | Spike protein S2: Virion membrane ; Single-pass type I membrane protein . Spike protein S1: Virion membrane ; Peripheral membrane protein : K9N5Q8 |
Total number of polymer chains | 6 |
Total formula weight | 155793.68 |
Authors | Zhou, T.,Dimtrov, D.S.,Ying, T. (deposition date: 2014-12-15, release date: 2015-08-26, Last modification date: 2023-09-27) |
Primary citation | Ying, T.,Prabakaran, P.,Du, L.,Shi, W.,Feng, Y.,Wang, Y.,Wang, L.,Li, W.,Jiang, S.,Dimitrov, D.S.,Zhou, T. Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody. Nat Commun, 6:8223-8223, 2015 Cited by PubMed: 26370782DOI: 10.1038/ncomms9223 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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